cyclothiazide Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

479 genes differentially expressed following the cyclothiazide small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
DHRS2 dehydrogenase/reductase (SDR family) member 2 5.2717
TPM1 tropomyosin 1 (alpha) 5.10107
TMEM50A transmembrane protein 50A 4.88837
GLT8D1 glycosyltransferase 8 domain containing 1 4.81367
SH3YL1 SH3 and SYLF domain containing 1 4.68366
SEPTIN10 septin 10 4.61417
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 4.59675
SNX4 sorting nexin 4 4.54114
CPNE3 copine III 4.39251
SCG5 secretogranin V 4.38439
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 4.35553
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 4.32696
TMEM165 transmembrane protein 165 4.31281
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 4.23391
NCKAP1 NCK-associated protein 1 4.21674
LAPTM4A lysosomal protein transmembrane 4 alpha 4.20732
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 4.16465
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 4.12721
MAP3K13 mitogen-activated protein kinase kinase kinase 13 4.10994
ITM2B integral membrane protein 2B 4.09955
ENOPH1 enolase-phosphatase 1 4.07617
TOP2A topoisomerase (DNA) II alpha 170kDa 4.04723
PSMC3IP PSMC3 interacting protein 4.03293
TSNAX translin-associated factor X 4.01858
NUP54 nucleoporin 54kDa 4.01576
KAZN kazrin, periplakin interacting protein 4.0094
C2CD5 C2 calcium-dependent domain containing 5 4.00758
PHF20 PHD finger protein 20 3.98295
ATF2 activating transcription factor 2 3.98011
BBS10 Bardet-Biedl syndrome 10 3.97215
MAP3K7 mitogen-activated protein kinase kinase kinase 7 3.96181
ADGRB3 adhesion G protein-coupled receptor B3 3.94394
TBPL1 TBP-like 1 3.9289
HNF4A hepatocyte nuclear factor 4, alpha 3.91632
MYL12B myosin, light chain 12B, regulatory 3.90773
AFP alpha-fetoprotein 3.87754
SPAG16 sperm associated antigen 16 3.84901
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor 3.82811
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 3.82321
CENPU centromere protein U 3.81394
PTP4A2 protein tyrosine phosphatase type IVA, member 2 3.80001
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 3.79982
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) 3.79941
UPK3A uroplakin 3A 3.79399
OSBPL8 oxysterol binding protein-like 8 3.79376
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 3.79345
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 3.77864
PDPK1 3-phosphoinositide dependent protein kinase 1 3.76325
TAGLN transgelin 3.75604
PHTF2 putative homeodomain transcription factor 2 3.72796
KCTD12 potassium channel tetramerization domain containing 12 3.72404
ACYP1 acylphosphatase 1, erythrocyte (common) type 3.72215
ORC4 origin recognition complex, subunit 4 3.69694
TBCCD1 TBCC domain containing 1 3.69155
SNTG2 syntrophin, gamma 2 3.68926
CDADC1 cytidine and dCMP deaminase domain containing 1 3.67293
TRAIP TRAF interacting protein 3.66955
FAM131A family with sequence similarity 131, member A 3.66314
ADAM2 ADAM metallopeptidase domain 2 3.66265
ZW10 zw10 kinetochore protein 3.6532
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 3.63225
CTSL cathepsin L 3.61961
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 3.61803
SUB1 SUB1 homolog (S. cerevisiae) 3.61074
VCAM1 vascular cell adhesion molecule 1 3.60845
MXRA7 matrix-remodelling associated 7 3.60526
CCDC15 coiled-coil domain containing 15 3.59815
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 3.59502
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 3.56925
TEX13A testis expressed 13A 3.56624
MYL9 myosin, light chain 9, regulatory 3.56479
CCNC cyclin C 3.56166
SLC25A46 solute carrier family 25, member 46 3.56077
GATA6 GATA binding protein 6 3.54031
ABHD17A abhydrolase domain containing 17A 3.52855
NUP42 nucleoporin 42 3.52612
RAB11A RAB11A, member RAS oncogene family 3.52222
RECQL RecQ helicase-like 3.51754
GPR32 G protein-coupled receptor 32 3.51327
ZNF706 zinc finger protein 706 3.5129
