cytotoxic Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

116 proteins co-occuring with the biological term cytotoxic in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
APP amyloid beta (A4) precursor protein
ATM ATM serine/threonine kinase
AURKA aurora kinase A
AURKB aurora kinase B
BAD BCL2-associated agonist of cell death
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCR breakpoint cluster region
BIRC5 baculoviral IAP repeat containing 5
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CD84 CD84 molecule
CDC25C cell division cycle 25C
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHD4 chromodomain helicase DNA binding protein 4
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CREB1 cAMP responsive element binding protein 1
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DCK deoxycytidine kinase
EGFR epidermal growth factor receptor
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELK1 ELK1, member of ETS oncogene family
F3 coagulation factor III (thromboplastin, tissue factor)
FAS Fas cell surface death receptor
FCRL6 Fc receptor-like 6
FOXO1 forkhead box O1
FRK fyn-related Src family tyrosine kinase
GJA1 gap junction protein, alpha 1, 43kDa
GLO1 glyoxalase I
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GYS1 glycogen synthase 1 (muscle)
H2AFX H2A histone family, member X
H3F3A H3 histone, family 3A
HDAC6 histone deacetylase 6
HIST1H3A histone cluster 1, H3a
HSF1 heat shock transcription factor 1
HTT huntingtin
IFNAR1 interferon (alpha, beta and omega) receptor 1
JUN jun proto-oncogene
KAT7 K(lysine) acetyltransferase 7
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KLRF1 killer cell lectin-like receptor subfamily F, member 1
KRT8 keratin 8, type II
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LRRK2 leucine-rich repeat kinase 2
MAF1 MAF1 homolog (S. cerevisiae)
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIP major intrinsic protein of lens fiber
MKNK1 MAP kinase interacting serine/threonine kinase 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH9 myosin, heavy chain 9, non-muscle
NBN nibrin
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKCD protein kinase C, delta
PRKCG protein kinase C, gamma
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PTEN phosphatase and tensin homolog
PTK2B protein tyrosine kinase 2 beta
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RPA2 replication protein A2, 32kDa
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SMC1A structural maintenance of chromosomes 1A
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STMN1 stathmin 1
SYK spleen tyrosine kinase
TACC3 transforming, acidic coiled-coil containing protein 3
TIGIT T cell immunoreceptor with Ig and ITIM domains
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TRIM28 tripartite motif containing 28
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC2 tuberous sclerosis 2
VAV1 vav 1 guanine nucleotide exchange factor
VCP valosin containing protein
WWOX WW domain containing oxidoreductase
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa