| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the dacarbazine-2754 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABO | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) |
| ADAM5 | ADAM metallopeptidase domain 5 (pseudogene) |
| AGXT | alanine-glyoxylate aminotransferase |
| AIF1 | allograft inflammatory factor 1 |
| AIM2 | absent in melanoma 2 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 |
| C11ORF1 | chromosome 11 open reading frame 1 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DBP | D site of albumin promoter (albumin D-box) binding protein |
| DOK4 | docking protein 4 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EHD1 | EH-domain containing 1 |
| EHD2 | EH-domain containing 2 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| EPHA5 | EPH receptor A5 |
| ETV5 | ets variant 5 |
| EXOSC2 | exosome component 2 |
| FBXO41 | F-box protein 41 |
| FLJ22184 | |
| FRMD4A | FERM domain containing 4A |
| GLIPR1 | GLI pathogenesis-related 1 |
| GLRA3 | glycine receptor, alpha 3 |
| GPR15 | G protein-coupled receptor 15 |
| GRB10 | growth factor receptor-bound protein 10 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXB2 | homeobox B2 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HYAL1 | hyaluronoglucosaminidase 1 |
| IL2RB | interleukin 2 receptor, beta |
| IL6R | interleukin 6 receptor |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
| KAZN | kazrin, periplakin interacting protein |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| LHX2 | LIM homeobox 2 |
| LTC4S | leukotriene C4 synthase |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K |
| MAP4 | microtubule-associated protein 4 |
| MAU2 | MAU2 sister chromatid cohesion factor |
| MST1 | macrophage stimulating 1 |
| MTA2 | metastasis associated 1 family, member 2 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NDRG2 | NDRG family member 2 |
| NOV | nephroblastoma overexpressed |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PHF14 | PHD finger protein 14 |
| PHOX2B | paired-like homeobox 2b |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLLP | plasmolipin |
| PLXNC1 | plexin C1 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme |
| PSG1 | pregnancy specific beta-1-glycoprotein 1 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| PTRF | polymerase I and transcript release factor |
| RAB6B | RAB6B, member RAS oncogene family |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RNF122 | ring finger protein 122 |
| RNF216 | ring finger protein 216 |
| RNF39 | ring finger protein 39 |
| RPL35A | ribosomal protein L35a |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SH2D3A | SH2 domain containing 3A |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SLN | sarcolipin |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TMEM176A | transmembrane protein 176A |
| TMOD2 | tropomodulin 2 (neuronal) |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| VIM | vimentin |
| VN1R1 | vomeronasal 1 receptor 1 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF175 | zinc finger protein 175 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADCY6 | adenylate cyclase 6 |
| ALS2CL | ALS2 C-terminal like |
| APH1B | APH1B gamma secretase subunit |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARMC6 | armadillo repeat containing 6 |
| ARSB | arylsulfatase B |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCORL1 | BCL6 corepressor-like 1 |
| BMP4 | bone morphogenetic protein 4 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C5AR2 | complement component 5a receptor 2 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC85C | coiled-coil domain containing 85C |
| CDK3 | cyclin-dependent kinase 3 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHKB | choline kinase beta |
| CISH | cytokine inducible SH2-containing protein |
| COL9A2 | collagen, type IX, alpha 2 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DSCAM | Down syndrome cell adhesion molecule |
| ENO2 | enolase 2 (gamma, neuronal) |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FAM63A | family with sequence similarity 63, member A |
| FBXO46 | F-box protein 46 |
| FLCN | folliculin |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| INCENP | inner centromere protein antigens 135/155kDa |
| ITPKB | inositol-trisphosphate 3-kinase B |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LMNB1 | lamin B1 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| MBTD1 | mbt domain containing 1 |
| MEX3C | mex-3 RNA binding family member C |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs |
| MMP9 | matrix metallopeptidase 9 |
| MTCP1 | mature T-cell proliferation 1 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MXD3 | MAX dimerization protein 3 |
| NDRG1 | N-myc downstream regulated 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOL12 | nucleolar protein 12 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 |
| PARPBP | PARP1 binding protein |
| PC | pyruvate carboxylase |
| PCDHA6 | protocadherin alpha 6 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLA2G10 | phospholipase A2, group X |
| PLA2G15 | phospholipase A2, group XV |
| PODXL | podocalyxin-like |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit |
| RNF170 | ring finger protein 170 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SETD1A | SET domain containing 1A |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC35F5 | solute carrier family 35, member F5 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPIDR | scaffolding protein involved in DNA repair |
| TCP10 | t-complex 10 |
| TMCO3 | transmembrane and coiled-coil domains 3 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRAPPC2 | trafficking protein particle complex 2 |
| TSPAN5 | tetraspanin 5 |
| TUBA3D | tubulin, alpha 3d |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZDHHC24 | zinc finger, DHHC-type containing 24 |
| ZNF205 | zinc finger protein 205 |
| ZNF212 | zinc finger protein 212 |
| ZNF350 | zinc finger protein 350 |