RHBG Rh family, B glycoprotein (gene/pseudogene) 3.51263
CD46 CD46 molecule, complement regulatory protein 3.5126
TRAPPC3 trafficking protein particle complex 3 3.50732
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 3.48182
HMGB2 high mobility group box 2 3.47873
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 3.47432
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 3.45561
NACA4P NACA family member 4, pseudogene 3.44716
DDAH1 dimethylarginine dimethylaminohydrolase 1 3.44194
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 3.43805
H2AZ1 H2A.Z variant histone 1 3.43097
HPF1 histone PARylation factor 1 3.43087
EPB41L2 erythrocyte membrane protein band 4.1-like 2 3.42901
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 3.42409
C12ORF29 chromosome 12 open reading frame 29 3.4216
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 3.42
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 3.41178
ONECUT2 one cut homeobox 2 3.39711
EMP2 epithelial membrane protein 2 3.39704
NEK7 NIMA-related kinase 7 3.3956
ACE2 angiotensin I converting enzyme 2 3.38958
PITX2 paired-like homeodomain 2 3.38865
TBC1D31 TBC1 domain family, member 31 3.38676
SV2C synaptic vesicle glycoprotein 2C 3.37773
ERGIC2 ERGIC and golgi 2 3.37347
STXBP3 syntaxin binding protein 3 3.3682
RPH3A rabphilin 3A 3.36531
SSBP2 single-stranded DNA binding protein 2 3.36151
RAB33B RAB33B, member RAS oncogene family 3.35561
LACTB2 lactamase, beta 2 3.3497
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 3.34369
G0S2 G0/G1 switch 2 3.33159
GLS glutaminase 3.32653
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 3.32515
EFNB1 ephrin-B1 3.32459
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 3.3187
MELK maternal embryonic leucine zipper kinase 3.31686
ETNK2 ethanolamine kinase 2 3.30539
NHLRC2 NHL repeat containing 2 3.2992
TMEM184C transmembrane protein 184C 3.29698
MDRV muscular dystrophy, with rimmed vacuoles 3.29447
DNTT DNA nucleotidylexotransferase 3.29445
SAMD4A sterile alpha motif domain containing 4A 3.29416
BBX bobby sox homolog (Drosophila) 3.29309
BMI1 BMI1 proto-oncogene, polycomb ring finger 3.29261
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 3.28528
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 3.28354
SGCE sarcoglycan, epsilon 3.28149
CBR4 carbonyl reductase 4 3.27517
MAG myelin associated glycoprotein 3.27449
H1-10 H1.10 linker histone 3.2742
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 3.27368
USP33 ubiquitin specific peptidase 33 3.26538
ADGRB2 adhesion G protein-coupled receptor B2 3.26451
ACTL6A actin-like 6A 3.26351
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 3.24934
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 3.24734
ZMIZ1 zinc finger, MIZ-type containing 1 3.22301
GPN3 GPN-loop GTPase 3 3.2229
RHOB ras homolog family member B 3.22204
MINDY3 MINDY lysine 48 deubiquitinase 3 3.22184
VSIG10 V-set and immunoglobulin domain containing 10 3.22002
TRMT61B tRNA methyltransferase 61B 3.21978
ENOX1 ecto-NOX disulfide-thiol exchanger 1 3.21957
TRAPPC4 trafficking protein particle complex 4 3.21349
CRYGC crystallin, gamma C 3.21209
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 3.20865
PNMA2 paraneoplastic Ma antigen 2 3.20138
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 3.20135
FBXO3 F-box protein 3 3.19732
WNT5A wingless-type MMTV integration site family, member 5A 3.19391
RNF11 ring finger protein 11 3.18357
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 3.18286
RMI1 RecQ mediated genome instability 1 3.18256
IFT20 intraflagellar transport 20 3.17312
TRIM37 tripartite motif containing 37 3.17199
PARG poly (ADP-ribose) glycohydrolase 3.16962
INSIG2 insulin induced gene 2 3.16276
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 3.15878
HAPLN1 hyaluronan and proteoglycan link protein 1 3.15529
TRA2B transformer 2 beta homolog (Drosophila) 3.15177
RTN1 reticulon 1 3.14861
SPINK1 serine peptidase inhibitor, Kazal type 1 3.14487
