cytosol Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. (Gene Ontology, GO_0005829)
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Genes

262 genes co-occuring with the biological term cytosol in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACOT8 acyl-CoA thioesterase 8
ACVR1 activin A receptor, type I
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALDOA aldolase A, fructose-bisphosphate
ANXA4 annexin A4
APOA1 apolipoprotein A-I
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARMS2 age-related maculopathy susceptibility 2
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
ATP6V1G3 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
ATP7B ATPase, Cu++ transporting, beta polypeptide
AURKA aurora kinase A
BAAT bile acid CoA:amino acid N-acyltransferase
BAG6 BCL2-associated athanogene 6
BAX BCL2-associated X protein
BCAP31 B-cell receptor-associated protein 31
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BEST1 bestrophin 1
BID BH3 interacting domain death agonist
BIK BCL2-interacting killer (apoptosis-inducing)
BOK BCL2-related ovarian killer
BST2 bone marrow stromal cell antigen 2
CA2 carbonic anhydrase II
CA4 carbonic anhydrase IV
CALHM1 calcium homeostasis modulator 1
CAPN1 calpain 1, (mu/I) large subunit
CAPN2 calpain 2, (m/II) large subunit
CARKD carbohydrate kinase domain containing
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAST calpastatin
CAT catalase
CC2D1A coiled-coil and C2 domain containing 1A
CD209 CD209 molecule
CD4 CD4 molecule
CD99 CD99 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CERK ceramide kinase
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHAT choline O-acetyltransferase
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLU clusterin
COMMD1 copper metabolism (Murr1) domain containing 1
COMT catechol-O-methyltransferase
CREB1 cAMP responsive element binding protein 1
CTNND1 catenin (cadherin-associated protein), delta 1
CTNND2 catenin (cadherin-associated protein), delta 2
CTSB cathepsin B
CTSD cathepsin D
CTSL cathepsin L
CXCL8 chemokine (C-X-C motif) ligand 8
DAXX death-domain associated protein
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DERL1 derlin 1
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DIABLO diablo, IAP-binding mitochondrial protein
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNM1L dynamin 1-like
DPP9 dipeptidyl-peptidase 9
DSG2 desmoglein 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EGF epidermal growth factor
ELANE elastase, neutrophil expressed
ENG endoglin
ENGASE endo-beta-N-acetylglucosaminidase
EPHB2 EPH receptor B2
ERAP1 endoplasmic reticulum aminopeptidase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FASN fatty acid synthase
FBXW11 F-box and WD repeat domain containing 11
FHIT fragile histidine triad
FOXO3 forkhead box O3
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GCHFR GTP cyclohydrolase I feedback regulator
GFER growth factor, augmenter of liver regeneration
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNLY granulysin
GOLGA4 golgin A4
GRB2 growth factor receptor-bound protein 2
GSK3B glycogen synthase kinase 3 beta
GSTA1 glutathione S-transferase alpha 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HID1 HID1 domain containing
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-G major histocompatibility complex, class I, G
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HTN3 histatin 3
HTRA1 HtrA serine peptidase 1
HTRA2 HtrA serine peptidase 2
HTT huntingtin
ICMT isoprenylcysteine carboxyl methyltransferase
IDE insulin-degrading enzyme
IFNB1 interferon, beta 1, fibroblast
IL6 interleukin 6
INS insulin
INSIG1 insulin induced gene 1
IRAK1 interleukin-1 receptor-associated kinase 1
JUP junction plakoglobin
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIF2A kinesin heavy chain member 2A
LCK LCK proto-oncogene, Src family tyrosine kinase
LGALS8 lectin, galactoside-binding, soluble, 8
LYPLA1 lysophospholipase I
MAD2L1BP MAD2L1 binding protein
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
MARK2 MAP/microtubule affinity-regulating kinase 2
MAVS mitochondrial antiviral signaling protein
MCL1 myeloid cell leukemia 1
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MKNK1 MAP kinase interacting serine/threonine kinase 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MLXIPL MLX interacting protein-like
MMP3 matrix metallopeptidase 3
MOCS3 molybdenum cofactor synthesis 3
MSH3 mutS homolog 3
MSRA methionine sulfoxide reductase A
MSRB2 methionine sulfoxide reductase B2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NADK2 NAD kinase 2, mitochondrial
NCOA4 nuclear receptor coactivator 4
NEU1 sialidase 1 (lysosomal sialidase)
NEU3 sialidase 3 (membrane sialidase)
NF1 neurofibromin 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFS1 NFS1 cysteine desulfurase
NGLY1 N-glycanase 1
NMNAT1 nicotinamide nucleotide adenylyltransferase 1
NMT1 N-myristoyltransferase 1
NOS3 nitric oxide synthase 3 (endothelial cell)
NPC1 Niemann-Pick disease, type C1
NPC1L1 NPC1-like 1
NR2C2 nuclear receptor subfamily 2, group C, member 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OTC ornithine carbamoyltransferase
PARK2 parkin RBR E3 ubiquitin protein ligase
PDCD6IP programmed cell death 6 interacting protein
PDE5A phosphodiesterase 5A, cGMP-specific
PDIA3 protein disulfide isomerase family A, member 3
PDPK1 3-phosphoinositide dependent protein kinase 1
PEX11G peroxisomal biogenesis factor 11 gamma
PEX19 peroxisomal biogenesis factor 19
PEX26 peroxisomal biogenesis factor 26
PEX5 peroxisomal biogenesis factor 5
PEX7 peroxisomal biogenesis factor 7
PGAM5 phosphoglycerate mutase family member 5
PHB prohibitin
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PINK1 PTEN induced putative kinase 1
PKP3 plakophilin 3
PLAU plasminogen activator, urokinase
PLCB2 phospholipase C, beta 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLK1 polo-like kinase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPARG peroxisome proliferator-activated receptor gamma
PRDX2 peroxiredoxin 2
PRDX4 peroxiredoxin 4
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRNP prion protein
PRUNE2 prune homolog 2 (Drosophila)
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTPRE protein tyrosine phosphatase, receptor type, E
PTRH2 peptidyl-tRNA hydrolase 2
RAB27A RAB27A, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RHOA ras homolog family member A
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RNH1 ribonuclease/angiogenin inhibitor 1
RPS3 ribosomal protein S3
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPTOR regulatory associated protein of MTOR, complex 1
RYR2 ryanodine receptor 2 (cardiac)
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFN stratifin
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIRT1 sirtuin 1
SIRT3 sirtuin 3
SIVA1 SIVA1, apoptosis-inducing factor
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOS2 son of sevenless homolog 2 (Drosophila)
SOX4 SRY (sex determining region Y)-box 4
SPPL2B signal peptide peptidase like 2B
SRI sorcin
SRSF1 serine/arginine-rich splicing factor 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TIAM1 T-cell lymphoma invasion and metastasis 1
TMEM173 transmembrane protein 173
TNF tumor necrosis factor
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TOLLIP toll interacting protein
TOMM34 translocase of outer mitochondrial membrane 34
TP53 tumor protein p53
TP63 tumor protein p63
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM22 tripartite motif containing 22
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TTR transthyretin
TXNDC16 thioredoxin domain containing 16
TYMP thymidine phosphorylase
UBQLN1 ubiquilin 1
UBXN1 UBX domain protein 1
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
USP9X ubiquitin specific peptidase 9, X-linked
UVRAG UV radiation resistance associated
VCP valosin containing protein
VDAC2 voltage-dependent anion channel 2
VEGFA vascular endothelial growth factor A
XPO1 exportin 1
ZNF268 zinc finger protein 268