| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the cyclizine-1731 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| AMT | aminomethyltransferase |
| ANGEL1 | angel homolog 1 (Drosophila) |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ATG10 | autophagy related 10 |
| ATXN2 | ataxin 2 |
| B3GNT1 | |
| BCL6 | B-cell CLL/lymphoma 6 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CD177 | CD177 molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDK16 | cyclin-dependent kinase 16 |
| CELA3A | chymotrypsin-like elastase family, member 3A |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| CTSE | cathepsin E |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DPYSL3 | dihydropyrimidinase-like 3 |
| ELK1 | ELK1, member of ETS oncogene family |
| EPHB1 | EPH receptor B1 |
| ERCC6L | excision repair cross-complementation group 6-like |
| FAM3A | family with sequence similarity 3, member A |
| FASTK | Fas-activated serine/threonine kinase |
| GDNF | glial cell derived neurotrophic factor |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GOLGA1 | golgin A1 |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GPR21 | G protein-coupled receptor 21 |
| GUCA1B | guanylate cyclase activator 1B (retina) |
| HNF1A | HNF1 homeobox A |
| HOMER1 | homer scaffolding protein 1 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| ITGA7 | integrin, alpha 7 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KIAA0894 | KIAA0894 protein |
| KLHL28 | kelch-like family member 28 |
| KLHL35 | kelch-like family member 35 |
| LMAN1 | lectin, mannose-binding, 1 |
| MAGED2 | melanoma antigen family D2 |
| MAML3 | mastermind-like 3 (Drosophila) |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MOB3B | MOB kinase activator 3B |
| MXRA8 | matrix-remodelling associated 8 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle |
| NADK | NAD kinase |
| NCDN | neurochondrin |
| NDRG2 | NDRG family member 2 |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NFYA | nuclear transcription factor Y, alpha |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NXPH3 | neurexophilin 3 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OLFM1 | olfactomedin 1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PARD3 | par-3 family cell polarity regulator |
| PAX3 | paired box 3 |
| PCGF2 | polycomb group ring finger 2 |
| PDCD11 | programmed cell death 11 |
| PIAS4 | protein inhibitor of activated STAT, 4 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLIN2 | perilipin 2 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRRC2B | proline-rich coiled-coil 2B |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| RHOT2 | ras homolog family member T2 |
| RWDD2A | RWD domain containing 2A |
| S100A14 | S100 calcium binding protein A14 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCAF4 | SR-related CTD-associated factor 4 |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SIRT3 | sirtuin 3 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SPHK1 | sphingosine kinase 1 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPPL2B | signal peptide peptidase like 2B |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TDRD3 | tudor domain containing 3 |
| TMEM161A | transmembrane protein 161A |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TRAF1 | TNF receptor-associated factor 1 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| WDR19 | WD repeat domain 19 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WWC1 | WW and C2 domain containing 1 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| ZNF280D | zinc finger protein 280D |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTN4 | actinin, alpha 4 |
| ANPEP | alanyl (membrane) aminopeptidase |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| CARD9 | caspase recruitment domain family, member 9 |
| CARM1 | coactivator-associated arginine methyltransferase 1 |
| CCBL2 | cysteine conjugate-beta lyase 2 |
| CCNT1 | cyclin T1 |
| CDC73 | cell division cycle 73 |
| CER1 | cerberus 1, DAN family BMP antagonist |
| CFAP74 | cilia and flagella associated protein 74 |
| CHMP1A | charged multivesicular body protein 1A |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CRY1 | cryptochrome circadian clock 1 |
| CS | citrate synthase |
| CSRNP2 | cysteine-serine-rich nuclear protein 2 |
| DBF4 | DBF4 zinc finger |
| DCLRE1B | DNA cross-link repair 1B |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 |
| DHDDS | dehydrodolichyl diphosphate synthase |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
| DOK2 | docking protein 2, 56kDa |
| DOLPP1 | dolichyldiphosphatase 1 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| DYSF | dysferlin |
| ELMO1 | engulfment and cell motility 1 |
| ERF | Ets2 repressor factor |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| FADS2 | fatty acid desaturase 2 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FAM188A | family with sequence similarity 188, member A |
| FAT1 | FAT atypical cadherin 1 |
| FKTN | fukutin |
| FOXJ2 | forkhead box J2 |
| FOXK2 | forkhead box K2 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| KIAA0753 | KIAA0753 |
| KIAA1598 | |
| KIF20B | kinesin family member 20B |
| KIZ | kizuna centrosomal protein |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MATK | megakaryocyte-associated tyrosine kinase |
| MFF | mitochondrial fission factor |
| MORC3 | MORC family CW-type zinc finger 3 |
| MPHOSPH8 | M-phase phosphoprotein 8 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRGBP | MRG/MORF4L binding protein |
| MRPL28 | mitochondrial ribosomal protein L28 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NHLRC2 | NHL repeat containing 2 |
| NOTCH1 | notch 1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NUBP2 | nucleotide binding protein 2 |
| ORC1 | origin recognition complex, subunit 1 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 |
| PLA2G12A | phospholipase A2, group XIIA |
| POGLUT1 | protein O-glucosyltransferase 1 |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
| PTER | phosphotriesterase related |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| RAB4B | RAB4B, member RAS oncogene family |
| RAD54L | RAD54-like (S. cerevisiae) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SEPW1 | selenoprotein W, 1 |
| SIRT1 | sirtuin 1 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SPON2 | spondin 2, extracellular matrix protein |
| SRBD1 | S1 RNA binding domain 1 |
| STAG3 | stromal antigen 3 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| SUOX | sulfite oxidase |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRIM26 | tripartite motif containing 26 |
| UBA5 | ubiquitin-like modifier activating enzyme 5 |
| UBXN8 | UBX domain protein 8 |
| URGCP | upregulator of cell proliferation |
| XYLT1 | xylosyltransferase I |
| YEATS4 | YEATS domain containing 4 |
