cytolytic granule Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description A specialized secretory lysosome that is present in cells with cytolytic capability such as cytotoxic T lymphocytes and natural killer cells. Cytolytic granules mediate the storage and regulated excretion of lytic molecules for killing of target cells. (Gene Ontology, GO_0044194)
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4 proteins localized to the cytolytic granule cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
LAMP1 lysosomal-associated membrane protein 1
PRF1 perforin 1 (pore forming protein)
RNF19B ring finger protein 19B
STXBP2 syntaxin binding protein 2