| Dataset | GO Cellular Component Annotations 2025 |
| Category | structural or functional annotations |
| Type | cellular component |
| Description | A specialized secretory lysosome that is present in cells with cytolytic capability such as cytotoxic T lymphocytes and natural killer cells. Cytolytic granules mediate the storage and regulated excretion of lytic molecules for killing of target cells. (Gene Ontology, GO_0044194) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0044194 |
| Similar Terms | |
| Downloads & Tools |
8 proteins localized to the cytolytic granule cellular component from the curated GO Cellular Component Annotations 2025 dataset.
| Symbol | Name |
|---|---|
| ARL8B | ADP-ribosylation factor-like 8B |
| GNLY | granulysin |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
| LAMP1 | lysosomal-associated membrane protein 1 |
| NKG7 | natural killer cell granule protein 7 |
| RNF19B | ring finger protein 19B |
| STXBP2 | syntaxin binding protein 2 |
| ZNF395 | zinc finger protein 395 |
