cyclooxygenase pathway Gene Set
Dataset
GO Biological Process Annotations 2015
Category
structural or functional annotations
Type
biological process
Description
The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2. (Gene Ontology , GO_0019371 )
External Link
http://amigo.geneontology.org/amigo/term/GO:0019371
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Genes
14 genes participating in the cyclooxygenase pathway biological process from the curated GO Biological Process Annotations 2015 dataset.
Symbol
Name
AKR1C3
aldo-keto reductase family 1, member C3
CBR1
carbonyl reductase 1
FAM213B
family with sequence similarity 213, member B
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
HPGDS
hematopoietic prostaglandin D synthase
PTGDS
prostaglandin D2 synthase 21kDa (brain)
PTGES
prostaglandin E synthase
PTGES3
prostaglandin E synthase 3 (cytosolic)
PTGIS
prostaglandin I2 (prostacyclin) synthase
PTGR1
prostaglandin reductase 1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SPHK1
sphingosine kinase 1
TBXAS1
thromboxane A synthase 1 (platelet)