cystic fibrosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description An autosomal recessive disease that is characterized by the buildup of thick, sticky mucus that can damage many organs. (Human Disease Ontology, DOID_1485)
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Genes

505 genes co-occuring with the disease cystic fibrosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 4.92335
DNASE1 deoxyribonuclease I 2.22659
FLNC filamin C, gamma 2.19031
ELANE elastase, neutrophil expressed 2.10904
CLCA1 chloride channel accessory 1 1.84045
CLCA4 chloride channel accessory 4 1.80652
CLCA2 chloride channel accessory 2 1.77496
CXCL8 chemokine (C-X-C motif) ligand 8 1.68272
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type 1.58002
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 1.50535
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.50316
PRSS1 protease, serine, 1 (trypsin 1) 1.48823
SLC26A6 solute carrier family 26 (anion exchanger), member 6 1.44694
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 1.44518
CELA1 chymotrypsin-like elastase family, member 1 1.42674
CELA3B chymotrypsin-like elastase family, member 3B 1.41534
BPI bactericidal/permeability-increasing protein 1.37599
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.34984
DNAH8 dynein, axonemal, heavy chain 8 1.34112
SLC26A3 solute carrier family 26 (anion exchanger), member 3 1.33807
SLPI secretory leukocyte peptidase inhibitor 1.27388
SPINK1 serine peptidase inhibitor, Kazal type 1 1.26081
MUC2 mucin 2, oligomeric mucus/gel-forming 1.26037
INS insulin 1.26037
SLC26A9 solute carrier family 26 (anion exchanger), member 9 1.25384
GOPC golgi-associated PDZ and coiled-coil motif containing 1.24732
ALB albumin 1.24081
PNLIP pancreatic lipase 1.23646
CTSG cathepsin G 1.21868
GLB1 galactosidase, beta 1 1.21738
ANO1 anoctamin 1, calcium activated chloride channel 1.21478
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 1.21219
MPO myeloperoxidase 1.19532
SCNN1B sodium channel, non voltage gated 1 beta subunit 1.18195
TNF tumor necrosis factor 1.17292
SUMF2 sulfatase modifying factor 2 1.16821
CANX calnexin 1.14687
SCNN1G sodium channel, non voltage gated 1 gamma subunit 1.14602
AES amino-terminal enhancer of split 1.14433
MUC3A mucin 3A, cell surface associated 1.14348
TLR5 toll-like receptor 5 1.13797
ALPPL2 alkaline phosphatase, placental-like 2 1.12445
ALPP alkaline phosphatase, placental 1.12403
ALPL alkaline phosphatase, liver/bone/kidney 1.12361
CFP complement factor properdin 1.12193
IL1B interleukin 1, beta 1.11982
LTF lactotransferrin 1.11477
MUC4 mucin 4, cell surface associated 1.09083
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 1.06648
CD79A CD79a molecule, immunoglobulin-associated alpha 1.0627
LCT lactase 1.05976
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 1.05639
CRP C-reactive protein, pentraxin-related 1.03788
NME4 NME/NM23 nucleoside diphosphate kinase 4 1.00752
NME3 NME/NM23 nucleoside diphosphate kinase 3 1.00625
HSPA8 heat shock 70kDa protein 8 1.00288
DEFB1 defensin, beta 1 0.993596
VIP vasoactive intestinal peptide 0.965825
IFRD1 interferon-related developmental regulator 1 0.964148
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.959123
TLR4 toll-like receptor 4 0.956196
S100A8 S100 calcium binding protein A8 0.952438
CAMP cathelicidin antimicrobial peptide 0.94369
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.940364
TLR2 toll-like receptor 2 0.939534
LYZ lysozyme 0.935799
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.925452
PRSS3 protease, serine, 3 0.908553
SFTPD surfactant protein D 0.895
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.882292
CLPS colipase, pancreatic 0.879424
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.868777
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.868368
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.866731
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.862228
PRSS8 protease, serine, 8 0.851992
