| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the cyclizine-2880 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| ADRA1A | adrenoceptor alpha 1A |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARL4C | ADP-ribosylation factor-like 4C |
| ARTN | artemin |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATN1 | atrophin 1 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CD48 | CD48 molecule |
| CD58 | CD58 molecule |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNTN1 | contactin 1 |
| COPA | coatomer protein complex, subunit alpha |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CRLF2 | cytokine receptor-like factor 2 |
| CTNS | cystinosin, lysosomal cystine transporter |
| DNM3 | dynamin 3 |
| DNMBP | dynamin binding protein |
| DTNB | dystrobrevin, beta |
| ELN | elastin |
| ERCC2 | excision repair cross-complementation group 2 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GPR157 | G protein-coupled receptor 157 |
| GYG2 | glycogenin 2 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIC2 | hypermethylated in cancer 2 |
| HR | hair growth associated |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IDUA | iduronidase, alpha-L- |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| ING2 | inhibitor of growth family, member 2 |
| IRF4 | interferon regulatory factor 4 |
| JAK3 | Janus kinase 3 |
| KLHL25 | kelch-like family member 25 |
| LOXL3 | lysyl oxidase-like 3 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LUZP4 | leucine zipper protein 4 |
| MLXIP | MLX interacting protein |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MST1L | macrophage stimulating 1-like |
| NEUROD1 | neuronal differentiation 1 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NRTN | neurturin |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDHB11 | protocadherin beta 11 |
| PICK1 | protein interacting with PRKCA 1 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| POU4F1 | POU class 4 homeobox 1 |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| PRLR | prolactin receptor |
| RASA3 | RAS p21 protein activator 3 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RUSC2 | RUN and SH3 domain containing 2 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCNN1G | sodium channel, non voltage gated 1 gamma subunit |
| SDC2 | syndecan 2 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLN | sarcolipin |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SPTB | spectrin, beta, erythrocytic |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STIM1 | stromal interaction molecule 1 |
| SYNC | syncoilin, intermediate filament protein |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TGFB2 | transforming growth factor, beta 2 |
| TMOD2 | tropomodulin 2 (neuronal) |
| TMX4 | thioredoxin-related transmembrane protein 4 |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 |
| TOP3B | topoisomerase (DNA) III beta |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TTYH1 | tweety family member 1 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VCAN | versican |
| WAS | Wiskott-Aldrich syndrome |
| WDR55 | WD repeat domain 55 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF230 | zinc finger protein 230 |
| ZNF639 | zinc finger protein 639 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| AMT | aminomethyltransferase |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BBS10 | Bardet-Biedl syndrome 10 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C3 | complement component 3 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CDK3 | cyclin-dependent kinase 3 |
| CENPO | centromere protein O |
| CFD | complement factor D (adipsin) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DIXDC1 | DIX domain containing 1 |
| DMTN | dematin actin binding protein |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| EPPK1 | epiplakin 1 |
| F2R | coagulation factor II (thrombin) receptor |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FFAR2 | free fatty acid receptor 2 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRB7 | growth factor receptor-bound protein 7 |
| HIST1H4E | histone cluster 1, H4e |
| HOXC5 | homeobox C5 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| IQCG | IQ motif containing G |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0754 | KIAA0754 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| METTL2B | methyltransferase like 2B |
| MFAP2 | microfibrillar-associated protein 2 |
| MGC12488 | |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MT1H | metallothionein 1H |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NLRX1 | NLR family member X1 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NRSN2 | neurensin 2 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OSMR | oncostatin M receptor |
| PARG | poly (ADP-ribose) glycohydrolase |
| PER3 | period circadian clock 3 |
| PGP | phosphoglycolate phosphatase |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PHF14 | PHD finger protein 14 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLCD1 | phospholipase C, delta 1 |
| PLXNA3 | plexin A3 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PROS1 | protein S (alpha) |
| PRR14L | proline rich 14-like |
| RAB30 | RAB30, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RBL1 | retinoblastoma-like 1 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RNF2 | ring finger protein 2 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCAI | suppressor of cancer cell invasion |
| SIRT6 | sirtuin 6 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| TAOK1 | TAO kinase 1 |
| TGS1 | trimethylguanosine synthase 1 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM180 | transmembrane protein 180 |
| TMEM183A | transmembrane protein 183A |
| TSPAN15 | tetraspanin 15 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| WLS | wntless Wnt ligand secretion mediator |
| YY2 | YY2 transcription factor |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF134 | zinc finger protein 134 |
