dabigatran Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amoino group of N-pyridin-2-yl-beta-alanine. The active metabolite of the prodrug dabigatran etexilate, it acts as an anticoagulant which is used for the prevention of stroke and systemic embolism. (Chemical Entities of Biological Interest Ontology, CHEBI_70752)
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Genes

6 genes co-occuring with the biological term dabigatran in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
CES1 carboxylesterase 1
CES2 carboxylesterase 2
CPB2 carboxypeptidase B2 (plasma)
F2 coagulation factor II (thrombin)
PROC protein C (inactivator of coagulation factors Va and VIIIa)