| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the dacarbazine-6816 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ADGRB3 | adhesion G protein-coupled receptor B3 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| AMT | aminomethyltransferase |
| ANGPTL2 | angiopoietin-like 2 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATG10 | autophagy related 10 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
| CARD10 | caspase recruitment domain family, member 10 |
| CARD14 | caspase recruitment domain family, member 14 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCL16 | chemokine (C-C motif) ligand 16 |
| CDK18 | cyclin-dependent kinase 18 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CPNE7 | copine VII |
| CPQ | carboxypeptidase Q |
| CYB5R2 | cytochrome b5 reductase 2 |
| DAGLA | diacylglycerol lipase, alpha |
| DCN | decorin |
| DOCK6 | dedicator of cytokinesis 6 |
| DPYS | dihydropyrimidinase |
| DSC3 | desmocollin 3 |
| EDAR | ectodysplasin A receptor |
| EHD2 | EH-domain containing 2 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ERCC2 | excision repair cross-complementation group 2 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FGF13 | fibroblast growth factor 13 |
| FLJ11292 | |
| FN1 | fibronectin 1 |
| FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GPR137 | G protein-coupled receptor 137 |
| GRM1 | glutamate receptor, metabotropic 1 |
| HAP1 | huntingtin-associated protein 1 |
| HEMK1 | HemK methyltransferase family member 1 |
| HESX1 | HESX homeobox 1 |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IL1RAP | interleukin 1 receptor accessory protein |
| IL1RN | interleukin 1 receptor antagonist |
| INO80B | INO80 complex subunit B |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| KAT6A | K(lysine) acetyltransferase 6A |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KHSRP | KH-type splicing regulatory protein |
| KIAA1109 | KIAA1109 |
| KIAA1462 | KIAA1462 |
| KIF25-AS1 | KIF25 antisense RNA 1 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MST1R | macrophage stimulating 1 receptor |
| MUC8 | mucin 8 |
| MYBPC3 | myosin binding protein C, cardiac |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NAAA | N-acylethanolamine acid amidase |
| NAG18 | NAG18 mRNA |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| ONECUT2 | one cut homeobox 2 |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PER1 | period circadian clock 1 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PIP | prolactin-induced protein |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PRKCE | protein kinase C, epsilon |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PVR | poliovirus receptor |
| PXDC1 | PX domain containing 1 |
| RABGAP1L | RAB GTPase activating protein 1-like |
| REEP2 | receptor accessory protein 2 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF208 | ring finger protein 208 |
| RUNDC3A | RUN domain containing 3A |
| SCLY | selenocysteine lyase |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SIK3 | SIK family kinase 3 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SIX3 | SIX homeobox 3 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRR1A | small proline-rich protein 1A |
| SPRR2B | small proline-rich protein 2B |
| TAT | tyrosine aminotransferase |
| TBKBP1 | TBK1 binding protein 1 |
| TBL2 | transducin (beta)-like 2 |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TFF2 | trefoil factor 2 |
| TGFB1 | transforming growth factor, beta 1 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TUBA4B | tubulin, alpha 4b |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ALS2CL | ALS2 C-terminal like |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BAG4 | BCL2-associated athanogene 4 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CAPG | capping protein (actin filament), gelsolin-like |
| CBX8 | chromobox homolog 8 |
| CCNO | cyclin O |
| CD302 | CD302 molecule |
| CD82 | CD82 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CRY2 | cryptochrome circadian clock 2 |
| CTBS | chitobiase, di-N-acetyl- |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOC2A | double C2-like domains, alpha |
| DUSP2 | dual specificity phosphatase 2 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EDC4 | enhancer of mRNA decapping 4 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| F2R | coagulation factor II (thrombin) receptor |
| F8 | coagulation factor VIII, procoagulant component |
| FAM204A | family with sequence similarity 204, member A |
| FAM63A | family with sequence similarity 63, member A |
| FBXW12 | F-box and WD repeat domain containing 12 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GPATCH3 | G patch domain containing 3 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXC8 | homeobox C8 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL4R | interleukin 4 receptor |
| IMPACT | impact RWD domain protein |
| KAT2A | K(lysine) acetyltransferase 2A |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| MAP9 | microtubule-associated protein 9 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MVP | major vault protein |
| MYO1D | myosin ID |
| NDRG1 | N-myc downstream regulated 1 |
| NEK11 | NIMA-related kinase 11 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NRSN2 | neurensin 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PADI3 | peptidyl arginine deiminase, type III |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RUFY2 | RUN and FYVE domain containing 2 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SYNGR3 | synaptogyrin 3 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TH | tyrosine hydroxylase |
| THBS3 | thrombospondin 3 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TRABD | TraB domain containing |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TUBA3C | tubulin, alpha 3c |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| UNC119 | unc-119 homolog (C. elegans) |
| VASH1 | vasohibin 1 |
| WDR4 | WD repeat domain 4 |
| WLS | wntless Wnt ligand secretion mediator |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF219 | zinc finger protein 219 |
| ZNF268 | zinc finger protein 268 |
| ZNF282 | zinc finger protein 282 |
| ZNF324 | zinc finger protein 324 |
| ZNF516 | zinc finger protein 516 |
| ZNF571 | zinc finger protein 571 |
| ZNF675 | zinc finger protein 675 |