RNASE3 ribonuclease, RNase A family, 3 0.849536
HHAT hedgehog acyltransferase 0.842982
CCK cholecystokinin 0.837656
REG3A regenerating islet-derived 3 alpha 0.837656
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 0.821257
PRTN3 proteinase 3 0.81018
NCF4 neutrophil cytosolic factor 4, 40kDa 0.787623
SLC26A11 solute carrier family 26 (anion exchanger), member 11 0.785574
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.778613
TJP1 tight junction protein 1 0.77207
TREH trehalase (brush-border membrane glycoprotein) 0.764718
GPER1 G protein-coupled estrogen receptor 1 0.760231
MSH2 mutS homolog 2 0.757786
ADCY10 adenylate cyclase 10 (soluble) 0.755749
ALPI alkaline phosphatase, intestinal 0.75412
IGF1 insulin-like growth factor 1 (somatomedin C) 0.74761
PGM3 phosphoglucomutase 3 0.746391
KRT13 keratin 13, type I 0.739488
CXCR1 chemokine (C-X-C motif) receptor 1 0.732596
S100A9 S100 calcium binding protein A9 0.730571
CLCN2 chloride channel, voltage-sensitive 2 0.728143
CLCN3 chloride channel, voltage-sensitive 3 0.720865
CXCR2 chemokine (C-X-C motif) receptor 2 0.720865
ANPEP alanyl (membrane) aminopeptidase 0.712392
CTRC chymotrypsin C (caldecrin) 0.704742
GSN gelsolin 0.704742
TF transferrin 0.703536
MUC7 mucin 7, secreted 0.703134
PLCB2 phospholipase C, beta 2 0.699919
TOB1 transducer of ERBB2, 1 0.695504
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.693098
MYD88 myeloid differentiation primary response 88 0.689893
CFAP57 cilia and flagella associated protein 57 0.689492
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.686691
ITPK1 inositol-tetrakisphosphate 1-kinase 0.679499
GUSB glucuronidase, beta 0.672324
GUCY2C guanylate cyclase 2C 0.667947
GGT1 gamma-glutamyltransferase 1 0.663181
LPO lactoperoxidase 0.662784
CLNK cytokine-dependent hematopoietic cell linker 0.661197
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.660404
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 0.660008
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.65288
KRT18 keratin 18, type I 0.652484
MPI mannose phosphate isomerase 0.652089
KCNK5 potassium channel, two pore domain subfamily K, member 5 0.650113
BGLAP bone gamma-carboxyglutamate (gla) protein 0.646165
UMOD uromodulin 0.644981
CNTN3 contactin 3 (plasmacytoma associated) 0.644586
BEST1 bestrophin 1 0.641433
MARCKS myristoylated alanine-rich protein kinase C substrate 0.641039
SGK1 serum/glucocorticoid regulated kinase 1 0.633563
LY96 lymphocyte antigen 96 0.62728
GNAT3 guanine nucleotide binding protein, alpha transducing 3 0.62728
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.624927
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.624143
MUC1 mucin 1, cell surface associated 0.622575
CXCL2 chemokine (C-X-C motif) ligand 2 0.622575
CCL17 chemokine (C-C motif) ligand 17 0.619051
HSPA4 heat shock 70kDa protein 4 0.616312
KNG1 kininogen 1 0.612401
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.610057
PLA2G5 phospholipase A2, group V 0.604981
MGAM maltase-glucoamylase 0.60303
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.596012
NPR1 natriuretic peptide receptor 1 0.595233
CD4 CD4 molecule 0.590948
IL6 interleukin 6 0.590169
TGFB1 transforming growth factor, beta 1 0.587833
RNASEH2A ribonuclease H2, subunit A 0.577716
PLCZ1 phospholipase C, zeta 1 0.577327
DEFB106A defensin, beta 106A 0.574605
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.573828
PPY pancreatic polypeptide 0.573828
SFTPA1 surfactant protein A1 0.57305
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.569941
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.567609
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.56722
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.5645
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.562946
SFTPA2 surfactant protein A2 0.561392
FOXJ1 forkhead box J1 0.558285
SVIP small VCP/p97-interacting protein 0.55712
HSH2D hematopoietic SH2 domain containing 0.554015
PLA2G2C phospholipase A2, group IIC 0.551686
