cytolytic granule Gene Set

Dataset	GO Cellular Component Annotations 2023
Category	structural or functional annotations
Type	biological process
Description	A specialized secretory lysosome that is present in cells with cytolytic capability such as cytotoxic T lymphocytes and natural killer cells. Cytolytic granules mediate the storage and regulated excretion of lytic molecules for killing of target cells. (Gene Ontology, GO_0044194)
External Link	http://amigo.geneontology.org/amigo/term/GO:0044194
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Genes

8 proteins localized to the cytolytic granule cellular component from the curated GO Cellular Component Annotations 2023 dataset.

Symbol	Name
ARL8B	ADP-ribosylation factor-like 8B
GNLY	granulysin
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
LAMP1	lysosomal-associated membrane protein 1
NKG7	natural killer cell granule protein 7
PRF1	perforin 1 (pore forming protein)
RNF19B	ring finger protein 19B
STXBP2	syntaxin binding protein 2