cycloserine-6782 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cycloserine-6782 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ALCAM activated leukocyte cell adhesion molecule
ANGEL2 angel homolog 2 (Drosophila)
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGAP26 Rho GTPase activating protein 26
ARMC4 armadillo repeat containing 4
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAAT bile acid CoA:amino acid N-acyltransferase
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BMP2K BMP2 inducible kinase
BTBD2 BTB (POZ) domain containing 2
C17ORF53 chromosome 17 open reading frame 53
C1ORF54 chromosome 1 open reading frame 54
CES1 carboxylesterase 1
COL4A2 collagen, type IV, alpha 2
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DUSP13 dual specificity phosphatase 13
EDN3 endothelin 3
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EIF4E2 eukaryotic translation initiation factor 4E family member 2
EPHB2 EPH receptor B2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
F5 coagulation factor V (proaccelerin, labile factor)
FABP3 fatty acid binding protein 3, muscle and heart
FLNC filamin C, gamma
FOLR3 folate receptor 3 (gamma)
FOXG1 forkhead box G1
FSCN1 fascin actin-bundling protein 1
FSTL1 follistatin-like 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FXYD1 FXYD domain containing ion transport regulator 1
GAB1 GRB2-associated binding protein 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GEMIN7 gem (nuclear organelle) associated protein 7
GFER growth factor, augmenter of liver regeneration
GLB1L galactosidase, beta 1-like
GLIPR1 GLI pathogenesis-related 1
GLRX3 glutaredoxin 3
GRM1 glutamate receptor, metabotropic 1
GSAP gamma-secretase activating protein
GUK1 guanylate kinase 1
HPX hemopexin
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIDINS220 kinase D-interacting substrate, 220kDa
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KRT83 keratin 83, type II
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MINK1 misshapen-like kinase 1
MSR1 macrophage scavenger receptor 1
MTMR7 myotubularin related protein 7
MYLK myosin light chain kinase
NR0B2 nuclear receptor subfamily 0, group B, member 2
NT5DC3 5'-nucleotidase domain containing 3
OASL 2'-5'-oligoadenylate synthetase-like
OTOR otoraplin
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PCDHA9 protocadherin alpha 9
PCDHGA8 protocadherin gamma subfamily A, 8
PIDD1 p53-induced death domain protein 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLXND1 plexin D1
POU5F1B POU class 5 homeobox 1B
PPARD peroxisome proliferator-activated receptor delta
PPP1R17 protein phosphatase 1, regulatory subunit 17
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRKCA protein kinase C, alpha
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RNF122 ring finger protein 122
SAYSD1 SAYSVFN motif domain containing 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEC14L5 SEC14-like 5 (S. cerevisiae)
SENP5 SUMO1/sentrin specific peptidase 5
SF3A2 splicing factor 3a, subunit 2, 66kDa
SFRP4 secreted frizzled-related protein 4
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC12A8 solute carrier family 12, member 8
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLN sarcolipin
SPN sialophorin
STAT2 signal transducer and activator of transcription 2, 113kDa
TGFBR1 transforming growth factor, beta receptor 1
TLR2 toll-like receptor 2
TMEM63A transmembrane protein 63A
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
USP46 ubiquitin specific peptidase 46
WASL Wiskott-Aldrich syndrome-like
WFDC2 WAP four-disulfide core domain 2
ZNF493 zinc finger protein 493
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATF3 activating transcription factor 3
BBS7 Bardet-Biedl syndrome 7
BGLAP bone gamma-carboxyglutamate (gla) protein
C14ORF93 chromosome 14 open reading frame 93
C16ORF59 chromosome 16 open reading frame 59
CAMKMT calmodulin-lysine N-methyltransferase
CAPG capping protein (actin filament), gelsolin-like
CBR4 carbonyl reductase 4
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDC73 cell division cycle 73
CDK20 cyclin-dependent kinase 20
CDT1 chromatin licensing and DNA replication factor 1
CORT cortistatin
CXORF56 chromosome X open reading frame 56
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DSCAM Down syndrome cell adhesion molecule
E2F8 E2F transcription factor 8
ETAA1 Ewing tumor-associated antigen 1
EXOC2 exocyst complex component 2
F8 coagulation factor VIII, procoagulant component
FA2H fatty acid 2-hydroxylase
FAM160B2 family with sequence similarity 160, member B2
FAM189A2 family with sequence similarity 189, member A2
FLCN folliculin
FMO4 flavin containing monooxygenase 4
FXN frataxin
GAB2 GRB2-associated binding protein 2
GAMT guanidinoacetate N-methyltransferase
GBAS glioblastoma amplified sequence
GID4 GID complex subunit 4
GMEB1 glucocorticoid modulatory element binding protein 1
GRB7 growth factor receptor-bound protein 7
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
ICK intestinal cell (MAK-like) kinase
IFT22 intraflagellar transport 22
IL15RA interleukin 15 receptor, alpha
IPP intracisternal A particle-promoted polypeptide
IRF6 interferon regulatory factor 6
IRF9 interferon regulatory factor 9
JMJD4 jumonji domain containing 4
KDM5C lysine (K)-specific demethylase 5C
KIAA0894 KIAA0894 protein
KPTN kaptin (actin binding protein)
LINC00115 long intergenic non-protein coding RNA 115
LPCAT3 lysophosphatidylcholine acyltransferase 3
LYPD3 LY6/PLAUR domain containing 3
LYPLA2P1 lysophospholipase II pseudogene 1
LYRM9 LYR motif containing 9
MAP6D1 MAP6 domain containing 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MED15 mediator complex subunit 15
MNX1 motor neuron and pancreas homeobox 1
MOGS mannosyl-oligosaccharide glucosidase
NDE1 nudE neurodevelopment protein 1
NDRG4 NDRG family member 4
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NIPAL2 NIPA-like domain containing 2
NPIPB15 nuclear pore complex interacting protein family, member B15
PLD2 phospholipase D2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRODH proline dehydrogenase (oxidase) 1
PROS1 protein S (alpha)
RIPK4 receptor-interacting serine-threonine kinase 4
RLN2 relaxin 2
RNF126P1 ring finger protein 126 pseudogene 1
RNF2 ring finger protein 2
RPAP1 RNA polymerase II associated protein 1
SAMHD1 SAM domain and HD domain 1
SERTAD3 SERTA domain containing 3
SGSH N-sulfoglucosamine sulfohydrolase
SIRAL2 SIR2 antiphage like 2
SLC25A44 solute carrier family 25, member 44
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
TMEM104 transmembrane protein 104
TMEM53 transmembrane protein 53
TMUB2 transmembrane and ubiquitin-like domain containing 2
TPST1 tyrosylprotein sulfotransferase 1
TRAPPC2 trafficking protein particle complex 2
TSPAN15 tetraspanin 15
USP27X ubiquitin specific peptidase 27, X-linked
USP6NL USP6 N-terminal like
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
ZBTB39 zinc finger and BTB domain containing 39
ZNF280D zinc finger protein 280D
ZNF329 zinc finger protein 329
ZNF35 zinc finger protein 35
ZNF408 zinc finger protein 408
ZNF442 zinc finger protein 442
ZNF516 zinc finger protein 516
ZNF675 zinc finger protein 675
ZNF696 zinc finger protein 696