RGS7 regulator of G-protein signaling 7 3.14185
POU3F2 POU class 3 homeobox 2 3.13494
UBE2K ubiquitin-conjugating enzyme E2K 3.12789
COX11 COX11 cytochrome c oxidase copper chaperone 3.12764
AFDN-DT AFDN divergent transcript 3.1275
GPR20 G protein-coupled receptor 20 3.12703
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 3.1232
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene) 3.11788
RRM2 ribonucleotide reductase M2 3.116
CDR2 cerebellar degeneration-related protein 2, 62kDa 3.11165
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 3.11063
PDLIM3 PDZ and LIM domain 3 3.10392
ZC2HC1A zinc finger, C2HC-type containing 1A 3.10346
RAB31 RAB31, member RAS oncogene family 3.10087
RAP2A RAP2A, member of RAS oncogene family 3.10065
MYOD1 myogenic differentiation 1 3.09975
CBX3 chromobox homolog 3 3.09794
TTI1 TELO2 interacting protein 1 3.0952
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 3.09372
RAB29 RAB29, member RAS oncogene family 3.08863
FAM200C family with sequence similarity 200 member C 3.08817
C1ORF109 chromosome 1 open reading frame 109 3.08394
NPAT nuclear protein, ataxia-telangiectasia locus 3.08226
L2HGDH L-2-hydroxyglutarate dehydrogenase 3.07803
C1ORF54 chromosome 1 open reading frame 54 3.07203
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 3.06923
TNNI2 troponin I type 2 (skeletal, fast) 3.06835
BUB3 BUB3 mitotic checkpoint protein 3.06333
GRM3 glutamate receptor, metabotropic 3 3.06154
CES1P1 carboxylesterase 1 pseudogene 1 3.05502
WASL Wiskott-Aldrich syndrome-like 3.04797
HAAO 3-hydroxyanthranilate 3,4-dioxygenase 3.04605
TMEM106B transmembrane protein 106B 3.0436
TUBB4A tubulin, beta 4A class IVa 3.04253
FNTA farnesyltransferase, CAAX box, alpha 3.03206
ISL1 ISL LIM homeobox 1 3.02941
SULT4A1 sulfotransferase family 4A, member 1 3.01991
RAB40B RAB40B, member RAS oncogene family 3.01804
DES desmin 3.00897
HSPB11 heat shock protein family B (small), member 11 3.00551
TMEM14A transmembrane protein 14A 3.00424
DDIT3 DNA-damage-inducible transcript 3 3.00213
SEPTIN2 septin 2 3.00056

decreased expression

Symbol Name Standardized Value
AARS1 alanyl-tRNA synthetase 1 -5.35389
PIAS3 protein inhibitor of activated STAT, 3 -5.26222
PRRC2B proline-rich coiled-coil 2B -5.13839
DPP3 dipeptidyl-peptidase 3 -5.12003
IQGAP1 IQ motif containing GTPase activating protein 1 -4.94361
MDC1 mediator of DNA-damage checkpoint 1 -4.94176
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -4.78245
CASC3 cancer susceptibility candidate 3 -4.76844
GMEB1 glucocorticoid modulatory element binding protein 1 -4.71387
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -4.6854
TRAF3 TNF receptor-associated factor 3 -4.62581
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 -4.57314
TIMELESS timeless circadian clock -4.504
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 -4.47617
ADAM28 ADAM metallopeptidase domain 28 -4.4696
PGM1 phosphoglucomutase 1 -4.42298
ECPAS Ecm29 proteasome adaptor and scaffold -4.40281
MYO5A myosin VA (heavy chain 12, myoxin) -4.38995
ERCC1 excision repair cross-complementation group 1 -4.37511
CERS2 ceramide synthase 2 -4.32895
BECN1 beclin 1, autophagy related -4.30585
TRIP12 thyroid hormone receptor interactor 12 -4.26746
PCNX1 pecanex 1 -4.21718
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -4.21443
RNPEP arginyl aminopeptidase (aminopeptidase B) -4.19965
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 -4.19736
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -4.19665
SCAF8 SR-related CTD-associated factor 8 -4.1883
RRP1B ribosomal RNA processing 1B -4.15823
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 -4.15367
TATDN2 TatD DNase domain containing 2 -4.14035
PEX19 peroxisomal biogenesis factor 19 -4.13067
ZNF208 zinc finger protein 208 -4.12685
PRPF8 pre-mRNA processing factor 8 -4.09836
CHD1L chromodomain helicase DNA binding protein 1-like -4.0887
DHRS9 dehydrogenase/reductase (SDR family) member 9 -4.08092
