| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the cytisine-5739 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AK5 | adenylate kinase 5 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| AMACR | alpha-methylacyl-CoA racemase |
| ARHGAP28 | Rho GTPase activating protein 28 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARSD | arylsulfatase D |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATXN2L | ataxin 2-like |
| B9D1 | B9 protein domain 1 |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BGN | biglycan |
| BMPR1B | bone morphogenetic protein receptor, type IB |
| C14ORF105 | chromosome 14 open reading frame 105 |
| CBS | cystathionine-beta-synthase |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CD93 | CD93 molecule |
| CDH8 | cadherin 8, type 2 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHI3L2 | chitinase 3-like 2 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| COMMD4 | COMM domain containing 4 |
| COMT | catechol-O-methyltransferase |
| CORO7 | coronin 7 |
| CPZ | carboxypeptidase Z |
| CRB1 | crumbs family member 1, photoreceptor morphogenesis associated |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
| EPYC | epiphycan |
| FHL3 | four and a half LIM domains 3 |
| FOXG1 | forkhead box G1 |
| FRMD1 | FERM domain containing 1 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GPC3 | glypican 3 |
| GPM6A | glycoprotein M6A |
| HAL | histidine ammonia-lyase |
| HSF1 | heat shock transcription factor 1 |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| KHSRP | KH-type splicing regulatory protein |
| KIAA0040 | KIAA0040 |
| KIAA1109 | KIAA1109 |
| KIAA1456 | KIAA1456 |
| KIF1C | kinesin family member 1C |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LUZP4 | leucine zipper protein 4 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MINK1 | misshapen-like kinase 1 |
| MLANA | melan-A |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MTSS1L | metastasis suppressor 1-like |
| MUC3B | mucin 3B, cell surface associated |
| MYO1F | myosin IF |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NF1 | neurofibromin 1 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRL | neural retina leucine zipper |
| ONECUT2 | one cut homeobox 2 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PAX8 | paired box 8 |
| PDE5A | phosphodiesterase 5A, cGMP-specific |
| PER2 | period circadian clock 2 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB26 | RAB26, member RAS oncogene family |
| RAD51B | RAD51 paralog B |
| RGS5 | regulator of G-protein signaling 5 |
| RND1 | Rho family GTPase 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RUNX1 | runt-related transcription factor 1 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SOCS3 | suppressor of cytokine signaling 3 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| STK16 | serine/threonine kinase 16 |
| TBCD | tubulin folding cofactor D |
| THBD | thrombomodulin |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TMEM19 | transmembrane protein 19 |
| TMEM246 | transmembrane protein 246 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| UST | uronyl-2-sulfotransferase |
| VGLL3 | vestigial-like family member 3 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BCL2L2 | BCL2-like 2 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1RL | complement component 1, r subcomponent-like |
| CDIP1 | cell death-inducing p53 target 1 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRYBA2 | crystallin, beta A2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DDN | dendrin |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DUSP8 | dual specificity phosphatase 8 |
| EFNB1 | ephrin-B1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM184A | family with sequence similarity 184, member A |
| FBRS | fibrosin |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO2 | F-box protein 2 |
| GAB2 | GRB2-associated binding protein 2 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HIST1H2BM | histone cluster 1, H2bm |
| HIST1H3G | histone cluster 1, H3g |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL17RB | interleukin 17 receptor B |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IL7 | interleukin 7 |
| KIAA0754 | KIAA0754 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LIPG | lipase, endothelial |
| LOC257152 | uncharacterized LOC257152 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MGC12488 | |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MXD3 | MAX dimerization protein 3 |
| MYL5 | myosin, light chain 5, regulatory |
| MYL9 | myosin, light chain 9, regulatory |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PALMD | palmdelphin |
| PARD6A | par-6 family cell polarity regulator alpha |
| PER3 | period circadian clock 3 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PTK6 | protein tyrosine kinase 6 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RNF122 | ring finger protein 122 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SDC3 | syndecan 3 |
| SH2D2A | SH2 domain containing 2A |
| SIRT2 | sirtuin 2 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMA4 | glucuronidase, beta pseudogene |
| SND1-IT1 | SND1 intronic transcript 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TENM1 | teneurin transmembrane protein 1 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMEM132A | transmembrane protein 132A |
| TRIM25 | tripartite motif containing 25 |
| TUBA3C | tubulin, alpha 3c |
| UBTD1 | ubiquitin domain containing 1 |
| WDR78 | WD repeat domain 78 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZNF276 | zinc finger protein 276 |
| ZNF747 | zinc finger protein 747 |
| ZNF768 | zinc finger protein 768 |
| ZNF816 | zinc finger protein 816 |