cyclohydrolase activity Gene Set

Dataset	GO Molecular Function Annotations 2015
Category	structural or functional annotations
Type	molecular function
Description	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2, in a reaction that involves the opening of a ring. (Gene Ontology, GO_0019238)
External Link	http://amigo.geneontology.org/amigo/term/GO:0019238
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Genes

7 genes performing the cyclohydrolase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

Symbol	Name
ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
GCH1	GTP cyclohydrolase 1
MTHFD1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
MTHFD2	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MTHFD2L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NIF3L1	NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)