d-2-hydroxyglutaric aciduria Gene Set

Dataset	DISEASES Text-mining Gene-Disease Association Evidence Scores
Category	disease or phenotype associations
Type	disease
Description	An 2-hydroxyglutaric aciduria that involves developmental delay, seizures, weak muscle tone (hypotonia), and abnormalities in the largest part of the brain (the cerebrum), which controls many important functions such as muscle movement, speech, vision, thinking, emotion, and memory. (Human Disease Ontology, DOID_0050575)
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Genes

15 genes co-occuring with the disease d-2-hydroxyglutaric aciduria in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol	Name	Standardized Value
D2HGDH	D-2-hydroxyglutarate dehydrogenase	2.84171
IDH1	isocitrate dehydrogenase 1 (NADP+), soluble	1.48428
IDH2	isocitrate dehydrogenase 2 (NADP+), mitochondrial	1.47682
ATP5O	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit	1.12151
GLS2	glutaminase 2 (liver, mitochondrial)	0.847898
ALDH5A1	aldehyde dehydrogenase 5 family, member A1	0.847488
GCDH	glutaryl-CoA dehydrogenase	0.80977
PHGDH	phosphoglycerate dehydrogenase	0.793771
GSS	glutathione synthetase	0.726929
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.616312
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.499231
GPX5	glutathione peroxidase 5	0.411283
GPX4	glutathione peroxidase 4	0.407919
GPX1	glutathione peroxidase 1	0.393001
SOD2	superoxide dismutase 2, mitochondrial	0.212945