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) -4.07624
SF3A1 splicing factor 3a, subunit 1, 120kDa -4.06759
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -4.06234
PGD phosphogluconate dehydrogenase -4.04563
ZNF532 zinc finger protein 532 -4.04104
HSPA4 heat shock 70kDa protein 4 -4.0258
HCFC1 host cell factor C1 -4.01288
SRSF4 serine/arginine-rich splicing factor 4 -4.0128
FOXJ2 forkhead box J2 -4.00903
AP2B1 adaptor-related protein complex 2, beta 1 subunit -4.00793
GCN1 GCN1 activator of EIF2AK4 -4.00441
COG4 component of oligomeric golgi complex 4 -3.99709
PBX2P1 pre-B-cell leukemia homeobox 2 pseudogene 1 -3.97886
CS citrate synthase -3.96705
RPL13 ribosomal protein L13 -3.95167
FKBP4 FK506 binding protein 4, 59kDa -3.94996
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -3.92891
GJB5 gap junction protein, beta 5, 31.1kDa -3.89509
POMZP3 POM121 and ZP3 fusion -3.88659
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -3.86004
ERMP1 endoplasmic reticulum metallopeptidase 1 -3.8501
SSRP1 structure specific recognition protein 1 -3.84875
DUSP14 dual specificity phosphatase 14 -3.83657
NUP188 nucleoporin 188kDa -3.82089
NXF2 nuclear RNA export factor 2 -3.81696
PRCP prolylcarboxypeptidase (angiotensinase C) -3.8135
FYCO1 FYVE and coiled-coil domain containing 1 -3.80513
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -3.79908
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -3.79809
PHF10 PHD finger protein 10 -3.79062
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -3.78436
PLD1 phospholipase D1, phosphatidylcholine-specific -3.78385
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 -3.7814
IL4R interleukin 4 receptor -3.77691
CAMSAP1 calmodulin regulated spectrin-associated protein 1 -3.76411
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) -3.75999
FMO2 flavin containing monooxygenase 2 (non-functional) -3.73545
UBAP2L ubiquitin associated protein 2-like -3.73309
NCOR1 nuclear receptor corepressor 1 -3.7188
UBFD1 ubiquitin family domain containing 1 -3.71839
GRB14 growth factor receptor-bound protein 14 -3.71818
FUZ fuzzy planar cell polarity protein -3.70884
TTC4 tetratricopeptide repeat domain 4 -3.70336
FKBP10 FK506 binding protein 10, 65 kDa -3.70144
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) -3.67509
TET3 tet methylcytosine dioxygenase 3 -3.63759
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) -3.62387
KMT2A lysine (K)-specific methyltransferase 2A -3.62283
RBMX RNA binding motif protein, X-linked -3.6175
PRSS23 protease, serine, 23 -3.6156
BRD7 bromodomain containing 7 -3.61166
APOL6 apolipoprotein L, 6 -3.60249
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 -3.59878
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -3.59646
SFPQ splicing factor proline/glutamine-rich -3.5786
EIF4B eukaryotic translation initiation factor 4B -3.55599
ZNF609 zinc finger protein 609 -3.55131
ZNF592 zinc finger protein 592 -3.5482
AVEN apoptosis, caspase activation inhibitor -3.54733
CELF1 CUGBP, Elav-like family member 1 -3.53973
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 -3.53786
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase -3.52694
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A -3.52344
ZNF132 zinc finger protein 132 -3.51616
RBM5 RNA binding motif protein 5 -3.51579
CFAP298 cilia and flagella associated protein 298 -3.51413
ZNF274 zinc finger protein 274 -3.51248
ASXL2 additional sex combs like transcriptional regulator 2 -3.51187
ST7 suppression of tumorigenicity 7 -3.5087
SART1 squamous cell carcinoma antigen recognized by T cells -3.50329
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 -3.50057
KMT2B lysine (K)-specific methyltransferase 2B -3.4973
ILF2 interleukin enhancer binding factor 2 -3.48749
CPA3 carboxypeptidase A3 (mast cell) -3.48728
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -3.4851
SETDB1 SET domain, bifurcated 1 -3.48407
USP24 ubiquitin specific peptidase 24 -3.4806
KDM3B lysine (K)-specific demethylase 3B -3.47771
