dantrolene-3978 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

196 genes differentially expressed following the dantrolene-3978 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACTA1 actin, alpha 1, skeletal muscle
ADAM12 ADAM metallopeptidase domain 12
ALOX15B arachidonate 15-lipoxygenase, type B
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
ARHGAP4 Rho GTPase activating protein 4
ART1 ADP-ribosyltransferase 1
BDKRB1 bradykinin receptor B1
BIRC3 baculoviral IAP repeat containing 3
C22ORF24 chromosome 22 open reading frame 24
C3AR1 complement component 3a receptor 1
C4BPA complement component 4 binding protein, alpha
CA9 carbonic anhydrase IX
CAMKV CaM kinase-like vesicle-associated
CAPN2 calpain 2, (m/II) large subunit
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC7 coiled-coil domain containing 7
CCL24 chemokine (C-C motif) ligand 24
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CEMP1 cementum protein 1
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLDN18 claudin 18
CLEC4A C-type lectin domain family 4, member A
CLSTN3 calsyntenin 3
DRD2 dopamine receptor D2
DUSP1 dual specificity phosphatase 1
EFCAB11 EF-hand calcium binding domain 11
EMX1 empty spiracles homeobox 1
ERICH1 glutamate-rich 1
FCGBP Fc fragment of IgG binding protein
FCMR Fc fragment of IgM receptor
FGF17 fibroblast growth factor 17
FGFBP1 fibroblast growth factor binding protein 1
FRMD8 FERM domain containing 8
FRS3 fibroblast growth factor receptor substrate 3
GLT8D2 glycosyltransferase 8 domain containing 2
GPR15 G protein-coupled receptor 15
GRM8 glutamate receptor, metabotropic 8
GYPB glycophorin B (MNS blood group)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HR hair growth associated
IL36RN interleukin 36 receptor antagonist
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
IZUMO4 IZUMO family member 4
KALRN kalirin, RhoGEF kinase
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KRT6B keratin 6B, type II
KRT8 keratin 8, type II
LECT1 leukocyte cell derived chemotaxin 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOXL3 lysyl oxidase-like 3
LUZP4 leucine zipper protein 4
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MEF2C myocyte enhancer factor 2C
MIER2 mesoderm induction early response 1, family member 2
MNMIP1 manchette microtubule inner protein 1
MOGAT2 monoacylglycerol O-acyltransferase 2
MRC2 mannose receptor, C type 2
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NPAS3 neuronal PAS domain protein 3
OXCT2 3-oxoacid CoA transferase 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCNXL2 pecanex-like 2 (Drosophila)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKNOX1 PBX/knotted 1 homeobox 1
POLL polymerase (DNA directed), lambda
PPARG peroxisome proliferator-activated receptor gamma
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRKCQ protein kinase C, theta
PTAFR platelet-activating factor receptor
RAB40A RAB40A, member RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBMS2 RNA binding motif, single stranded interacting protein 2
RBP4 retinol binding protein 4, plasma
REEP2 receptor accessory protein 2
RGCC regulator of cell cycle
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SIRPA signal-regulatory protein alpha
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPTBN1 spectrin, beta, non-erythrocytic 1
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TBX1 T-box 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TMOD1 tropomodulin 1
TMPRSS11D transmembrane protease, serine 11D
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TP63 tumor protein p63
TRIL TLR4 interactor with leucine-rich repeats
TUBA3C tubulin, alpha 3c
UBA7 ubiquitin-like modifier activating enzyme 7
UBR2 ubiquitin protein ligase E3 component n-recognin 2
WAS Wiskott-Aldrich syndrome
ZDHHC8P1 zinc finger, DHHC-type containing 8 pseudogene 1
ZNF711 zinc finger protein 711

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ACPP acid phosphatase, prostate
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AHSP alpha hemoglobin stabilizing protein
ARC activity-regulated cytoskeleton-associated protein
ARID3B AT rich interactive domain 3B (BRIGHT-like)
B9D2 B9 protein domain 2
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C11ORF30 chromosome 11 open reading frame 30
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CARTPT CART prepropeptide
CCDC134 coiled-coil domain containing 134
CCNK cyclin K
CCNO cyclin O
CD34 CD34 molecule
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEP41 centrosomal protein 41kDa
CES3 carboxylesterase 3
CFHR4 complement factor H-related 4
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLEC4E C-type lectin domain family 4, member E
CSF1R colony stimulating factor 1 receptor
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DNAH17 dynein, axonemal, heavy chain 17
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EMID1 EMI domain containing 1
FAM76A family with sequence similarity 76, member A
FBXO2 F-box protein 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FFAR2 free fatty acid receptor 2
FLJ11710 uncharacterized protein FLJ11710
FOXN2 forkhead box N2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAST gastrin
GATA4 GATA binding protein 4
GLB1L galactosidase, beta 1-like
GPR1 G protein-coupled receptor 1
GPRC5D G protein-coupled receptor, class C, group 5, member D
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HMHA1 histocompatibility (minor) HA-1
HMOX1 heme oxygenase 1
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HYAL1 hyaluronoglucosaminidase 1
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
INO80D INO80 complex subunit D
ITGA8 integrin, alpha 8
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0125 KIAA0125
KIF5A kinesin family member 5A
KLF8 Kruppel-like factor 8
LOC100131532 uncharacterized LOC100131532
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC15 leucine rich repeat containing 15
MALL mal, T-cell differentiation protein-like
MFGE8 milk fat globule-EGF factor 8 protein
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MX1 MX dynamin-like GTPase 1
NLRX1 NLR family member X1
NME5 NME/NM23 family member 5
NSUN6 NOP2/Sun domain family, member 6
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PRKG2 protein kinase, cGMP-dependent, type II
PYHIN1 pyrin and HIN domain family, member 1
RAB40AL RAB40A, member RAS oncogene family-like
RAB40C RAB40C, member RAS oncogene family
RIN1 Ras and Rab interactor 1
RND1 Rho family GTPase 1
RNF122 ring finger protein 122
RPH3A rabphilin 3A
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUSC2 RUN and SH3 domain containing 2
SAG S-antigen; retina and pineal gland (arrestin)
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC35G2 solute carrier family 35, member G2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SP4 Sp4 transcription factor
SRPX sushi-repeat containing protein, X-linked
STAC SH3 and cysteine rich domain
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TG thyroglobulin
TGFBR1 transforming growth factor, beta receptor 1
THBS3 thrombospondin 3
TLR1 toll-like receptor 1
TMEM180 transmembrane protein 180
ZNF112 zinc finger protein 112
ZNF155 zinc finger protein 155
ZNF343 zinc finger protein 343
ZNF484 zinc finger protein 484