| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the cyproheptadine-2021 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| APP | amyloid beta (A4) precursor protein |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARL1 | ADP-ribosylation factor-like 1 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| BAD | BCL2-associated agonist of cell death |
| BSDC1 | BSD domain containing 1 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAPN3 | calpain 3, (p94) |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCDC94 | coiled-coil domain containing 94 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CCR1 | chemokine (C-C motif) receptor 1 |
| CEP97 | centrosomal protein 97kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CMC4 | C-x(9)-C motif containing 4 |
| COL10A1 | collagen, type X, alpha 1 |
| COL5A3 | collagen, type V, alpha 3 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| DGCR14 | DiGeorge syndrome critical region gene 14 |
| DST | dystonin |
| EHD1 | EH-domain containing 1 |
| ELMO2 | engulfment and cell motility 2 |
| EMP2 | epithelial membrane protein 2 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| ETV5 | ets variant 5 |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| GCAT | glycine C-acetyltransferase |
| GLRX3 | glutaredoxin 3 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GOLGA2 | golgin A2 |
| GPSM3 | G-protein signaling modulator 3 |
| GPX2 | glutathione peroxidase 2 |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HDAC5 | histone deacetylase 5 |
| HDLBP | high density lipoprotein binding protein |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LRRK1 | leucine-rich repeat kinase 1 |
| LTB4R | leukotriene B4 receptor |
| MAPK13 | mitogen-activated protein kinase 13 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MECP2 | methyl CpG binding protein 2 |
| MED27 | mediator complex subunit 27 |
| MICALL1 | MICAL-like 1 |
| MIP | major intrinsic protein of lens fiber |
| MTMR2 | myotubularin related protein 2 |
| MZF1 | myeloid zinc finger 1 |
| NINJ2 | ninjurin 2 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 |
| PIDD1 | p53-induced death domain protein 1 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PITPNA | phosphatidylinositol transfer protein, alpha |
| POLR2J4 | polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma |
| PRODH2 | proline dehydrogenase (oxidase) 2 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| RPS11 | ribosomal protein S11 |
| RRBP1 | ribosome binding protein 1 |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 |
| SLC7A4 | solute carrier family 7, member 4 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SMAD3 | SMAD family member 3 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPATA20 | spermatogenesis associated 20 |
| SPN | sialophorin |
| SRCAP | Snf2-related CREBBP activator protein |
| SSH3 | slingshot protein phosphatase 3 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| TBC1D13 | TBC1 domain family, member 13 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TFE3 | transcription factor binding to IGHM enhancer 3 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEM74B | transmembrane protein 74B |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TNS1 | tensin 1 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| WDR48 | WD repeat domain 48 |
| YIPF2 | Yip1 domain family, member 2 |
| ZNF224 | zinc finger protein 224 |
| ZNF444 | zinc finger protein 444 |
| Symbol | Name |
|---|---|
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ACTL6A | actin-like 6A |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 |
| ANKRD40 | ankyrin repeat domain 40 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARL5A | ADP-ribosylation factor-like 5A |
| ATP8B4 | ATPase, class I, type 8B, member 4 |
| AZI2 | 5-azacytidine induced 2 |
| BPI | bactericidal/permeability-increasing protein |
| BTK | Bruton agammaglobulinemia tyrosine kinase |
| C11ORF68 | chromosome 11 open reading frame 68 |
| CARD9 | caspase recruitment domain family, member 9 |
| CCNE2 | cyclin E2 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| CORO2A | coronin, actin binding protein, 2A |
| CRYL1 | crystallin, lambda 1 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| DCTN4 | dynactin 4 (p62) |
| DENND4A | DENN/MADD domain containing 4A |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DLD | dihydrolipoamide dehydrogenase |
| DNA2 | DNA replication helicase/nuclease 2 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| ERF | Ets2 repressor factor |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| FBXO5 | F-box protein 5 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
| FHL3 | four and a half LIM domains 3 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| FUBP3 | far upstream element (FUSE) binding protein 3 |
| GBAS | glioblastoma amplified sequence |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
| GMCL1 | germ cell-less, spermatogenesis associated 1 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 |
| GPR183 | G protein-coupled receptor 183 |
| HIST1H2BF | histone cluster 1, H2bf |
| HIST1H2BK | histone cluster 1, H2bk |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KIF18A | kinesin family member 18A |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| LIMA1 | LIM domain and actin binding 1 |
| LYZ | lysozyme |
| MCM10 | minichromosome maintenance complex component 10 |
| MEX3C | mex-3 RNA binding family member C |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NDE1 | nudE neurodevelopment protein 1 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NUPL2 | nucleoporin like 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OSBPL11 | oxysterol binding protein-like 11 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial |
| PARG | poly (ADP-ribose) glycohydrolase |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
| PKN1 | protein kinase N1 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RAD51AP1 | RAD51 associated protein 1 |
| RFX7 | regulatory factor X, 7 |
| RPAP3 | RNA polymerase II associated protein 3 |
| RPE | ribulose-5-phosphate-3-epimerase |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RSL24D1 | ribosomal L24 domain containing 1 |
| SECISBP2 | SECIS binding protein 2 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SMAD7 | SMAD family member 7 |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| STXBP3 | syntaxin binding protein 3 |
| SUCO | SUN domain containing ossification factor |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TFEC | transcription factor EC |
| TMEM38B | transmembrane protein 38B |
| TRAPPC11 | trafficking protein particle complex 11 |
| TUBA3C | tubulin, alpha 3c |
| TUBA3D | tubulin, alpha 3d |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| WDR82 | WD repeat domain 82 |
| WEE1 | WEE1 G2 checkpoint kinase |
| ZNF140 | zinc finger protein 140 |
