cytoskeleton Gene Set

Dataset LOCATE Curated Protein Localization Annotations
Category proteomics
Type cellular component
Description Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. (Gene Ontology, GO_0005856)
External Link http://locate.imb.uq.edu.au/searchpages/HumanGO:0005856.shtml
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Genes

183 proteins localized to the cytoskeleton cellular component in low- or high-throughput protein localization assays from the LOCATE Curated Protein Localization Annotations dataset.

Symbol Name
AAK1 AP2 associated kinase 1
ABLIM1 actin binding LIM protein 1
ABRA actin binding Rho activating protein
ACTL7B actin-like 7B
ACTL9 actin-like 9
ACTN1 actinin, alpha 1
ACTR10 actin-related protein 10 homolog (S. cerevisiae)
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ACTR6 ARP6 actin-related protein 6 homolog (yeast)
ACTRT2 actin-related protein T2
AIF1L allograft inflammatory factor 1-like
AIM1 absent in melanoma 1
AKAP12 A kinase (PRKA) anchor protein 12
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARC activity-regulated cytoskeleton-associated protein
ARHGAP24 Rho GTPase activating protein 24
ARHGAP8 Rho GTPase activating protein 8
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARL8B ADP-ribosylation factor-like 8B
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
BFSP1 beaded filament structural protein 1, filensin
BFSP2 beaded filament structural protein 2, phakinin
BICD2 bicaudal D homolog 2 (Drosophila)
BIRC5 baculoviral IAP repeat containing 5
C19ORF47 chromosome 19 open reading frame 47
CABP1 calcium binding protein 1
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2
CAPZA3 capping protein (actin filament) muscle Z-line, alpha 3
CAPZB capping protein (actin filament) muscle Z-line, beta
CCDC6 coiled-coil domain containing 6
CCDC88A coiled-coil domain containing 88A
CCIN calicin
CCNA1 cyclin A1
CCNB2 cyclin B2
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDC42SE1 CDC42 small effector 1
CLIP1 CAP-GLY domain containing linker protein 1
CSNK1A1 casein kinase 1, alpha 1
CSNK1D casein kinase 1, delta
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CTTN cortactin
CTTNBP2NL CTTNBP2 N-terminal like
DBN1 drebrin 1
DGKA diacylglycerol kinase, alpha 80kDa
DNM1 dynamin 1
DNM2 dynamin 2
DSG2 desmoglein 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EIF6 eukaryotic translation initiation factor 6
ENAH enabled homolog (Drosophila)
ENKD1 enkurin domain containing 1
EPB41 erythrocyte membrane protein band 4.1
EPB41L1 erythrocyte membrane protein band 4.1-like 1
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGD4 FYVE, RhoGEF and PH domain containing 4
FHDC1 FH2 domain containing 1
FHL2 four and a half LIM domains 2
FILIP1 filamin A interacting protein 1
FLII flightless I homolog (Drosophila)
FLNA filamin A, alpha
FRMD5 FERM domain containing 5
FRMPD2 FERM and PDZ domain containing 2
GABARAP GABA(A) receptor-associated protein
GAS2L1 growth arrest-specific 2 like 1
GPHN gephyrin
HAUS1 HAUS augmin-like complex, subunit 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGSF1 immunoglobulin superfamily, member 1
KALRN kalirin, RhoGEF kinase
KEAP1 kelch-like ECH-associated protein 1
KIF17 kinesin family member 17
KIF18A kinesin family member 18A
KIF23 kinesin family member 23
KIF24 kinesin family member 24
KIF2C kinesin family member 2C
KLHL17 kelch-like family member 17
KLHL18 kelch-like family member 18
KLHL20 kelch-like family member 20
KLHL41 kelch-like family member 41
KRT72 keratin 72, type II
KRTAP4-1 keratin associated protein 4-1
KRTAP4-5 keratin associated protein 4-5
KRTAP5-4 keratin associated protein 5-4
LIMA1 LIM domain and actin binding 1
LIMCH1 LIM and calponin homology domains 1
LMOD3 leiomodin 3 (fetal)
LYST lysosomal trafficking regulator
MAP2 microtubule-associated protein 2
MAP4 microtubule-associated protein 4
MAP6 microtubule-associated protein 6
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MAPT microtubule-associated protein tau
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MAST1 microtubule associated serine/threonine kinase 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MICU2 mitochondrial calcium uptake 2
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MTSS1 metastasis suppressor 1
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYLIP myosin regulatory light chain interacting protein
MYPN myopalladin
NCK2 NCK adaptor protein 2
NEBL nebulette
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NUSAP1 nucleolar and spindle associated protein 1
OSTF1 osteoclast stimulating factor 1
PCM1 pericentriolar material 1
PDE4D phosphodiesterase 4D, cAMP-specific
PDLIM2 PDZ and LIM domain 2 (mystique)
PDLIM5 PDZ and LIM domain 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PLEC plectin
PLEKHN1 pleckstrin homology domain containing, family N member 1
PNPLA10P patatin-like phospholipase domain containing 10 pseudogene
PNPLA8 patatin-like phospholipase domain containing 8
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma
PRC1 protein regulator of cytokinesis 1
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTK2B protein tyrosine kinase 2 beta
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAE1 ribonucleic acid export 1
RAVER1 ribonucleoprotein, PTB-binding 1
RDX radixin
RHOF ras homolog family member F (in filopodia)
ROR1 receptor tyrosine kinase-like orphan receptor 1
ROR2 receptor tyrosine kinase-like orphan receptor 2
SEPT3 septin 3
SEPT4 septin 4
SEPT7 septin 7
SGCZ sarcoglycan, zeta
SH3KBP1 SH3-domain kinase binding protein 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIPA1 signal-induced proliferation-associated 1
SNTG1 syntrophin, gamma 1
SORBS1 sorbin and SH3 domain containing 1
SPAG5 sperm associated antigen 5
SPAG6 sperm associated antigen 6
SPAST spastin
SPATA7 spermatogenesis associated 7
SPATS2L spermatogenesis associated, serine-rich 2-like
SPEF1 sperm flagellar 1
SPIRE1 spire-type actin nucleation factor 1
SPTBN5 spectrin, beta, non-erythrocytic 5
SSH1 slingshot protein phosphatase 1
SSH2 slingshot protein phosphatase 2
STRBP spermatid perinuclear RNA binding protein
SVIL supervillin
SYNE1 spectrin repeat containing, nuclear envelope 1
SYNE3 spectrin repeat containing, nuclear envelope family member 3
SYNPO synaptopodin
SYNPO2 synaptopodin 2
TBCA tubulin folding cofactor A
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TEKT1 tektin 1
TEKT5 tektin 5
TEX35 testis expressed 35
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THAP6 THAP domain containing 6
TPM2 tropomyosin 2 (beta)
TPM4 tropomyosin 4
TPPP tubulin polymerization promoting protein
TPT1 tumor protein, translationally-controlled 1
TPX2 TPX2, microtubule-associated
TRADD TNFRSF1A-associated via death domain
TUBA8 tubulin, alpha 8
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VASP vasodilator-stimulated phosphoprotein
VCL vinculin
VILL villin-like
VIM vimentin
WDR1 WD repeat domain 1
WDR44 WD repeat domain 44
WIPF1 WAS/WASL interacting protein family, member 1
WIPF2 WAS/WASL interacting protein family, member 2
ZSCAN21 zinc finger and SCAN domain containing 21
ZYX zyxin