| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the cycloserine-3562 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| B9D2 | B9 protein domain 2 |
| BDKRB2 | bradykinin receptor B2 |
| BGN | biglycan |
| C1QB | complement component 1, q subcomponent, B chain |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CACTIN | cactin, spliceosome C complex subunit |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CDA | cytidine deaminase |
| CDK19 | cyclin-dependent kinase 19 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CLEC3B | C-type lectin domain family 3, member B |
| COL1A2 | collagen, type I, alpha 2 |
| COL8A1 | collagen, type VIII, alpha 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CTSF | cathepsin F |
| DAPK2 | death-associated protein kinase 2 |
| DFNB31 | deafness, autosomal recessive 31 |
| DOCK4 | dedicator of cytokinesis 4 |
| EFNB3 | ephrin-B3 |
| EN2 | engrailed homeobox 2 |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GPR153 | G protein-coupled receptor 153 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HMG20B | high mobility group 20B |
| HOMER3 | homer scaffolding protein 3 |
| HPX | hemopexin |
| HSD3B1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
| ICAM5 | intercellular adhesion molecule 5, telencephalin |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| INHBA | inhibin, beta A |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| JMJD4 | jumonji domain containing 4 |
| KHSRP | KH-type splicing regulatory protein |
| KIAA0195 | KIAA0195 |
| KIAA1462 | KIAA1462 |
| KLF12 | Kruppel-like factor 12 |
| KRT6B | keratin 6B, type II |
| LAMC3 | laminin, gamma 3 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LOC100131532 | uncharacterized LOC100131532 |
| MCF2 | MCF.2 cell line derived transforming sequence |
| MED9 | mediator complex subunit 9 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow |
| NGFR | nerve growth factor receptor |
| NME5 | NME/NM23 family member 5 |
| NOX1 | NADPH oxidase 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLCG1 | phospholipase C, gamma 1 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTPRB | protein tyrosine phosphatase, receptor type, B |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RGS1 | regulator of G-protein signaling 1 |
| RND1 | Rho family GTPase 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SORCS3 | sortilin-related VPS10 domain containing receptor 3 |
| STRA6 | stimulated by retinoic acid 6 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| SYK | spleen tyrosine kinase |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TH | tyrosine hydroxylase |
| TNC | tenascin C |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TPP1 | tripeptidyl peptidase I |
| TRIM38 | tripartite motif containing 38 |
| TRIM49 | tripartite motif containing 49 |
| TUBBP5 | tubulin, beta pseudogene 5 |
| UBXN1 | UBX domain protein 1 |
| WIZ | widely interspaced zinc finger motifs |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XIST | X inactive specific transcript (non-protein coding) |
| YIPF2 | Yip1 domain family, member 2 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZC3H11A | zinc finger CCCH-type containing 11A |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF154 | zinc finger protein 154 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ALPK1 | alpha-kinase 1 |
| AR | androgen receptor |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BAG4 | BCL2-associated athanogene 4 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CCDC186 | coiled-coil domain containing 186 |
| CCNT1 | cyclin T1 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CENPC | centromere protein C |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DENND4C | DENN/MADD domain containing 4C |
| DEPDC1 | DEP domain containing 1 |
| DMC1 | DNA meiotic recombinase 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HELLS | helicase, lymphoid-specific |
| HIST1H1E | histone cluster 1, H1e |
| IFT140 | intraflagellar transport 140 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| INCENP | inner centromere protein antigens 135/155kDa |
| IPP | intracisternal A particle-promoted polypeptide |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIAA0556 | KIAA0556 |
| KIAA0894 | KIAA0894 protein |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| METTL16 | methyltransferase like 16 |
| MGC12488 | |
| MPHOSPH8 | M-phase phosphoprotein 8 |
| N4BP3 | NEDD4 binding protein 3 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| PARPBP | PARP1 binding protein |
| PCYOX1 | prenylcysteine oxidase 1 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRR14L | proline rich 14-like |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTK6 | protein tyrosine kinase 6 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RBBP5 | retinoblastoma binding protein 5 |
| RFWD3 | ring finger and WD repeat domain 3 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| SCD5 | stearoyl-CoA desaturase 5 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SPATS2 | spermatogenesis associated, serine-rich 2 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) |
| TBC1D19 | TBC1 domain family, member 19 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM104 | transmembrane protein 104 |
| TRIM16 | tripartite motif containing 16 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) |
| UBQLN4 | ubiquilin 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| USP36 | ubiquitin specific peptidase 36 |
| VASH2 | vasohibin 2 |
| VGF | VGF nerve growth factor inducible |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF254 | zinc finger protein 254 |
| ZNF324 | zinc finger protein 324 |
| ZNF430 | zinc finger protein 430 |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
| ZNF721 | zinc finger protein 721 |
| ZNF91 | zinc finger protein 91 |