| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the cyclobenzaprine-3268 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC8 | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 |
| ACVR1B | activin A receptor, type IB |
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| AFAP1 | actin filament associated protein 1 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| APOL2 | apolipoprotein L, 2 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BAIAP3 | BAI1-associated protein 3 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BBS9 | Bardet-Biedl syndrome 9 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIN1 | bridging integrator 1 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCNT2 | cyclin T2 |
| CD8A | CD8a molecule |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| CNTN1 | contactin 1 |
| CPNE7 | copine VII |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DFNB31 | deafness, autosomal recessive 31 |
| DMPK | dystrophia myotonica-protein kinase |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGF5 | fibroblast growth factor 5 |
| GLRX | glutaredoxin (thioltransferase) |
| GM2A | GM2 ganglioside activator |
| GPATCH3 | G patch domain containing 3 |
| GPR137 | G protein-coupled receptor 137 |
| HAP1 | huntingtin-associated protein 1 |
| HR | hair growth associated |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFT54 | intraflagellar transport 54 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IL11 | interleukin 11 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KAT6A | K(lysine) acetyltransferase 6A |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA1456 | KIAA1456 |
| LEPROT | leptin receptor overlapping transcript |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MARS | methionyl-tRNA synthetase |
| MED15 | mediator complex subunit 15 |
| MFAP3 | microfibrillar-associated protein 3 |
| MTM1 | myotubularin 1 |
| MUC3B | mucin 3B, cell surface associated |
| MYOZ3 | myozenin 3 |
| NPC1 | Niemann-Pick disease, type C1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDCD6 | programmed cell death 6 |
| PER1 | period circadian clock 1 |
| PLA2G3 | phospholipase A2, group III |
| PLIN2 | perilipin 2 |
| PMEL | premelanosome protein |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PTCRA | pre T-cell antigen receptor alpha |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RAB11B | RAB11B, member RAS oncogene family |
| RAD54B | RAD54 homolog B (S. cerevisiae) |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 |
| RGS10 | regulator of G-protein signaling 10 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SPHK2 | sphingosine kinase 2 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SQLE | squalene epoxidase |
| STC1 | stanniocalcin 1 |
| STK3 | serine/threonine kinase 3 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYMPK | symplekin |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TBX19 | T-box 19 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TP63 | tumor protein p63 |
| TP73-AS1 | TP73 antisense RNA 1 |
| UBA7 | ubiquitin-like modifier activating enzyme 7 |
| VLDLR | very low density lipoprotein receptor |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF10 | zinc finger protein 10 |
| ZNF235 | zinc finger protein 235 |
| ZNF862 | zinc finger protein 862 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARMC4 | armadillo repeat containing 4 |
| ATG2B | autophagy related 2B |
| ATG9A | autophagy related 9A |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BEX4 | brain expressed, X-linked 4 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CCDC170 | coiled-coil domain containing 170 |
| CERS4 | ceramide synthase 4 |
| CHMP6 | charged multivesicular body protein 6 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EMID1 | EMI domain containing 1 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC4 | excision repair cross-complementation group 4 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FUZ | fuzzy planar cell polarity protein |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPR19 | G protein-coupled receptor 19 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC7 | histone deacetylase 7 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H4F | histone cluster 1, H4f |
| HOXC10 | homeobox C10 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KIAA0754 | KIAA0754 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LPXN | leupaxin |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MCC | mutated in colorectal cancers |
| MED18 | mediator complex subunit 18 |
| MGC12488 | |
| NAV2 | neuron navigator 2 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| ONECUT2 | one cut homeobox 2 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| OVOL1 | ovo-like zinc finger 1 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| POLH | polymerase (DNA directed), eta |
| PRAMEF11 | PRAME family member 11 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RIN1 | Ras and Rab interactor 1 |
| RNF2 | ring finger protein 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SIX1 | SIX homeobox 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC35E3 | solute carrier family 35, member E3 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SNHG20 | small nucleolar RNA host gene 20 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| TAOK1 | TAO kinase 1 |
| TEX40 | testis expressed 40 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM209 | transmembrane protein 209 |
| TTC33 | tetratricopeptide repeat domain 33 |
| UNC119 | unc-119 homolog (C. elegans) |
| USP36 | ubiquitin specific peptidase 36 |
| VASH1 | vasohibin 1 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| WDR76 | WD repeat domain 76 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF324 | zinc finger protein 324 |
| ZNF552 | zinc finger protein 552 |
| ZNF571 | zinc finger protein 571 |
| ZNF652 | zinc finger protein 652 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
