danazol-2038 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the danazol-2038 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRB2 adhesion G protein-coupled receptor B2
ADK adenosine kinase
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AIM1L absent in melanoma 1-like
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B9D1 B9 protein domain 1
BIRC7 baculoviral IAP repeat containing 7
BMP2K BMP2 inducible kinase
C2ORF54 chromosome 2 open reading frame 54
CA12 carbonic anhydrase XII
CACFD1 calcium channel flower domain containing 1
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CALB2 calbindin 2
CC2D1A coiled-coil and C2 domain containing 1A
CD82 CD82 molecule
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CNTFR ciliary neurotrophic factor receptor
COMT catechol-O-methyltransferase
CORT cortistatin
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLX2 distal-less homeobox 2
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DOC2B double C2-like domains, beta
DRD5 dopamine receptor D5
DUSP26 dual specificity phosphatase 26 (putative)
EIF1 eukaryotic translation initiation factor 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FSCN1 fascin actin-bundling protein 1
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GIPC1 GIPC PDZ domain containing family, member 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNL1 guanine nucleotide binding protein-like 1
GPX3 glutathione peroxidase 3
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HAMP hepcidin antimicrobial peptide
HAND1 heart and neural crest derivatives expressed 1
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IGHA1 immunoglobulin heavy constant alpha 1
IL9R interleukin 9 receptor
IQCK IQ motif containing K
KIF25 kinesin family member 25
KIF25-AS1 KIF25 antisense RNA 1
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAX1 lymphocyte transmembrane adaptor 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMS2 LIM and senescent cell antigen-like domains 2
MAP1A microtubule-associated protein 1A
MED27 mediator complex subunit 27
MFSD11 major facilitator superfamily domain containing 11
MIIP migration and invasion inhibitory protein
MMP7 matrix metallopeptidase 7
MRC2 mannose receptor, C type 2
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NPEPL1 aminopeptidase-like 1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUP214 nucleoporin 214kDa
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PADI1 peptidyl arginine deiminase, type I
PDE8B phosphodiesterase 8B
PELP1 proline, glutamate and leucine rich protein 1
PHF3 PHD finger protein 3
PLCG1 phospholipase C, gamma 1
PLD2 phospholipase D2
PRB1 proline-rich protein BstNI subfamily 1
PRODH2 proline dehydrogenase (oxidase) 2
PSEN2 presenilin 2
RAB2A RAB2A, member RAS oncogene family
RAB40B RAB40B, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RARA retinoic acid receptor, alpha
RNF39 ring finger protein 39
RXRA retinoid X receptor, alpha
S100A1 S100 calcium binding protein A1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SFN stratifin
SH2D1A SH2 domain containing 1A
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SPAG9 sperm associated antigen 9
SPDEF SAM pointed domain containing ETS transcription factor
SPTB spectrin, beta, erythrocytic
TBXA2R thromboxane A2 receptor
TMCC2 transmembrane and coiled-coil domain family 2
TTF2 transcription termination factor, RNA polymerase II
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TYR tyrosinase
UBTD1 ubiquitin domain containing 1
VGF VGF nerve growth factor inducible
VIPR2 vasoactive intestinal peptide receptor 2
WIPI2 WD repeat domain, phosphoinositide interacting 2
ZC3H13 zinc finger CCCH-type containing 13
ZC3H7B zinc finger CCCH-type containing 7B
ZFHX2 zinc finger homeobox 2
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACACA acetyl-CoA carboxylase alpha
ADAM15 ADAM metallopeptidase domain 15
AES amino-terminal enhancer of split
APOC2 apolipoprotein C-II
ARL4A ADP-ribosylation factor-like 4A
ASB6 ankyrin repeat and SOCS box containing 6
AVEN apoptosis, caspase activation inhibitor
BCL7B B-cell CLL/lymphoma 7B
BCL7C B-cell CLL/lymphoma 7C
CAPN1 calpain 1, (mu/I) large subunit
CCDC53 coiled-coil domain containing 53
CCL2 chemokine (C-C motif) ligand 2
CCNT1 cyclin T1
CD151 CD151 molecule (Raph blood group)
CLTCL1 clathrin, heavy chain-like 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DPF2 D4, zinc and double PHD fingers family 2
EMC9 ER membrane protein complex subunit 9
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
ERCC2 excision repair cross-complementation group 2
ERO1L ERO1-like (S. cerevisiae)
FHL3 four and a half LIM domains 3
GAB2 GRB2-associated binding protein 2
GBAP1 glucosidase, beta, acid pseudogene 1
GOLPH3L golgi phosphoprotein 3-like
H1FX H1 histone family, member X
IFITM3 interferon induced transmembrane protein 3
IRF9 interferon regulatory factor 9
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
JMJD4 jumonji domain containing 4
KIAA0753 KIAA0753
KLHL21 kelch-like family member 21
LAMP5 lysosomal-associated membrane protein family, member 5
LINC00339 long intergenic non-protein coding RNA 339
MAPKBP1 mitogen-activated protein kinase binding protein 1
MGMT O-6-methylguanine-DNA methyltransferase
MON1B MON1 secretory trafficking family member B
MPG N-methylpurine-DNA glycosylase
MYLIP myosin regulatory light chain interacting protein
NABP2 nucleic acid binding protein 2
NADSYN1 NAD synthetase 1
NCAPH non-SMC condensin I complex, subunit H
NDRG1 N-myc downstream regulated 1
NEU1 sialidase 1 (lysosomal sialidase)
NFE2 nuclear factor, erythroid 2
NLRX1 NLR family member X1
NRBP1 nuclear receptor binding protein 1
NVL nuclear VCP-like
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
ORC1 origin recognition complex, subunit 1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAGR1 PAXIP1 associated glutamate-rich protein 1
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PCTP phosphatidylcholine transfer protein
PEMT phosphatidylethanolamine N-methyltransferase
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKN1 protein kinase N1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POU2F1 POU class 2 homeobox 1
PPIEL peptidylprolyl isomerase E-like pseudogene
PRKCD protein kinase C, delta
PTOV1 prostate tumor overexpressed 1
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB4B RAB4B, member RAS oncogene family
RABEPK Rab9 effector protein with kelch motifs
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM10 RNA binding motif protein 10
RPUSD2 RNA pseudouridylate synthase domain containing 2
SAC3D1 SAC3 domain containing 1
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMG9 SMG9 nonsense mediated mRNA decay factor
SNX17 sorting nexin 17
SNX6 sorting nexin 6
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM106C transmembrane protein 106C
TMEM109 transmembrane protein 109
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSSC4 tumor suppressing subtransferable candidate 4
UFD1L ubiquitin fusion degradation 1 like (yeast)
USB1 U6 snRNA biogenesis 1
VILL villin-like
WBSCR16 Williams-Beuren syndrome chromosome region 16
WDR46 WD repeat domain 46
WDR6 WD repeat domain 6
YIPF1 Yip1 domain family, member 1
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC4 zinc finger, DHHC-type containing 4
ZNF32 zinc finger protein 32
ZNF395 zinc finger protein 395