ADCY2 adenylate cyclase 2 (brain) 0.544318
PDZD3 PDZ domain containing 3 0.543155
LGALS7 lectin, galactoside-binding, soluble, 7 0.541992
PTGR1 prostaglandin reductase 1 0.541605
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.541217
ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 0.541217
IL9R interleukin 9 receptor 0.538118
SLC26A8 solute carrier family 26 (anion exchanger), member 8 0.536957
SBDS Shwachman-Bodian-Diamond syndrome 0.536183
LAP3 leucine aminopeptidase 3 0.534635
MRPS7 mitochondrial ribosomal protein S7 0.532701
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 0.531541
IGFBP3 insulin-like growth factor binding protein 3 0.531541
CAT catalase 0.531154
AFP alpha-fetoprotein 0.528449
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.522273
PHF12 PHD finger protein 12 0.515725
DEFB4A defensin, beta 4A 0.513417
SEC24B SEC24 family member B 0.508041
TMPRSS15 transmembrane protease, serine 15 0.507273
MBL2 mannose-binding lectin (protein C) 2, soluble 0.50459
SFTPB surfactant protein B 0.500379
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 0.499997
SEC24A SEC24 family member A 0.499997
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.499614
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.499231
CLEC19A C-type lectin domain family 19, member A 0.495793
MMP9 matrix metallopeptidase 9 0.494648
TTR transthyretin 0.491978
SI sucrase-isomaltase (alpha-glucosidase) 0.491215
GIP gastric inhibitory polypeptide 0.490835
MRPL49 mitochondrial ribosomal protein L49 0.48893
RND3 Rho family GTPase 3 0.482464
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 0.482084
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 0.480186
CALU calumenin 0.479047
ADSL adenylosuccinate lyase 0.479047
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.479047
HBE1 hemoglobin, epsilon 1 0.47374
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 0.472225
SOD2 superoxide dismutase 2, mitochondrial 0.46655
HBA2 hemoglobin, alpha 2 0.464283
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.462394
TOM1 target of myb1 (chicken) 0.459751
ADRB2 adrenoceptor beta 2, surface 0.459751
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 0.458996
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.458241
COL1A2 collagen, type I, alpha 2 0.457864
CPA6 carboxypeptidase A6 0.457109
PDZK1 PDZ domain containing 1 0.456732
RHOQ ras homolog family member Q 0.455601
ICK intestinal cell (MAK-like) kinase 0.453716
BPIFA1 BPI fold containing family A, member 1 0.452208
ERLEC1 endoplasmic reticulum lectin 1 0.449194
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.445805
ANO2 anoctamin 2, calcium activated chloride channel 0.445052
DCLK3 doublecortin-like kinase 3 0.444676
TIMP1 TIMP metallopeptidase inhibitor 1 0.443171
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 0.441666
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 0.441666
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase) 0.44129
SLC26A5 solute carrier family 26 (anion exchanger), member 5 0.439786
GC group-specific component (vitamin D binding protein) 0.439034
COPE coatomer protein complex, subunit epsilon 0.436778
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.434148
ANO6 anoctamin 6 0.433772
GSTA1 glutathione S-transferase alpha 1 0.430017
ICAM1 intercellular adhesion molecule 1 0.428516
LAMP1 lysosomal-associated membrane protein 1 0.428516
SFTA3 surfactant associated 3 0.42814
IL10 interleukin 10 0.423265
GP2 glycoprotein 2 (zymogen granule membrane) 0.423265
FPR2 formyl peptide receptor 2 0.422515
PON1 paraoxonase 1 0.420266
GPX5 glutathione peroxidase 5 0.419892
GPX4 glutathione peroxidase 4 0.416896
ANXA1 annexin A1 0.415398
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.413153
PTH parathyroid hormone 0.412405
MUC17 mucin 17, cell surface associated 0.410535
GSTA3 glutathione S-transferase alpha 3 0.407545
F2 coagulation factor II (thrombin) 0.406798
GSTA2 glutathione S-transferase alpha 2 0.406425
