| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the cyclobenzaprine-1332 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| AEN | apoptosis enhancing nuclease |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ANXA3 | annexin A3 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CAPN15 | calpain 15 |
| CCNT1 | cyclin T1 |
| CEP290 | centrosomal protein 290kDa |
| CHMP6 | charged multivesicular body protein 6 |
| COL4A2 | collagen, type IV, alpha 2 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CPQ | carboxypeptidase Q |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| DBN1 | drebrin 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DMXL2 | Dmx-like 2 |
| DUSP1 | dual specificity phosphatase 1 |
| EMILIN2 | elastin microfibril interfacer 2 |
| EML3 | echinoderm microtubule associated protein like 3 |
| EVA1B | eva-1 homolog B (C. elegans) |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAS | Fas cell surface death receptor |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) |
| FCMR | Fc fragment of IgM receptor |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| HEMK1 | HemK methyltransferase family member 1 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOMER3 | homer scaffolding protein 3 |
| HSPA4 | heat shock 70kDa protein 4 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL24 | interleukin 24 |
| INCENP | inner centromere protein antigens 135/155kDa |
| JAG2 | jagged 2 |
| JMJD4 | jumonji domain containing 4 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LARP4B | La ribonucleoprotein domain family, member 4B |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| METTL1 | methyltransferase like 1 |
| MPZL1 | myelin protein zero-like 1 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PDZD7 | PDZ domain containing 7 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLSCR3 | phospholipid scramblase 3 |
| PMM2 | phosphomannomutase 2 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F |
| PPP2R4 | protein phosphatase 2A activator, regulatory subunit 4 |
| PTAFR | platelet-activating factor receptor |
| RIN3 | Ras and Rab interactor 3 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPATA2L | spermatogenesis associated 2-like |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| ST7 | suppression of tumorigenicity 7 |
| STAT5A | signal transducer and activator of transcription 5A |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TDRD3 | tudor domain containing 3 |
| TERT | telomerase reverse transcriptase |
| TFEB | transcription factor EB |
| TK2 | thymidine kinase 2, mitochondrial |
| TPCN1 | two pore segment channel 1 |
| TPD52L1 | tumor protein D52-like 1 |
| TRAIP | TRAF interacting protein |
| TRMT61A | tRNA methyltransferase 61A |
| UBOX5 | U-box domain containing 5 |
| USP36 | ubiquitin specific peptidase 36 |
| VCAN | versican |
| VILL | villin-like |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZNF202 | zinc finger protein 202 |
| ZNF224 | zinc finger protein 224 |
| ZNF254 | zinc finger protein 254 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABT1 | activator of basal transcription 1 |
| ADORA3 | adenosine A3 receptor |
| AES | amino-terminal enhancer of split |
| AGO4 | argonaute RISC catalytic component 4 |
| ANO10 | anoctamin 10 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APH1B | APH1B gamma secretase subunit |
| ARMC7 | armadillo repeat containing 7 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATAD2 | ATPase family, AAA domain containing 2 |
| BPI | bactericidal/permeability-increasing protein |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CHMP1A | charged multivesicular body protein 1A |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLSPN | claspin |
| CSAD | cysteine sulfinic acid decarboxylase |
| DBF4B | DBF4 zinc finger B |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EDC3 | enhancer of mRNA decapping 3 |
| EMD | emerin |
| EML4 | echinoderm microtubule associated protein like 4 |
| FAM57A | family with sequence similarity 57, member A |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FKBP9 | FK506 binding protein 9, 63 kDa |
| FLCN | folliculin |
| GCH1 | GTP cyclohydrolase 1 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPS1 | G protein pathway suppressor 1 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H2AG | histone cluster 1, H2ag |
| HIST1H2BI | histone cluster 1, H2bi |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFT81 | intraflagellar transport 81 |
| KIAA0355 | KIAA0355 |
| KLHL26 | kelch-like family member 26 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MBD5 | methyl-CpG binding domain protein 5 |
| MED9 | mediator complex subunit 9 |
| METTL22 | methyltransferase like 22 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| NABP2 | nucleic acid binding protein 2 |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| NUBP1 | nucleotide binding protein 1 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PGPEP1 | pyroglutamyl-peptidase I |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLA2G15 | phospholipase A2, group XV |
| PLS1 | plastin 1 |
| PTGES2 | prostaglandin E synthase 2 |
| RAB23 | RAB23, member RAS oncogene family |
| RAB4B | RAB4B, member RAS oncogene family |
| RNF122 | ring finger protein 122 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SALL2 | spalt-like transcription factor 2 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SIDT1 | SID1 transmembrane family, member 1 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SMA4 | glucuronidase, beta pseudogene |
| STX5 | syntaxin 5 |
| SYNJ2BP | synaptojanin 2 binding protein |
| TAOK1 | TAO kinase 1 |
| TBX19 | T-box 19 |
| TCTN2 | tectonic family member 2 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TXLNG | taxilin gamma |
| USB1 | U6 snRNA biogenesis 1 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF14 | zinc finger protein 14 |
| ZNF665 | zinc finger protein 665 |
| ZNF747 | zinc finger protein 747 |
