cyclopia Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Cyclopia is a congenital abnormality in which there is only one eye. That eye is centrally placed in the area normally occupied by the root of the nose. (Human Phenotype Ontology, HP_0009914)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005163
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Genes

9 gene mutations causing the cyclopia phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACVR2A activin A receptor, type IIA
COL2A1 collagen, type II, alpha 1
DISP1 dispatched homolog 1 (Drosophila)
FAT1 FAT atypical cadherin 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PGAP1 post-GPI attachment to proteins 1
SHH sonic hedgehog
TDGF1 teratocarcinoma-derived growth factor 1
TWSG1 twisted gastrulation BMP signaling modulator 1