| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the cyclobenzaprine-4252 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ANTXR1 | anthrax toxin receptor 1 |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ART1 | ADP-ribosyltransferase 1 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CACNG5 | calcium channel, voltage-dependent, gamma subunit 5 |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC170 | coiled-coil domain containing 170 |
| CD226 | CD226 molecule |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLIC2 | chloride intracellular channel 2 |
| CLMN | calmin (calponin-like, transmembrane) |
| CLTC | clathrin, heavy chain (Hc) |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| CNTFR | ciliary neurotrophic factor receptor |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CST1 | cystatin SN |
| CST4 | cystatin S |
| CTSS | cathepsin S |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| EDA | ectodysplasin A |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 |
| EPS8L1 | EPS8-like 1 |
| ESRRG | estrogen-related receptor gamma |
| ETV6 | ets variant 6 |
| FAM65B | family with sequence similarity 65, member B |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGFR1 | fibroblast growth factor receptor 1 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GRK4 | G protein-coupled receptor kinase 4 |
| HCG4B | HLA complex group 4B (non-protein coding) |
| HEG1 | heart development protein with EGF-like domains 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HES2 | hes family bHLH transcription factor 2 |
| HTR5A | 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled |
| IL6 | interleukin 6 |
| INO80D | INO80 complex subunit D |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIF1C | kinesin family member 1C |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 |
| KRT34 | keratin 34, type I |
| LAT2 | linker for activation of T cells family, member 2 |
| LIMD2 | LIM domain containing 2 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LRRC75B | leucine rich repeat containing 75B |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MST1 | macrophage stimulating 1 |
| MUC3B | mucin 3B, cell surface associated |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NCALD | neurocalcin delta |
| NEU3 | sialidase 3 (membrane sialidase) |
| NPFF | neuropeptide FF-amide peptide precursor |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUP54 | nucleoporin 54kDa |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PAX5 | paired box 5 |
| PCDH17 | protocadherin 17 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PKP4 | plakophilin 4 |
| PLCG1 | phospholipase C, gamma 1 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PP14571 | uncharacterized LOC100130449 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTAFR | platelet-activating factor receptor |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| RAB2A | RAB2A, member RAS oncogene family |
| RAB6A | RAB6A, member RAS oncogene family |
| RFPL3 | ret finger protein-like 3 |
| RPL10L | ribosomal protein L10-like |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SFRP5 | secreted frizzled-related protein 5 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SP4 | Sp4 transcription factor |
| SRCAP | Snf2-related CREBBP activator protein |
| SV2B | synaptic vesicle glycoprotein 2B |
| SYT17 | synaptotagmin XVII |
| VASH1 | vasohibin 1 |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AFAP1 | actin filament associated protein 1 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALOX12 | arachidonate 12-lipoxygenase |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| AXIN1 | axin 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BTC | betacellulin |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD101 | CD101 molecule |
| CLCA1 | chloride channel accessory 1 |
| CNN1 | calponin 1, basic, smooth muscle |
| COL9A2 | collagen, type IX, alpha 2 |
| COMP | cartilage oligomeric matrix protein |
| CXORF21 | chromosome X open reading frame 21 |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| DOK5 | docking protein 5 |
| EGOT | eosinophil granule ontogeny transcript (non-protein coding) |
| ERCC4 | excision repair cross-complementation group 4 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GPATCH2L | G patch domain containing 2-like |
| GPR19 | G protein-coupled receptor 19 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H2AK | histone cluster 1, H2ak |
| HPR | haptoglobin-related protein |
| IFI44L | interferon-induced protein 44-like |
| IFNA14 | interferon, alpha 14 |
| IFT140 | intraflagellar transport 140 |
| IL36RN | interleukin 36 receptor antagonist |
| IQCG | IQ motif containing G |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LENEP | lens epithelial protein |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOXL3 | lysyl oxidase-like 3 |
| LRRC37A4P | leucine rich repeat containing 37, member A4, pseudogene |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAGEA6 | melanoma antigen family A6 |
| MED31 | mediator complex subunit 31 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTA2 | metastasis associated 1 family, member 2 |
| MYO15A | myosin XVA |
| NOTCH4 | notch 4 |
| OLFML2B | olfactomedin-like 2B |
| OR10H1 | olfactory receptor, family 10, subfamily H, member 1 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PDE8B | phosphodiesterase 8B |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PODNL1 | podocan-like 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRM2 | protamine 2 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RAB40A | RAB40A, member RAS oncogene family |
| RBM12B-AS1 | RBM12B antisense RNA 1 |
| RFPL1 | ret finger protein-like 1 |
| RIN1 | Ras and Rab interactor 1 |
| RNF2 | ring finger protein 2 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| STEAP4 | STEAP family member 4 |
| TEX40 | testis expressed 40 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TWISTNB | TWIST neighbor |
| USB1 | U6 snRNA biogenesis 1 |
| USP20 | ubiquitin specific peptidase 20 |
| VLDLR | very low density lipoprotein receptor |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZFHX3 | zinc finger homeobox 3 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF140 | zinc finger protein 140 |
| ZNF639 | zinc finger protein 639 |
| ZNF768 | zinc finger protein 768 |