KLHL12 kelch-like family member 12 -3.46421
HLA-B major histocompatibility complex, class I, B -3.46073
NSD1 nuclear receptor binding SET domain protein 1 -3.45804
PRKDC protein kinase, DNA-activated, catalytic polypeptide -3.44965
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -3.44436
PRSS16 protease, serine, 16 (thymus) -3.42917
CARS1 cysteinyl-tRNA synthetase 1 -3.42844
TMEM156 transmembrane protein 156 -3.41688
VWF von Willebrand factor -3.41396
TNC tenascin C -3.40282
PTPN7 protein tyrosine phosphatase, non-receptor type 7 -3.40014
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -3.39859
THOC6 THO complex 6 -3.39792
KALRN kalirin, RhoGEF kinase -3.38007
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) -3.37872
HLA-DOB major histocompatibility complex, class II, DO beta -3.37615
ATP8B4 ATPase, class I, type 8B, member 4 -3.37026
ENTREP1 endosomal transmembrane epsin interactor 1 -3.36909
YLPM1 YLP motif containing 1 -3.36893
RAB3D RAB3D, member RAS oncogene family -3.36785
NUP98 nucleoporin 98kDa -3.367
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) -3.3606
SNORA21 small nucleolar RNA, H/ACA box 21 -3.35701
RREB1 ras responsive element binding protein 1 -3.35229
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) -3.35061
NFYA nuclear transcription factor Y, alpha -3.34858
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4 -3.34833
SPTBN5 spectrin, beta, non-erythrocytic 5 -3.34701
WDR55 WD repeat domain 55 -3.34636
ZNF516 zinc finger protein 516 -3.34432
PUM1 pumilio RNA-binding family member 1 -3.34318
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A -3.3407
ATF7IP activating transcription factor 7 interacting protein -3.33664
IQCE IQ motif containing E -3.3336
SCRN1 secernin 1 -3.32691
MALT1 MALT1 paracaspase -3.32472
GJC1 gap junction protein, gamma 1, 45kDa -3.32214
CIZ1 CDKN1A interacting zinc finger protein 1 -3.32202
EHMT2 euchromatic histone-lysine N-methyltransferase 2 -3.32119
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10 -3.31989
CD40LG CD40 ligand -3.31649
PLPP1 phospholipid phosphatase 1 -3.31488
NUP133 nucleoporin 133kDa -3.31167
FBL fibrillarin -3.31164
SELP selectin P (granule membrane protein 140kDa, antigen CD62) -3.31108
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 -3.31007
SON SON DNA binding protein -3.30934
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 -3.3082
MYO10 myosin X -3.30034
DCTN5 dynactin 5 (p25) -3.29933
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -3.29615
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) -3.29554
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 -3.29282
AQP1 aquaporin 1 (Colton blood group) -3.28992
DESI1 desumoylating isopeptidase 1 -3.28722
TMPRSS11D transmembrane protease, serine 11D -3.28614
RACK1 receptor for activated C kinase 1 -3.28592
ZNF227 zinc finger protein 227 -3.28404
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -3.283
DUSP4 dual specificity phosphatase 4 -3.28203
POLR1C polymerase (RNA) I polypeptide C, 30kDa -3.27928
EXOSC7 exosome component 7 -3.27621
PRPF3 pre-mRNA processing factor 3 -3.26838
PATZ1 POZ (BTB) and AT hook containing zinc finger 1 -3.26683
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 -3.26678
HOXD11 homeobox D11 -3.26338
CHD7 chromodomain helicase DNA binding protein 7 -3.25942
IL12RB2 interleukin 12 receptor, beta 2 -3.24712
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 -3.24676
MTREX Mtr4 exosome RNA helicase -3.24142
PZP pregnancy-zone protein -3.23838
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -3.2375
TRIM13 tripartite motif containing 13 -3.23051
SEC16A SEC16 homolog A (S. cerevisiae) -3.22973
UXT ubiquitously-expressed, prefoldin-like chaperone -3.22778
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -3.22305
BAG6 BCL2-associated athanogene 6 -3.22259
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -3.222
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -3.21401
