| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the cytisine-1766 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APP | amyloid beta (A4) precursor protein |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa |
| ARTN | artemin |
| ASPH | aspartate beta-hydroxylase |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATF6B | activating transcription factor 6 beta |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| BCAN | brevican |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BRCA2 | breast cancer 2, early onset |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CALR | calreticulin |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CCL23 | chemokine (C-C motif) ligand 23 |
| CDK10 | cyclin-dependent kinase 10 |
| CIITA | class II, major histocompatibility complex, transactivator |
| CREM | cAMP responsive element modulator |
| DEAF1 | DEAF1 transcription factor |
| DEPDC1 | DEP domain containing 1 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DUS2 | dihydrouridine synthase 2 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 |
| EIF5B | eukaryotic translation initiation factor 5B |
| ENAH | enabled homolog (Drosophila) |
| ERO1L | ERO1-like (S. cerevisiae) |
| EXOG | endo/exonuclease (5'-3'), endonuclease G-like |
| FSCN1 | fascin actin-bundling protein 1 |
| FZD5 | frizzled class receptor 5 |
| GNS | glucosamine (N-acetyl)-6-sulfatase |
| HIRA | histone cell cycle regulator |
| ICAM1 | intercellular adhesion molecule 1 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IFITM3 | interferon induced transmembrane protein 3 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| INTS5 | integrator complex subunit 5 |
| ITGB5 | integrin, beta 5 |
| JAG2 | jagged 2 |
| KIF24 | kinesin family member 24 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KLF13 | Kruppel-like factor 13 |
| LSM12 | LSM12 homolog (S. cerevisiae) |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| MAGED2 | melanoma antigen family D2 |
| MANEA | mannosidase, endo-alpha |
| MED18 | mediator complex subunit 18 |
| MED7 | mediator complex subunit 7 |
| MED9 | mediator complex subunit 9 |
| MEF2A | myocyte enhancer factor 2A |
| MISP | mitotic spindle positioning |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MYL10 | myosin, light chain 10, regulatory |
| NCOA3 | nuclear receptor coactivator 3 |
| NDRG2 | NDRG family member 2 |
| NELL2 | NEL-like 2 (chicken) |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
| NXF2 | nuclear RNA export factor 2 |
| OSBPL2 | oxysterol binding protein-like 2 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| POU2F1 | POU class 2 homeobox 1 |
| PPP6R2 | protein phosphatase 6, regulatory subunit 2 |
| PRR4 | proline rich 4 (lacrimal) |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RANBP3 | RAN binding protein 3 |
| RITA1 | RBPJ interacting and tubulin associated 1 |
| RRBP1 | ribosome binding protein 1 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SAPCD1 | suppressor APC domain containing 1 |
| SBF1 | SET binding factor 1 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIRT3 | sirtuin 3 |
| SIRT5 | sirtuin 5 |
| SMAD6 | SMAD family member 6 |
| SMIM8 | small integral membrane protein 8 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNTA1 | syntrophin, alpha 1 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| STK16 | serine/threonine kinase 16 |
| SUGP1 | SURP and G patch domain containing 1 |
| TGM5 | transglutaminase 5 |
| TMED7 | transmembrane emp24 protein transport domain containing 7 |
| TMEM186 | transmembrane protein 186 |
| TRIM14 | tripartite motif containing 14 |
| TSC22D2 | TSC22 domain family, member 2 |
| TUBB3 | tubulin, beta 3 class III |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF419 | zinc finger protein 419 |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| B3GNT1 | |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C3 | complement component 3 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC64 | coiled-coil domain containing 64 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCS | copper chaperone for superoxide dismutase |
| CD101 | CD101 molecule |
| CD82 | CD82 molecule |
| CDCP1 | CUB domain containing protein 1 |
| CENPQ | centromere protein Q |
| CETN1 | centrin, EF-hand protein, 1 |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTAGE9 | CTAGE family, member 9 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| ECM1 | extracellular matrix protein 1 |
| ESYT1 | extended synaptotagmin-like protein 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FAM189B | family with sequence similarity 189, member B |
| FANCF | Fanconi anemia, complementation group F |
| FCHSD2 | FCH and double SH3 domains 2 |
| FPGS | folylpolyglutamate synthase |
| GPATCH2 | G patch domain containing 2 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| HDAC5 | histone deacetylase 5 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IFNA17 | interferon, alpha 17 |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIAA0894 | KIAA0894 protein |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 |
| LILRB4 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 |
| LUC7L | LUC7-like (S. cerevisiae) |
| LXN | latexin |
| MAGEF1 | melanoma antigen family F1 |
| MBTD1 | mbt domain containing 1 |
| MON1B | MON1 secretory trafficking family member B |
| MTMR14 | myotubularin related protein 14 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MXRA8 | matrix-remodelling associated 8 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCD1 | phospholipase C, delta 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
| PRCC | papillary renal cell carcinoma (translocation-associated) |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| QRICH1 | glutamine-rich 1 |
| RAB17 | RAB17, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| SIRT6 | sirtuin 6 |
| SLC35E3 | solute carrier family 35, member E3 |
| SNX15 | sorting nexin 15 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SSFA2 | sperm specific antigen 2 |
| STAC | SH3 and cysteine rich domain |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| SYT13 | synaptotagmin XIII |
| THUMPD2 | THUMP domain containing 2 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM11 | transmembrane protein 11 |
| TMEM246 | transmembrane protein 246 |
| TMEM53 | transmembrane protein 53 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRIM25 | tripartite motif containing 25 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TXLNA | taxilin alpha |
| UPB1 | ureidopropionase, beta |
| VILL | villin-like |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XPC | xeroderma pigmentosum, complementation group C |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF282 | zinc finger protein 282 |
| ZNF510 | zinc finger protein 510 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
