| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the dantrolene-4343 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| AGFG2 | ArfGAP with FG repeats 2 |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| ANGPT1 | angiopoietin 1 |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| APAF1 | apoptotic peptidase activating factor 1 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ASPH | aspartate beta-hydroxylase |
| ATP10A | ATPase, class V, type 10A |
| BATF | basic leucine zipper transcription factor, ATF-like |
| CD48 | CD48 molecule |
| CDC14B | cell division cycle 14B |
| CLTCL1 | clathrin, heavy chain-like 1 |
| COL7A1 | collagen, type VII, alpha 1 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CTSZ | cathepsin Z |
| CYBB | cytochrome b-245, beta polypeptide |
| DCTN1 | dynactin 1 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOK2 | docking protein 2, 56kDa |
| DSCAM | Down syndrome cell adhesion molecule |
| EDN1 | endothelin 1 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| EZR | ezrin |
| FAM63A | family with sequence similarity 63, member A |
| FAM76A | family with sequence similarity 76, member A |
| FLT1 | fms-related tyrosine kinase 1 |
| FOXN2 | forkhead box N2 |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GOLGA8A | golgin A8 family, member A |
| GPX3 | glutathione peroxidase 3 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IDS | iduronate 2-sulfatase |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| INO80D | INO80 complex subunit D |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa |
| JAK3 | Janus kinase 3 |
| KIAA1024 | KIAA1024 |
| KIF5C | kinesin family member 5C |
| KIRREL | kin of IRRE like (Drosophila) |
| LOC100294391 | uncharacterized LOC100294391 |
| MED18 | mediator complex subunit 18 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NPEPPS | aminopeptidase puromycin sensitive |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| ONECUT2 | one cut homeobox 2 |
| PAPPA2 | pappalysin 2 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| POU2F3 | POU class 2 homeobox 3 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRO2012 | uncharacterized protein PRO2012 |
| RAB2A | RAB2A, member RAS oncogene family |
| RANBP1 | RAN binding protein 1 |
| RASL11B | RAS-like, family 11, member B |
| RBM26 | RNA binding motif protein 26 |
| RPLP2 | ribosomal protein, large, P2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SF1 | splicing factor 1 |
| SMAD5 | SMAD family member 5 |
| SMAD6 | SMAD family member 6 |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| THRA | thyroid hormone receptor, alpha |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZC3H11A | zinc finger CCCH-type containing 11A |
| ZIM2 | zinc finger, imprinted 2 |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZNF235 | zinc finger protein 235 |
| ZNF236 | zinc finger protein 236 |
| ZNF334 | zinc finger protein 334 |
| ZNF639 | zinc finger protein 639 |
| ZNF667 | zinc finger protein 667 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| APOL6 | apolipoprotein L, 6 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARRB2 | arrestin, beta 2 |
| ARSA | arylsulfatase A |
| AXIN1 | axin 1 |
| BEST2 | bestrophin 2 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CA9 | carbonic anhydrase IX |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CD101 | CD101 molecule |
| CD70 | CD70 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EPHA7 | EPH receptor A7 |
| EPN1 | epsin 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FBRS | fibrosin |
| FKBP5 | FK506 binding protein 5 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FLT4 | fms-related tyrosine kinase 4 |
| FZD10 | frizzled class receptor 10 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GLB1L | galactosidase, beta 1-like |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GTF2I | general transcription factor IIi |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| H1F0 | H1 histone family, member 0 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| IL2 | interleukin 2 |
| INCENP | inner centromere protein antigens 135/155kDa |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLHL25 | kelch-like family member 25 |
| KLHL36 | kelch-like family member 36 |
| LIMD2 | LIM domain containing 2 |
| LRRC15 | leucine rich repeat containing 15 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MMRN2 | multimerin 2 |
| MUC3B | mucin 3B, cell surface associated |
| MVD | mevalonate (diphospho) decarboxylase |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| OCLN | occludin |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OSBP2 | oxysterol binding protein 2 |
| OSMR | oncostatin M receptor |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAQR5 | progestin and adipoQ receptor family member V |
| PCDHA5 | protocadherin alpha 5 |
| PDE5A | phosphodiesterase 5A, cGMP-specific |
| PDE8B | phosphodiesterase 8B |
| PENK | proenkephalin |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PLBD1 | phospholipase B domain containing 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRSS53 | protease, serine, 53 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RFPL3 | ret finger protein-like 3 |
| RNF146 | ring finger protein 146 |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPRR2B | small proline-rich protein 2B |
| STRA6 | stimulated by retinoic acid 6 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TLN1 | talin 1 |
| TLR2 | toll-like receptor 2 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TRPV4 | transient receptor potential cation channel, subfamily V, member 4 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSPAN32 | tetraspanin 32 |
| TUBA3C | tubulin, alpha 3c |
| TUBA4B | tubulin, alpha 4b |
| VLDLR | very low density lipoprotein receptor |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF155 | zinc finger protein 155 |
| ZNF711 | zinc finger protein 711 |
| ZNF749 | zinc finger protein 749 |
| ZNF862 | zinc finger protein 862 |
| ZXDB | zinc finger, X-linked, duplicated B |
