| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the cyclobenzaprine-4834 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ACRV1 | acrosomal vesicle protein 1 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACVR1B | activin A receptor, type IB |
| AFF2 | AF4/FMR2 family, member 2 |
| AGFG1 | ArfGAP with FG repeats 1 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ATF7IP | activating transcription factor 7 interacting protein |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BCL2L2 | BCL2-like 2 |
| BMP2 | bone morphogenetic protein 2 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CELA2A | chymotrypsin-like elastase family, member 2A |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CEP112 | centrosomal protein 112kDa |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DOCK5 | dedicator of cytokinesis 5 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| DUSP4 | dual specificity phosphatase 4 |
| EMP1 | epithelial membrane protein 1 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| ETV5 | ets variant 5 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FOXG1 | forkhead box G1 |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| H2AFX | H2A histone family, member X |
| HAMP | hepcidin antimicrobial peptide |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOXA10 | homeobox A10 |
| HSPA13 | heat shock protein 70kDa family, member 13 |
| IDS | iduronate 2-sulfatase |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| INHBE | inhibin, beta E |
| INSIG1 | insulin induced gene 1 |
| IRS2 | insulin receptor substrate 2 |
| ITGA6 | integrin, alpha 6 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| LAMC2 | laminin, gamma 2 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LPIN1 | lipin 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALL | mal, T-cell differentiation protein-like |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MED25 | mediator complex subunit 25 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NMT2 | N-myristoyltransferase 2 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PEX5L | peroxisomal biogenesis factor 5-like |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLAU | plasminogen activator, urokinase |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| POMT2 | protein-O-mannosyltransferase 2 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PTHLH | parathyroid hormone-like hormone |
| PURG | purine-rich element binding protein G |
| RAB6A | RAB6A, member RAS oncogene family |
| RGSL1 | regulator of G-protein signaling like 1 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SGMS1 | sphingomyelin synthase 1 |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SLC5A1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SNAI2 | snail family zinc finger 2 |
| SP1 | Sp1 transcription factor |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) |
| TAGLN3 | transgelin 3 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBL2 | transducin (beta)-like 2 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZNF287 | zinc finger protein 287 |
| ZNF442 | zinc finger protein 442 |
| ZNF646 | zinc finger protein 646 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| BAK1 | BCL2-antagonist/killer 1 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CASZ1 | castor zinc finger 1 |
| CBX4 | chromobox homolog 4 |
| CDK3 | cyclin-dependent kinase 3 |
| CEP85 | centrosomal protein 85kDa |
| CHPF | chondroitin polymerizing factor |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CPNE1 | copine I |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CUL9 | cullin 9 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DDB1 | damage-specific DNA binding protein 1, 127kDa |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DOCK4 | dedicator of cytokinesis 4 |
| DUSP2 | dual specificity phosphatase 2 |
| EDC4 | enhancer of mRNA decapping 4 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ERAL1 | Era-like 12S mitochondrial rRNA chaperone 1 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETNK2 | ethanolamine kinase 2 |
| FADS2 | fatty acid desaturase 2 |
| FAM63A | family with sequence similarity 63, member A |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FBRS | fibrosin |
| FPGS | folylpolyglutamate synthase |
| FUZ | fuzzy planar cell polarity protein |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GMPR | guanosine monophosphate reductase |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GRB7 | growth factor receptor-bound protein 7 |
| GSTA4 | glutathione S-transferase alpha 4 |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMNB2 | lamin B2 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MEIS1 | Meis homeobox 1 |
| MFAP2 | microfibrillar-associated protein 2 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MORC4 | MORC family CW-type zinc finger 4 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MTMR12 | myotubularin related protein 12 |
| MVP | major vault protein |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa |
| NRSN2 | neurensin 2 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PCBP4 | poly(rC) binding protein 4 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PITX2 | paired-like homeodomain 2 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLIN3 | perilipin 3 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RNH1 | ribonuclease/angiogenin inhibitor 1 |
| RNMTL1 | RNA methyltransferase like 1 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SNRNP40 | small nuclear ribonucleoprotein 40kDa (U5) |
| STRA6 | stimulated by retinoic acid 6 |
| STX1A | syntaxin 1A (brain) |
| TCTN1 | tectonic family member 1 |
| TFF2 | trefoil factor 2 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TLN1 | talin 1 |
| TMEM104 | transmembrane protein 104 |
| TMEM183A | transmembrane protein 183A |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| UPK2 | uroplakin 2 |
| URM1 | ubiquitin related modifier 1 |
| VGF | VGF nerve growth factor inducible |
| WLS | wntless Wnt ligand secretion mediator |
| XAB2 | XPA binding protein 2 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF16 | zinc finger protein 16 |
| ZNF324 | zinc finger protein 324 |
| ZNF611 | zinc finger protein 611 |
| ZNF701 | zinc finger protein 701 |