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.406051
CCL2 chemokine (C-C motif) ligand 2 0.405678
GSTA4 glutathione S-transferase alpha 4 0.405305
IL1A interleukin 1, alpha 0.403811
AQP5 aquaporin 5 0.401572
GPX1 glutathione peroxidase 1 0.401572
CSN1S1 casein alpha s1 0.40008
VDAC1 voltage-dependent anion channel 1 0.40008
FTH1 ferritin, heavy polypeptide 1 0.399334
FTL ferritin, light polypeptide 0.399334
TNS4 tensin 4 0.398962
UBXN1 UBX domain protein 1 0.398216
GCG glucagon 0.396725
LIG3 ligase III, DNA, ATP-dependent 0.396725
S100A10 S100 calcium binding protein A10 0.396353
AKAP7 A kinase (PRKA) anchor protein 7 0.396353
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.394863
S100A12 S100 calcium binding protein A12 0.393746
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.389653
PIAS1 protein inhibitor of activated STAT, 1 0.389281
MYO5C myosin VC 0.388909
FEN1 flap structure-specific endonuclease 1 0.388538
HDAC2 histone deacetylase 2 0.388166
AMBP alpha-1-microglobulin/bikunin precursor 0.387794
PANX1 pannexin 1 0.387794
RIPK4 receptor-interacting serine-threonine kinase 4 0.385193
NELFCD negative elongation factor complex member C/D 0.383708
PYCR1 pyrroline-5-carboxylate reductase 1 0.382966
TRDN triadin 0.379997
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 0.379256
LRRC26 leucine rich repeat containing 26 0.379256
HP haptoglobin 0.377031
RHD Rh blood group, D antigen 0.376661
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.374809
ACTB actin, beta 0.371847
HPR haptoglobin-related protein 0.371107
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.371107
PIGR polymeric immunoglobulin receptor 0.370737
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.368888
NOS2 nitric oxide synthase 2, inducible 0.368888
RPL3 ribosomal protein L3 0.367779
DCTN4 dynactin 4 (p62) 0.364454
ANO9 anoctamin 9 0.364085
ACT actin-like protein (ACT) gene 0.364085
AP1M1 adaptor-related protein complex 1, mu 1 subunit 0.362609
CPB1 carboxypeptidase B1 (tissue) 0.361133
SMAD3 SMAD family member 3 0.35892
CES1 carboxylesterase 1 0.358551
FUT2 fucosyltransferase 2 (secretor status included) 0.357077
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 0.355972
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.352291
RND1 Rho family GTPase 1 0.351555
IGLC3 immunoglobulin lambda constant 3 (Kern-Oz+ marker) 0.350452
ACTG1 actin gamma 1 0.342372
POTEF POTE ankyrin domain family, member F 0.342006
KCNT2 potassium channel, sodium activated subfamily T, member 2 0.341272
SYTL5 synaptotagmin-like 5 0.340173
POTEI POTE ankyrin domain family, member I 0.33944
ARSB arylsulfatase B 0.33944
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.33651
STX1A syntaxin 1A (brain) 0.335046
CISD1 CDGSH iron sulfur domain 1 0.333949
CA2 carbonic anhydrase II 0.331025
RHCE Rh blood group, CcEe antigens 0.331025
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3 0.3292
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 0.328834
FN1 fibronectin 1 0.323002
CALCOCO2 calcium binding and coiled-coil domain 2 0.322273
SLC26A4 solute carrier family 26 (anion exchanger), member 4 0.317545
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.317545
ART5 ADP-ribosyltransferase 5 0.316819
MLN motilin 0.316456
STIM1 stromal interaction molecule 1 0.316092
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 0.315729
GJC1 gap junction protein, gamma 1, 45kDa 0.315003
TSPO translocator protein (18kDa) 0.315003
COX5A cytochrome c oxidase subunit Va 0.315003
CCP110 centriolar coiled coil protein 110kDa 0.31464
CTTNBP2 cortactin binding protein 2 0.314278
CA12 carbonic anhydrase XII 0.313915
WDFY2 WD repeat and FYVE domain containing 2 0.313189
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 0.312464
GSR glutathione reductase 0.311014
SPDEF SAM pointed domain containing ETS transcription factor 0.31029
ADCY8 adenylate cyclase 8 (brain) 0.309204
TXN thioredoxin 0.308118
DEFB103A defensin, beta 103A 0.308118
RSPH9 radial spoke head 9 homolog (Chlamydomonas) 0.307757
