| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the dantrolene-2369 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD6 | abhydrolase domain containing 6 |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| AGXT | alanine-glyoxylate aminotransferase |
| APOA4 | apolipoprotein A-IV |
| APOL3 | apolipoprotein L, 3 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CAV2 | caveolin 2 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD52 | CD52 molecule |
| CD70 | CD70 molecule |
| CDK20 | cyclin-dependent kinase 20 |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) |
| CFHR4 | complement factor H-related 4 |
| CLDN17 | claudin 17 |
| COL6A1 | collagen, type VI, alpha 1 |
| COL9A1 | collagen, type IX, alpha 1 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CXXC4 | CXXC finger protein 4 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| EDNRB | endothelin receptor type B |
| EGR1 | early growth response 1 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| EML2 | echinoderm microtubule associated protein like 2 |
| EMX1 | empty spiracles homeobox 1 |
| EPYC | epiphycan |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| FGF4 | fibroblast growth factor 4 |
| FOXN3 | forkhead box N3 |
| FRMD4B | FERM domain containing 4B |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GIP | gastric inhibitory polypeptide |
| GNAS | GNAS complex locus |
| GRIP2 | glutamate receptor interacting protein 2 |
| HEYL | hes-related family bHLH transcription factor with YRPW motif-like |
| HN1L | hematological and neurological expressed 1-like |
| HOXA10 | homeobox A10 |
| IL12B | interleukin 12B |
| IL18RAP | interleukin 18 receptor accessory protein |
| IL4R | interleukin 4 receptor |
| IL5RA | interleukin 5 receptor, alpha |
| INO80D | INO80 complex subunit D |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| LAMA2 | laminin, alpha 2 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOXL3 | lysyl oxidase-like 3 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MIA | melanoma inhibitory activity |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MTMR3 | myotubularin related protein 3 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NNAT | neuronatin |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE12 | phosphodiesterase 12 |
| PEG3 | paternally expressed 3 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLCH1 | phospholipase C, eta 1 |
| PLXDC1 | plexin domain containing 1 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PVR | poliovirus receptor |
| RNF40 | ring finger protein 40, E3 ubiquitin protein ligase |
| RPH3A | rabphilin 3A |
| RYK | receptor-like tyrosine kinase |
| S100A13 | S100 calcium binding protein A13 |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SFTPB | surfactant protein B |
| SLC12A3 | solute carrier family 12 (sodium/chloride transporter), member 3 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SNTA1 | syntrophin, alpha 1 |
| SPHK2 | sphingosine kinase 2 |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| SSH3 | slingshot protein phosphatase 3 |
| STEAP4 | STEAP family member 4 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| TADA2A | transcriptional adaptor 2A |
| TAT | tyrosine aminotransferase |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCTA | T-cell leukemia translocation altered |
| TEF | thyrotrophic embryonic factor |
| TEK | TEK tyrosine kinase, endothelial |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEM40 | transmembrane protein 40 |
| TPMT | thiopurine S-methyltransferase |
| UBXN1 | UBX domain protein 1 |
| ZNF510 | zinc finger protein 510 |
| ZNF783 | zinc finger family member 783 |
| ZNF814 | zinc finger protein 814 |
| ZNF93 | zinc finger protein 93 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| AACS | acetoacetyl-CoA synthetase |
| ABHD4 | abhydrolase domain containing 4 |
| ACPP | acid phosphatase, prostate |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ANKRD36 | ankyrin repeat domain 36 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APH1B | APH1B gamma secretase subunit |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BCL7C | B-cell CLL/lymphoma 7C |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BOLA1 | bolA family member 1 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| C3 | complement component 3 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CEP70 | centrosomal protein 70kDa |
| CHKB | choline kinase beta |
| COPS7B | COP9 signalosome subunit 7B |
| CPTP | ceramide-1-phosphate transfer protein |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CSF1R | colony stimulating factor 1 receptor |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| EDAR | ectodysplasin A receptor |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ETAA1 | Ewing tumor-associated antigen 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM53B | family with sequence similarity 53, member B |
| FKBPL | FK506 binding protein like |
| GAB2 | GRB2-associated binding protein 2 |
| GPR22 | G protein-coupled receptor 22 |
| HIST1H2BE | histone cluster 1, H2be |
| HIST1H4J | histone cluster 1, H4j |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IL2RG | interleukin 2 receptor, gamma |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| IREB2 | iron-responsive element binding protein 2 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 |
| KIF3B | kinesin family member 3B |
| MAGEB2 | melanoma antigen family B2 |
| MANEA | mannosidase, endo-alpha |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| METTL16 | methyltransferase like 16 |
| MICA | MHC class I polypeptide-related sequence A |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MYL5 | myosin, light chain 5, regulatory |
| NCS1 | neuronal calcium sensor 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| PARG | poly (ADP-ribose) glycohydrolase |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| POMT1 | protein-O-mannosyltransferase 1 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PTCD1 | pentatricopeptide repeat domain 1 |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RAD9A | RAD9 homolog A (S. pombe) |
| RFXAP | regulatory factor X-associated protein |
| RINT1 | RAD50 interactor 1 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| SCRIB | scribbled planar cell polarity protein |
| SEPW1 | selenoprotein W, 1 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SPATA7 | spermatogenesis associated 7 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| SYNJ2BP | synaptojanin 2 binding protein |
| TASP1 | taspase, threonine aspartase, 1 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM254 | transmembrane protein 254 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TTC33 | tetratricopeptide repeat domain 33 |
| UBXN8 | UBX domain protein 8 |
| XAB2 | XPA binding protein 2 |
| XYLT1 | xylosyltransferase I |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF529 | zinc finger protein 529 |
| ZNF552 | zinc finger protein 552 |
| ZNF654 | zinc finger protein 654 |
