danazol-5315 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the danazol-5315 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ANP32A-IT1 ANP32A intronic transcript 1
APOC1 apolipoprotein C-I
ARC activity-regulated cytoskeleton-associated protein
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARTN artemin
ATF3 activating transcription factor 3
ATG10 autophagy related 10
ATM ATM serine/threonine kinase
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CAPN15 calpain 15
CD44 CD44 molecule (Indian blood group)
CDHR2 cadherin-related family member 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNTN1 contactin 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DSCAM Down syndrome cell adhesion molecule
DTX4 deltex 4, E3 ubiquitin ligase
DYSF dysferlin
EGR1 early growth response 1
EGR3 early growth response 3
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EML3 echinoderm microtubule associated protein like 3
EPHA2 EPH receptor A2
FBXO22 F-box protein 22
FNDC3A fibronectin type III domain containing 3A
GAS7 growth arrest-specific 7
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GPRC5C G protein-coupled receptor, class C, group 5, member C
GRB10 growth factor receptor-bound protein 10
HCRP1 hepatocellular carcinoma-related HCRP1
HLA-F major histocompatibility complex, class I, F
HLA-J major histocompatibility complex, class I, J (pseudogene)
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMOX1 heme oxygenase 1
HSF1 heat shock transcription factor 1
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ISG20 interferon stimulated exonuclease gene 20kDa
KDM5C lysine (K)-specific demethylase 5C
KIAA0125 KIAA0125
LAMP1 lysosomal-associated membrane protein 1
MATK megakaryocyte-associated tyrosine kinase
MPST mercaptopyruvate sulfurtransferase
MRPS18C mitochondrial ribosomal protein S18C
MT1F metallothionein 1F
MT1H metallothionein 1H
N4BP3 NEDD4 binding protein 3
NAV2 neuron navigator 2
OASL 2'-5'-oligoadenylate synthetase-like
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCDHB3 protocadherin beta 3
PDE4DIP phosphodiesterase 4D interacting protein
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PELI1 pellino E3 ubiquitin protein ligase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRB1 proline-rich protein BstNI subfamily 1
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PTDSS2 phosphatidylserine synthase 2
QKI QKI, KH domain containing, RNA binding
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RNF126P1 ring finger protein 126 pseudogene 1
RPH3A rabphilin 3A
RPL7 ribosomal protein L7
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SH2D3A SH2 domain containing 3A
SH3BP2 SH3-domain binding protein 2
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMG5 SMG5 nonsense mediated mRNA decay factor
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAI2 snail family zinc finger 2
SOX9 SRY (sex determining region Y)-box 9
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRSF1 serine/arginine-rich splicing factor 1
STX7 syntaxin 7
SUGP1 SURP and G patch domain containing 1
TET3 tet methylcytosine dioxygenase 3
TM2D1 TM2 domain containing 1
TUBA3C tubulin, alpha 3c
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
WDR62 WD repeat domain 62
ZCCHC24 zinc finger, CCHC domain containing 24
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF710 zinc finger protein 710
ZSCAN26 zinc finger and SCAN domain containing 26

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ANKFY1 ankyrin repeat and FYVE domain containing 1
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARRB2 arrestin, beta 2
ATP7B ATPase, Cu++ transporting, beta polypeptide
BBC3 BCL2 binding component 3
BDH2 3-hydroxybutyrate dehydrogenase, type 2
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C11ORF68 chromosome 11 open reading frame 68
C2CD2 C2 calcium-dependent domain containing 2
CBR4 carbonyl reductase 4
CDR2L cerebellar degeneration-related protein 2-like
CENPQ centromere protein Q
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COMMD10 COMM domain containing 10
COPS7B COP9 signalosome subunit 7B
CORO1A coronin, actin binding protein, 1A
CYB5R1 cytochrome b5 reductase 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DCAF17 DDB1 and CUL4 associated factor 17
DENND1B DENN/MADD domain containing 1B
DHRS7B dehydrogenase/reductase (SDR family) member 7B
ECHDC2 enoyl CoA hydratase domain containing 2
EPHA4 EPH receptor A4
ERI3 ERI1 exoribonuclease family member 3
EVPL envoplakin
EXOC2 exocyst complex component 2
FCHSD2 FCH and double SH3 domains 2
FEM1C fem-1 homolog c (C. elegans)
FPGT fucose-1-phosphate guanylyltransferase
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FXR2 fragile X mental retardation, autosomal homolog 2
FYCO1 FYVE and coiled-coil domain containing 1
GFOD2 glucose-fructose oxidoreductase domain containing 2
GIPC1 GIPC PDZ domain containing family, member 1
GNPDA1 glucosamine-6-phosphate deaminase 1
HIST1H1D histone cluster 1, H1d
HIST1H2AG histone cluster 1, H2ag
HIST1H2AJ histone cluster 1, H2aj
HIST1H3H histone cluster 1, H3h
INTS9 integrator complex subunit 9
JADE1 jade family PHD finger 1
KIF18A kinesin family member 18A
KLHL26 kelch-like family member 26
KRBOX4 KRAB box domain containing 4
LMCD1 LIM and cysteine-rich domains 1
LMNB1 lamin B1
LRP5 low density lipoprotein receptor-related protein 5
MANBA mannosidase, beta A, lysosomal
MCMBP minichromosome maintenance complex binding protein
MTRF1 mitochondrial translational release factor 1
MYO9A myosin IXA
NARFL nuclear prelamin A recognition factor-like
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PEX13 peroxisomal biogenesis factor 13
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP6R3 protein phosphatase 6, regulatory subunit 3
PROS1 protein S (alpha)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RABL6 RAB, member RAS oncogene family-like 6
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM42 RNA binding motif protein 42
RCOR3 REST corepressor 3
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SMYD3 SET and MYND domain containing 3
SNHG20 small nucleolar RNA host gene 20
SOX12 SRY (sex determining region Y)-box 12
SPHK1 sphingosine kinase 1
STEAP3 STEAP family member 3, metalloreductase
STK16 serine/threonine kinase 16
STX5 syntaxin 5
SUN2 Sad1 and UNC84 domain containing 2
SYTL2 synaptotagmin-like 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM131 transmembrane protein 131
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TOLLIP toll interacting protein
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
VANGL1 VANGL planar cell polarity protein 1
VGF VGF nerve growth factor inducible
ZC3H12A zinc finger CCCH-type containing 12A
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF184 zinc finger protein 184
ZNF239 zinc finger protein 239
ZNF408 zinc finger protein 408
ZNF668 zinc finger protein 668