SARS seryl-tRNA synthetase 0.306672
LBP lipopolysaccharide binding protein 0.30631
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.305226
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 0.302337
OCLN occludin 0.302337
UBC ubiquitin C 0.298011
TUB tubby bipartite transcription factor 0.298011
COMMD1 copper metabolism (Murr1) domain containing 1 0.296931
SHKBP1 SH3KBP1 binding protein 1 0.294053
MLH1 mutL homolog 1 0.293694
SMN2 survival of motor neuron 2, centromeric 0.293334
KEL Kell blood group, metallo-endopeptidase 0.292257
CAV1 caveolin 1, caveolae protein, 22kDa 0.289744
PKM pyruvate kinase, muscle 0.287235
DEFB103B defensin, beta 103B 0.286877
HOOK2 hook microtubule-tethering protein 2 0.286519
TLR1 toll-like receptor 1 0.282225
CREB1 cAMP responsive element binding protein 1 0.280796
UGDH UDP-glucose 6-dehydrogenase 0.280082
HDAC9 histone deacetylase 9 0.279011
SMN1 survival of motor neuron 1, telomeric 0.278297
CTSS cathepsin S 0.27794
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.276514
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.276158
TGM2 transglutaminase 2 0.275445
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.274021
PLA2G1B phospholipase A2, group IB (pancreas) 0.272953
CP ceruloplasmin (ferroxidase) 0.272597
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.269398
SZRD1 SUZ RNA binding domain containing 1 0.267267
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.267267
AMELY amelogenin, Y-linked 0.264431
GSTP1 glutathione S-transferase pi 1 0.263722
FBXO17 F-box protein 17 0.263368
GSTM1 glutathione S-transferase mu 1 0.263014
CXCL10 chemokine (C-X-C motif) ligand 10 0.261599
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.260891
CARD17 caspase recruitment domain family, member 17 0.25983
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.259124
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.25877
ETV3 ets variant 3 0.257711
CLDN1 claudin 1 0.257005
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.253127
SQSTM1 sequestosome 1 0.252422
EHF ets homologous factor 0.252422
EEA1 early endosome antigen 1 0.25207
FAM120B family with sequence similarity 120B 0.251718
TARM1 T cell-interacting, activating receptor on myeloid cells 1 0.251718
ARRB1 arrestin, beta 1 0.251015
PACS2 phosphofurin acidic cluster sorting protein 2 0.249257
HMGB1 high mobility group box 1 0.248554
ASIC2 acid sensing (proton gated) ion channel 2 0.247501
SEC24D SEC24 family member D 0.246799
CTSC cathepsin C 0.246799
MASP2 mannan-binding lectin serine peptidase 2 0.245747
UBB ubiquitin B 0.245396
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.244696
HDAC7 histone deacetylase 7 0.244696
MMP7 matrix metallopeptidase 7 0.244345
CLDN7 claudin 7 0.244345
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.243295
MRI1 methylthioribose-1-phosphate isomerase 1 0.242245
F13B coagulation factor XIII, B polypeptide 0.241546
DEFB106B defensin, beta 106B 0.241196
PDE5A phosphodiesterase 5A, cGMP-specific 0.239799
LEP leptin 0.23945
SRI sorcin 0.239101
UBE2S ubiquitin-conjugating enzyme E2S 0.238403
GORASP2 golgi reassembly stacking protein 2, 55kDa 0.237009
ADRA1D adrenoceptor alpha 1D 0.235964
HK1 hexokinase 1 0.235616
AMELX amelogenin, X-linked 0.235268
SLC36A3 solute carrier family 36, member 3 0.235268
MUC6 mucin 6, oligomeric mucus/gel-forming 0.233878
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 0.231795
VIM vimentin 0.231448
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.231448
MMP12 matrix metallopeptidase 12 0.22937
F5 coagulation factor V (proaccelerin, labile factor) 0.228679
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12 0.227297
CCL3 chemokine (C-C motif) ligand 3 0.225573
RBP3 retinol binding protein 3, interstitial 0.225229
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.224196
TOLLIP toll interacting protein 0.223853
TCF3 transcription factor 3 0.223165
SCTR secretin receptor 0.222822
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.220766
