| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the dacarbazine-1762 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| ASPH | aspartate beta-hydroxylase |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C21ORF33 | chromosome 21 open reading frame 33 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CAPN10 | calpain 10 |
| CBX6 | chromobox homolog 6 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CPNE1 | copine I |
| CPT2 | carnitine palmitoyltransferase 2 |
| DBF4 | DBF4 zinc finger |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DUS2 | dihydrouridine synthase 2 |
| DXO | decapping exoribonuclease |
| ELK1 | ELK1, member of ETS oncogene family |
| ELMO2 | engulfment and cell motility 2 |
| ERCC8 | excision repair cross-complementation group 8 |
| ESRRA | estrogen-related receptor alpha |
| FANCA | Fanconi anemia, complementation group A |
| FBLN1 | fibulin 1 |
| FMOD | fibromodulin |
| GCDH | glutaryl-CoA dehydrogenase |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) |
| GPSM3 | G-protein signaling modulator 3 |
| HDAC5 | histone deacetylase 5 |
| HP | haptoglobin |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| IFFO1 | intermediate filament family orphan 1 |
| IFITM3 | interferon induced transmembrane protein 3 |
| ING4 | inhibitor of growth family, member 4 |
| KIAA1109 | KIAA1109 |
| KLHL21 | kelch-like family member 21 |
| LAT2 | linker for activation of T cells family, member 2 |
| LMTK1 | lemur tail kinase 1 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LSM12 | LSM12 homolog (S. cerevisiae) |
| MAGED2 | melanoma antigen family D2 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MKL2 | MKL/myocardin-like 2 |
| MLYCD | malonyl-CoA decarboxylase |
| MPV17 | MpV17 mitochondrial inner membrane protein |
| MPZL1 | myelin protein zero-like 1 |
| MSRB1 | methionine sulfoxide reductase B1 |
| MT3 | metallothionein 3 |
| MYT1 | myelin transcription factor 1 |
| N4BP1 | NEDD4 binding protein 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NEFH | neurofilament, heavy polypeptide |
| NELFE | negative elongation factor complex member E |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| ORC4 | origin recognition complex, subunit 4 |
| OSBPL1A | oxysterol binding protein-like 1A |
| PADI4 | peptidyl arginine deiminase, type IV |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PDCD11 | programmed cell death 11 |
| PEPD | peptidase D |
| PLEK2 | pleckstrin 2 |
| PRDM4 | PR domain containing 4 |
| PRKCA | protein kinase C, alpha |
| PTGES | prostaglandin E synthase |
| RABIF | RAB interacting factor |
| RHOT2 | ras homolog family member T2 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPL18 | ribosomal protein L18 |
| RUNX1 | runt-related transcription factor 1 |
| S100A12 | S100 calcium binding protein A12 |
| S100A9 | S100 calcium binding protein A9 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SETDB1 | SET domain, bifurcated 1 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) |
| SPN | sialophorin |
| SRCAP | Snf2-related CREBBP activator protein |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| TAOK2 | TAO kinase 2 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMED1 | transmembrane emp24 protein transport domain containing 1 |
| TRMT61A | tRNA methyltransferase 61A |
| UBE3A | ubiquitin protein ligase E3A |
| WSB2 | WD repeat and SOCS box containing 2 |
| Symbol | Name |
|---|---|
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase |
| ABT1 | activator of basal transcription 1 |
| ACOT8 | acyl-CoA thioesterase 8 |
| ALPK1 | alpha-kinase 1 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATXN2 | ataxin 2 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BCOR | BCL6 corepressor |
| BTBD1 | BTB (POZ) domain containing 1 |
| BTNL3 | butyrophilin-like 3 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CCDC47 | coiled-coil domain containing 47 |
| CD69 | CD69 molecule |
| CD9 | CD9 molecule |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLK1 | CDC-like kinase 1 |
| COMMD10 | COMM domain containing 10 |
| CRY1 | cryptochrome circadian clock 1 |
| DAZAP1 | DAZ associated protein 1 |
| DIXDC1 | DIX domain containing 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| DPYD | dihydropyrimidine dehydrogenase |
| DSN1 | DSN1, MIS12 kinetochore complex component |
| ECT2 | epithelial cell transforming 2 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| EMC2 | ER membrane protein complex subunit 2 |
| EXOC5 | exocyst complex component 5 |
| FAM222B | family with sequence similarity 222, member B |
| FAM63A | family with sequence similarity 63, member A |
| FGF4 | fibroblast growth factor 4 |
| FLCN | folliculin |
| FOXJ2 | forkhead box J2 |
| FRAT1 | frequently rearranged in advanced T-cell lymphomas 1 |
| FUBP3 | far upstream element (FUSE) binding protein 3 |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GDI1 | GDP dissociation inhibitor 1 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 |
| GPR27 | G protein-coupled receptor 27 |
| HAL | histidine ammonia-lyase |
| HIRA | histone cell cycle regulator |
| HK1 | hexokinase 1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IRF7 | interferon regulatory factor 7 |
| ITGAV | integrin, alpha V |
| KIAA0894 | KIAA0894 protein |
| KIF3B | kinesin family member 3B |
| KIFAP3 | kinesin-associated protein 3 |
| KIFC1 | kinesin family member C1 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MCRS1 | microspherule protein 1 |
| MED17 | mediator complex subunit 17 |
| MICB | MHC class I polypeptide-related sequence B |
| MON1B | MON1 secretory trafficking family member B |
| MRPL42 | mitochondrial ribosomal protein L42 |
| MRPS15 | mitochondrial ribosomal protein S15 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NMD3 | NMD3 ribosome export adaptor |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCTP | phosphatidylcholine transfer protein |
| PEX26 | peroxisomal biogenesis factor 26 |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PRPF39 | pre-mRNA processing factor 39 |
| RAB17 | RAB17, member RAS oncogene family |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RASA2 | RAS p21 protein activator 2 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RSF1 | remodeling and spacing factor 1 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SERPINB10 | serpin peptidase inhibitor, clade B (ovalbumin), member 10 |
| SFXN1 | sideroflexin 1 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa |
| SPIN1 | spindlin 1 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 |
| TMEM45A | transmembrane protein 45A |
| TMEM53 | transmembrane protein 53 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| XPC | xeroderma pigmentosum, complementation group C |
| ZNF143 | zinc finger protein 143 |
| ZNF175 | zinc finger protein 175 |
| ZNF562 | zinc finger protein 562 |
| ZNF721 | zinc finger protein 721 |