| Dataset | GO Biological Process Annotations 2015 |
| Category | structural or functional annotations |
| Type | biological process |
| Description | Any series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. Cytosolic PRRs such as RIG-I (DDX58) and MDA-5 (IFIH1) detect RNA synthesized during active viral replication and trigger a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. (Gene Ontology, GO_0039528) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0039528 |
| Similar Terms | |
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6 genes participating in the cytoplasmic pattern recognition receptor signaling pathway in response to virus biological process from the curated GO Biological Process Annotations 2015 dataset.
