dactinomycin Gene Set
Genes
19 genes differentially expressed following the dactinomycin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
decreased expression
| Symbol |
Name |
Standardized Value |
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
-4.59627
|
|
TBP
|
TATA box binding protein
|
-4.42589
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-4.2571
|
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
-4.13707
|
|
NGDN
|
neuroguidin, EIF4E binding protein
|
-3.74635
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
-3.56034
|
|
JMJD6
|
jumonji domain containing 6
|
-3.4204
|
|
SLC6A2
|
solute carrier family 6 (neurotransmitter transporter), member 2
|
-3.39864
|
|
CDC25A
|
cell division cycle 25A
|
-3.37336
|
|
TTC4
|
tetratricopeptide repeat domain 4
|
-3.36155
|
|
BRPF1
|
bromodomain and PHD finger containing, 1
|
-3.28399
|
|
EIF4ENIF1
|
eukaryotic translation initiation factor 4E nuclear import factor 1
|
-3.26735
|
|
MRM3
|
mitochondrial rRNA methyltransferase 3
|
-3.24323
|
|
ZNF202
|
zinc finger protein 202
|
-3.19229
|
|
TMEM11
|
transmembrane protein 11
|
-3.12066
|
|
CHERP
|
calcium homeostasis endoplasmic reticulum protein
|
-3.10999
|
|
GEMIN4
|
gem (nuclear organelle) associated protein 4
|
-3.0825
|
|
BAG5
|
BCL2-associated athanogene 5
|
-3.07439
|
|
CSTF1
|
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
|
-3.06717
|
