damaged Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

178 genes co-occuring with the biological term damaged in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
AGER advanced glycosylation end product-specific receptor
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOA1 apolipoprotein A-I
APTX aprataxin
ATF3 activating transcription factor 3
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BLM Bloom syndrome, RecQ helicase-like
BMP2 bone morphogenetic protein 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C10ORF2 chromosome 10 open reading frame 2
C19ORF40 chromosome 19 open reading frame 40
C3 complement component 3
C9ORF142 chromosome 9 open reading frame 142
CBX5 chromobox homolog 5
CD34 CD34 molecule
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDT1 chromatin licensing and DNA replication factor 1
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CETN2 centrin, EF-hand protein, 2
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHEK1 checkpoint kinase 1
CHIT1 chitinase 1 (chitotriosidase)
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
CKBE creatine kinase, ectopic expression
CLDN4 claudin 4
CRP C-reactive protein, pentraxin-related
CRYGD crystallin, gamma D
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL4A cullin 4A
CXADR coxsackie virus and adenovirus receptor
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
DAZ1 deleted in azoospermia 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
DMBT1 deleted in malignant brain tumors 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
E2F1 E2F transcription factor 1
E2F7 E2F transcription factor 7
ELANE elastase, neutrophil expressed
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
FANCC Fanconi anemia, complementation group C
FANCD2 Fanconi anemia, complementation group D2
FANCI Fanconi anemia, complementation group I
FGF2 fibroblast growth factor 2 (basic)
FGF7 fibroblast growth factor 7
FKBP1A FK506 binding protein 1A, 12kDa
FOXA2 forkhead box A2
FUNDC1 FUN14 domain containing 1
GLI1 GLI family zinc finger 1
GLI2 GLI family zinc finger 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HAVCR1 hepatitis A virus cellular receptor 1
HDAC1 histone deacetylase 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLTF helicase-like transcription factor
HMOX1 heme oxygenase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPA4 heat shock 70kDa protein 4
HSPA7 heat shock 70kDa protein 7 (HSP70B)
HUS1 HUS1 checkpoint homolog (S. pombe)
IFNG interferon, gamma
IGF1R insulin-like growth factor 1 receptor
IL18 interleukin 18
IL6 interleukin 6
ILK integrin-linked kinase
IRF1 interferon regulatory factor 1
IRS1 insulin receptor substrate 1
LAMA3 laminin, alpha 3
LIF leukemia inhibitory factor
LRRK2 leucine-rich repeat kinase 2
MBP myelin basic protein
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MFN1 mitofusin 1
MFN2 mitofusin 2
MGMT O-6-methylguanine-DNA methyltransferase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MLH1 mutL homolog 1
MPG N-methylpurine-DNA glycosylase
MPO myeloperoxidase
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MUTYH mutY homolog
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NBN nibrin
NCAM1 neural cell adhesion molecule 1
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NHEJ1 nonhomologous end-joining factor 1
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX1 NADPH oxidase 1
NRG1 neuregulin 1
OGG1 8-oxoguanine DNA glycosylase
PARG poly (ADP-ribose) glycohydrolase
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PCNA proliferating cell nuclear antigen
PINK1 PTEN induced putative kinase 1
PNKP polynucleotide kinase 3'-phosphatase
POLH polymerase (DNA directed), eta
POLK polymerase (DNA directed) kappa
POLL polymerase (DNA directed), lambda
PRELP proline/arginine-rich end leucine-rich repeat protein
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PTN pleiotrophin
PTX3 pentraxin 3, long
RAD1 RAD1 checkpoint DNA exonuclease
RAD51 RAD51 recombinase
RAD51D RAD51 paralog D
RAD9A RAD9 homolog A (S. pombe)
RECQL4 RecQ protein-like 4
REG1A regenerating islet-derived 1 alpha
REV1 REV1, polymerase (DNA directed)
RFC1 replication factor C (activator 1) 1, 145kDa
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RPA1 replication protein A1, 70kDa
RPS3 ribosomal protein S3
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RSF1 remodeling and spacing factor 1
S100A4 S100 calcium binding protein A4
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
S1PR1 sphingosine-1-phosphate receptor 1
S1PR2 sphingosine-1-phosphate receptor 2
S1PR3 sphingosine-1-phosphate receptor 3
SCARB1 scavenger receptor class B, member 1
SELL selectin L
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SHH sonic hedgehog
SLPI secretory leukocyte peptidase inhibitor
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SORBS2 sorbin and SH3 domain containing 2
SPP1 secreted phosphoprotein 1
SPRTN SprT-like N-terminal domain
SQSTM1 sequestosome 1
STAT1 signal transducer and activator of transcription 1, 91kDa
TDG thymine-DNA glycosylase
TERT telomerase reverse transcriptase
TFF2 trefoil factor 2
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
TOP1 topoisomerase (DNA) I
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP53I3 tumor protein p53 inducible protein 3
TP63 tumor protein p63
TRPC3 transient receptor potential cation channel, subfamily C, member 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ULK1 unc-51 like autophagy activating kinase 1
UNG uracil-DNA glycosylase
VCP valosin containing protein
VEGFA vascular endothelial growth factor A
VIM vimentin
VSX1 visual system homeobox 1
WRN Werner syndrome, RecQ helicase-like
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YBX1 Y box binding protein 1
YBX3 Y box binding protein 3
ZMYND8 zinc finger, MYND-type containing 8