cyproterone-3545 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the cyproterone-3545 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ABLIM3 actin binding LIM protein family, member 3
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AGRP agouti related neuropeptide
APOC4 apolipoprotein C-IV
ATP10B ATPase, class V, type 10B
BCAM basal cell adhesion molecule (Lutheran blood group)
BTN3A3 butyrophilin, subfamily 3, member A3
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCL27 chemokine (C-C motif) ligand 27
CD72 CD72 molecule
CHGA chromogranin A
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
COL9A3 collagen, type IX, alpha 3
CSNK1G1 casein kinase 1, gamma 1
CST2 cystatin SA
CTAG2 cancer/testis antigen 2
CTSS cathepsin S
CYLD cylindromatosis (turban tumor syndrome)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DCLK2 doublecortin-like kinase 2
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DNAAF1 dynein, axonemal, assembly factor 1
DPEP2 dipeptidase 2
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FASLG Fas ligand (TNF superfamily, member 6)
FBN1 fibrillin 1
FCAR Fc fragment of IgA receptor
FGF4 fibroblast growth factor 4
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GPR15 G protein-coupled receptor 15
GREB1L growth regulation by estrogen in breast cancer-like
GRM3 glutamate receptor, metabotropic 3
HFE hemochromatosis
HIST1H2BM histone cluster 1, H2bm
HNMT histamine N-methyltransferase
HOXA2 homeobox A2
HP haptoglobin
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
IL17A interleukin 17A
IL2 interleukin 2
IMPG2 interphotoreceptor matrix proteoglycan 2
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM5B lysine (K)-specific demethylase 5B
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KLF13 Kruppel-like factor 13
LAMA2 laminin, alpha 2
LDB3 LIM domain binding 3
LEFTY1 left-right determination factor 1
LMF2 lipase maturation factor 2
MAPK11 mitogen-activated protein kinase 11
MLNR motilin receptor
MTCP1 mature T-cell proliferation 1
MTMR7 myotubularin related protein 7
MYOF myoferlin
MYOG myogenin (myogenic factor 4)
NF1 neurofibromin 1
NPC1 Niemann-Pick disease, type C1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OCA2 oculocutaneous albinism II
OSBPL10 oxysterol binding protein-like 10
PAX8 paired box 8
PCSK6 proprotein convertase subtilisin/kexin type 6
PEX3 peroxisomal biogenesis factor 3
PLXNC1 plexin C1
POFUT1 protein O-fucosyltransferase 1
POSTN periostin, osteoblast specific factor
PRTN3 proteinase 3
PTN pleiotrophin
PTPRB protein tyrosine phosphatase, receptor type, B
RAB35 RAB35, member RAS oncogene family
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RGS12 regulator of G-protein signaling 12
SAPCD1 suppressor APC domain containing 1
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SPINT3 serine peptidase inhibitor, Kunitz type, 3
SUGP1 SURP and G patch domain containing 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SYK spleen tyrosine kinase
SYNJ2 synaptojanin 2
TAZ tafazzin
TBX2 T-box 2
TMEM59L transmembrane protein 59-like
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TTC38 tetratricopeptide repeat domain 38
TYMP thymidine phosphorylase
USP22 ubiquitin specific peptidase 22
VCAN versican
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACTL8 actin-like 8
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAM15 ADAM metallopeptidase domain 15
ADCY6 adenylate cyclase 6
ADORA2B adenosine A2b receptor
AKAP12 A kinase (PRKA) anchor protein 12
AR androgen receptor
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASB6 ankyrin repeat and SOCS box containing 6
ATAD3A ATPase family, AAA domain containing 3A
ATP13A2 ATPase type 13A2
BAGE B melanoma antigen
BBS10 Bardet-Biedl syndrome 10
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCORL1 BCL6 corepressor-like 1
C11ORF68 chromosome 11 open reading frame 68
C5 complement component 5
CAPG capping protein (actin filament), gelsolin-like
CBX7 chromobox homolog 7
CD302 CD302 molecule
CDK3 cyclin-dependent kinase 3
CLCN5 chloride channel, voltage-sensitive 5
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
ECI1 enoyl-CoA delta isomerase 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM173A family with sequence similarity 173, member A
FGGY FGGY carbohydrate kinase domain containing
FKBP5 FK506 binding protein 5
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSD1 fibronectin type III and SPRY domain containing 1
FUZ fuzzy planar cell polarity protein
GMPPA GDP-mannose pyrophosphorylase A
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GOLM1 golgi membrane protein 1
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H2BC histone cluster 1, H2bc
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IRF9 interferon regulatory factor 9
KCTD20 potassium channel tetramerization domain containing 20
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LINC00339 long intergenic non-protein coding RNA 339
LPXN leupaxin
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MEFV Mediterranean fever
MFSD10 major facilitator superfamily domain containing 10
MLF2 myeloid leukemia factor 2
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRPL23 mitochondrial ribosomal protein L23
MRPL52 mitochondrial ribosomal protein L52
MYO1E myosin IE
NEK11 NIMA-related kinase 11
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NPDC1 neural proliferation, differentiation and control, 1
NT5C 5', 3'-nucleotidase, cytosolic
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OLFML2A olfactomedin-like 2A
PACS1 phosphofurin acidic cluster sorting protein 1
PARD6A par-6 family cell polarity regulator alpha
PLA2G15 phospholipase A2, group XV
PMM1 phosphomannomutase 1
PTK6 protein tyrosine kinase 6
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PYCRL pyrroline-5-carboxylate reductase-like
RAB5B RAB5B, member RAS oncogene family
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
S100A6 S100 calcium binding protein A6
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH2D4A SH2 domain containing 4A
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC35F6 solute carrier family 35, member F6
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPINK4 serine peptidase inhibitor, Kazal type 4
SREBF1 sterol regulatory element binding transcription factor 1
STK16 serine/threonine kinase 16
TKFC triokinase/FMN cyclase
TMEM134 transmembrane protein 134
TOE1 target of EGR1, member 1 (nuclear)
TRIM25 tripartite motif containing 25
UNC119 unc-119 homolog (C. elegans)
VAX2 ventral anterior homeobox 2
ZFP30 ZFP30 zinc finger protein
ZNF552 zinc finger protein 552
ZNF675 zinc finger protein 675
ZNF696 zinc finger protein 696
ZNHIT2 zinc finger, HIT-type containing 2
ZSCAN26 zinc finger and SCAN domain containing 26