ARFIP2 ADP-ribosylation factor interacting protein 2 -3.21122
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -3.20747
ANKFY1 ankyrin repeat and FYVE domain containing 1 -3.20633
IL23A interleukin 23, alpha subunit p19 -3.20606
RPS8 ribosomal protein S8 -3.20062
TERF2 telomeric repeat binding factor 2 -3.20047
DCP1A decapping mRNA 1A -3.19757
RPL3 ribosomal protein L3 -3.1974
ATG7 autophagy related 7 -3.19623
ARNT aryl hydrocarbon receptor nuclear translocator -3.19378
CDK12 cyclin-dependent kinase 12 -3.18888
SEC14L1 SEC14-like 1 (S. cerevisiae) -3.18685
GPI glucose-6-phosphate isomerase -3.17976
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -3.17356
CD8B CD8b molecule -3.17208
SAP30L-AS1 SAP30L antisense RNA 1 (head to head) -3.17193
IFNA10 interferon, alpha 10 -3.16808
DDB1 damage-specific DNA binding protein 1, 127kDa -3.16531
SKAP1 src kinase associated phosphoprotein 1 -3.16508
CES1 carboxylesterase 1 -3.16474
ZBTB5 zinc finger and BTB domain containing 5 -3.16259
INPPL1 inositol polyphosphate phosphatase-like 1 -3.16258
AP1G1 adaptor-related protein complex 1, gamma 1 subunit -3.16224
SRRM1 serine/arginine repetitive matrix 1 -3.16033
VAV1 vav 1 guanine nucleotide exchange factor -3.15895
RBM23 RNA binding motif protein 23 -3.15812
NIPSNAP1 nipsnap homolog 1 (C. elegans) -3.15474
ZNF106 zinc finger protein 106 -3.15186
RGL2 ral guanine nucleotide dissociation stimulator-like 2 -3.15175
IRGQ immunity-related GTPase family, Q -3.15138
MXD1 MAX dimerization protein 1 -3.14645
IPO7 importin 7 -3.14521
NOTCH2 notch 2 -3.14475
PRCC papillary renal cell carcinoma (translocation-associated) -3.13686
CHRDL1 chordin-like 1 -3.13679
BTG2 BTG family, member 2 -3.1332
TRAPPC14 trafficking protein particle complex subunit 14 -3.13227
XPO7 exportin 7 -3.13196
CDT1 chromatin licensing and DNA replication factor 1 -3.13161
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial -3.13139
DDR1 discoidin domain receptor tyrosine kinase 1 -3.1246
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -3.12456
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 -3.12018
TRIM21 tripartite motif containing 21 -3.11463
RGCC regulator of cell cycle -3.11119
ANKHD1 ankyrin repeat and KH domain containing 1 -3.10933
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -3.10645
AHNAK2 AHNAK nucleoprotein 2 -3.10412
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 -3.10318
ZNF134 zinc finger protein 134 -3.10057
ZNF204P zinc finger protein 204, pseudogene -3.09433
RABGGTA Rab geranylgeranyltransferase, alpha subunit -3.09387
SETD5 SET domain containing 5 -3.09231
ARL4C ADP-ribosylation factor-like 4C -3.09137
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -3.08971
GANAB glucosidase, alpha; neutral AB -3.08377
RAD54L2 RAD54-like 2 (S. cerevisiae) -3.07953
ACACA acetyl-CoA carboxylase alpha -3.07722
CDK2 cyclin-dependent kinase 2 -3.07195
RC3H2 ring finger and CCCH-type domains 2 -3.07168
PLA2G2D phospholipase A2, group IID -3.0706
NUP205 nucleoporin 205kDa -3.06598
RUFY1 RUN and FYVE domain containing 1 -3.06533
TRAK2 trafficking protein, kinesin binding 2 -3.0652
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -3.05691
AP3B1 adaptor-related protein complex 3, beta 1 subunit -3.05
ARAF A-Raf proto-oncogene, serine/threonine kinase -3.04707
PROSER1 proline and serine rich 1 -3.04022
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase -3.03893
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) -3.03784
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -3.03498
CBX5 chromobox homolog 5 -3.03496
METTL13 methyltransferase like 13 -3.02215
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 -3.02209
TARS1 threonyl-tRNA synthetase 1 -3.01889
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa -3.01683
NT5DC3 5'-nucleotidase domain containing 3 -3.01182
MARS1 methionyl-tRNA synthetase 1 -3.01169
SRPX sushi-repeat containing protein, X-linked -3.00792
DCAF10 DDB1 and CUL4 associated factor 10 -3.00148