| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
196 genes differentially expressed following the cyclizine-5100 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AIM1L | absent in melanoma 1-like |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| APBA3 | amyloid beta (A4) precursor protein-binding, family A, member 3 |
| ATF7IP | activating transcription factor 7 interacting protein |
| BMP8B | bone morphogenetic protein 8b |
| BTBD7 | BTB (POZ) domain containing 7 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1S | complement component 1, s subcomponent |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CA9 | carbonic anhydrase IX |
| CCNO | cyclin O |
| CDK13 | cyclin-dependent kinase 13 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DCAF11 | DDB1 and CUL4 associated factor 11 |
| DCHS2 | dachsous cadherin-related 2 |
| DDN | dendrin |
| DENND2A | DENN/MADD domain containing 2A |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| EDC3 | enhancer of mRNA decapping 3 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM46C | family with sequence similarity 46, member C |
| FGF1 | fibroblast growth factor 1 (acidic) |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GPR182 | G protein-coupled receptor 182 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| HCFC1 | host cell factor C1 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXB5 | homeobox B5 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| KLHL22 | kelch-like family member 22 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LAT2 | linker for activation of T cells family, member 2 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOXL2 | lysyl oxidase-like 2 |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LRRC15 | leucine rich repeat containing 15 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MYO1D | myosin ID |
| MYO1F | myosin IF |
| MYOF | myoferlin |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NUP50 | nucleoporin 50kDa |
| OSBPL10 | oxysterol binding protein-like 10 |
| PCYT1B | phosphate cytidylyltransferase 1, choline, beta |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PROSER1 | proline and serine rich 1 |
| PTPRF | protein tyrosine phosphatase, receptor type, F |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RABGAP1 | RAB GTPase activating protein 1 |
| RARG | retinoic acid receptor, gamma |
| RBBP9 | retinoblastoma binding protein 9 |
| REG1A | regenerating islet-derived 1 alpha |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SATB2 | SATB homeobox 2 |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| STRN | striatin, calmodulin binding protein |
| SUN1 | Sad1 and UNC84 domain containing 1 |
| TAOK1 | TAO kinase 1 |
| TFDP3 | transcription factor Dp family, member 3 |
| TLN2 | talin 2 |
| TMEM231 | transmembrane protein 231 |
| TMEM63A | transmembrane protein 63A |
| TOM1 | target of myb1 (chicken) |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TTC30A | tetratricopeptide repeat domain 30A |
| TTC39A | tetratricopeptide repeat domain 39A |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VPS9D1 | VPS9 domain containing 1 |
| WAS | Wiskott-Aldrich syndrome |
| WSB1 | WD repeat and SOCS box containing 1 |
| XYLB | xylulokinase homolog (H. influenzae) |
| XYLT2 | xylosyltransferase II |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZBTB14 | zinc finger and BTB domain containing 14 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF268 | zinc finger protein 268 |
| ZNF695 | zinc finger protein 695 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABHD8 | abhydrolase domain containing 8 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ALS2CL | ALS2 C-terminal like |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BEND5 | BEN domain containing 5 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CCDC85C | coiled-coil domain containing 85C |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CFAP45 | cilia and flagella associated protein 45 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CSF1R | colony stimulating factor 1 receptor |
| DCLRE1B | DNA cross-link repair 1B |
| DNAL4 | dynein, axonemal, light chain 4 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EGF | epidermal growth factor |
| FAM186A | family with sequence similarity 186, member A |
| FANCC | Fanconi anemia, complementation group C |
| FMO4 | flavin containing monooxygenase 4 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HINFP | histone H4 transcription factor |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H3C | histone cluster 1, H3c |
| HOXA4 | homeobox A4 |
| HOXC10 | homeobox C10 |
| IFNA2 | interferon, alpha 2 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL22 | interleukin 22 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCC | mutated in colorectal cancers |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MXRA8 | matrix-remodelling associated 8 |
| MYH15 | myosin, heavy chain 15 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NIPAL2 | NIPA-like domain containing 2 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NTF3 | neurotrophin 3 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| OSBP2 | oxysterol binding protein 2 |
| OSR2 | odd-skipped related transciption factor 2 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PHF14 | PHD finger protein 14 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| QSER1 | glutamine and serine rich 1 |
| RAB3A | RAB3A, member RAS oncogene family |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS17 | regulator of G-protein signaling 17 |
| RNF2 | ring finger protein 2 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SDC3 | syndecan 3 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC35F6 | solute carrier family 35, member F6 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STEAP4 | STEAP family member 4 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TMEM132A | transmembrane protein 132A |
| TMEM51 | transmembrane protein 51 |
| USP19 | ubiquitin specific peptidase 19 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VWA1 | von Willebrand factor A domain containing 1 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF177 | zinc finger protein 177 |
| ZNF225 | zinc finger protein 225 |
| ZNF93 | zinc finger protein 93 |