DUOX1 dual oxidase 1 0.220424
HBD hemoglobin, delta 0.220424
EGF epidermal growth factor 0.220424
DGKI diacylglycerol kinase, iota 0.218715
TAC1 tachykinin, precursor 1 0.217693
IL4 interleukin 4 0.217012
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 0.216672
RBM23 RNA binding motif protein 23 0.216332
CAMK1 calcium/calmodulin-dependent protein kinase I 0.213621
ADCY1 adenylate cyclase 1 (brain) 0.212945
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 0.212945
AZU1 azurocidin 1 0.212945
DERL1 derlin 1 0.212608
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.210925
ANXA4 annexin A4 0.210253
HBB hemoglobin, beta 0.210253
VAMP3 vesicle-associated membrane protein 3 0.209918
TCTEX1D4 Tctex1 domain containing 4 0.208579
SEPT8 septin 8 0.207578
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.207245
PPARG peroxisome proliferator-activated receptor gamma 0.20658
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.204923
SGCZ sarcoglycan, zeta 0.203604
XBP1 X-box binding protein 1 0.203604
NKRF NFKB repressing factor 0.201962
RAD50 RAD50 homolog (S. cerevisiae) 0.199356
APIP APAF1 interacting protein 0.198709
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.198386
GGT2 gamma-glutamyltransferase 2 0.196139
CTSB cathepsin B 0.19582
SLC4A9 solute carrier family 4, sodium bicarbonate cotransporter, member 9 0.195183
C5AR1 complement component 5a receptor 1 0.194865
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.193915
TLK2 tousled-like kinase 2 0.193915
DCTD dCMP deaminase 0.193285
CUBN cubilin (intrinsic factor-cobalamin receptor) 0.193285
TFRC transferrin receptor 0.193285
AGER advanced glycosylation end product-specific receptor 0.192971
CCL20 chemokine (C-C motif) ligand 20 0.188632
PARP1 poly (ADP-ribose) polymerase 1 0.188326
AQP9 aquaporin 9 0.187719
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 0.187113
IL17A interleukin 17A 0.186811
SFTPC surfactant protein C 0.183835
ARHGAP18 Rho GTPase activating protein 18 0.18151
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.180652
LCN2 lipocalin 2 0.180367
KAT8 K(lysine) acetyltransferase 8 0.180367
TSKU tsukushi, small leucine rich proteoglycan 0.178126
TREM1 triggering receptor expressed on myeloid cells 1 0.178126
EGFR epidermal growth factor receptor 0.177029
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.176757
IPO13 importin 13 0.175679
STAT1 signal transducer and activator of transcription 1, 91kDa 0.173314
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.172038
GRP gastrin-releasing peptide 0.171535
DNASE2B deoxyribonuclease II beta 0.170299
MET MET proto-oncogene, receptor tyrosine kinase 0.170054
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.169812
DMBT1 deleted in malignant brain tumors 1 0.169812
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.169812
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5 0.169571
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 0.16933
ANXA5 annexin A5 0.167682
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.167682
BECN1 beclin 1, autophagy related 0.166995
EZR ezrin 0.166995
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.165655
DEFA4 defensin, alpha 4, corticostatin 0.165217
DMD dystrophin 0.165001
C3 complement component 3 0.165001
ANO10 anoctamin 10 0.163938
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.163729
ST20 suppressor of tumorigenicity 20 0.163729
IL2RA interleukin 2 receptor, alpha 0.163317
RPS27A ribosomal protein S27a 0.163317
WNK4 WNK lysine deficient protein kinase 4 0.162908
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 0.162707
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 0.162505
PAH phenylalanine hydroxylase 0.160203
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.159302
MUC12 mucin 12, cell surface associated 0.158605
ADA adenosine deaminase 0.158434
SOCS2 suppressor of cytokine signaling 2 0.158266
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.157929
STX5 syntaxin 5 0.157929