| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the dapsone-1827 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| ANKRD12 | ankyrin repeat domain 12 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APH1A | APH1A gamma secretase subunit |
| APOL2 | apolipoprotein L, 2 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| AXL | AXL receptor tyrosine kinase |
| BAX | BCL2-associated X protein |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C17ORF85 | chromosome 17 open reading frame 85 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CD82 | CD82 molecule |
| CEP290 | centrosomal protein 290kDa |
| CHN2 | chimerin 2 |
| COG5 | component of oligomeric golgi complex 5 |
| COL4A6 | collagen, type IV, alpha 6 |
| CTSZ | cathepsin Z |
| CUL7 | cullin 7 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 |
| DLL3 | delta-like 3 (Drosophila) |
| EML2 | echinoderm microtubule associated protein like 2 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FDX1 | ferredoxin 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPR137 | G protein-coupled receptor 137 |
| HIRA | histone cell cycle regulator |
| HIST1H3G | histone cluster 1, H3g |
| HMOX1 | heme oxygenase 1 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFI44L | interferon-induced protein 44-like |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| JMJD6 | jumonji domain containing 6 |
| KIFC1 | kinesin family member C1 |
| KRT86 | keratin 86, type II |
| LARP4B | La ribonucleoprotein domain family, member 4B |
| LMNB1 | lamin B1 |
| LPIN2 | lipin 2 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| METTL3 | methyltransferase like 3 |
| MON1B | MON1 secretory trafficking family member B |
| MX1 | MX dynamin-like GTPase 1 |
| N4BP1 | NEDD4 binding protein 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NPEPL1 | aminopeptidase-like 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUP160 | nucleoporin 160kDa |
| PALMD | palmdelphin |
| PGAP1 | post-GPI attachment to proteins 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| RBM12 | RNA binding motif protein 12 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| RPL31 | ribosomal protein L31 |
| SERINC3 | serine incorporator 3 |
| SFTPB | surfactant protein B |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SLC25A44 | solute carrier family 25, member 44 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SRRM2 | serine/arginine repetitive matrix 2 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| SYK | spleen tyrosine kinase |
| TAZ | tafazzin |
| TBCD | tubulin folding cofactor D |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TFCP2 | transcription factor CP2 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TUBA3C | tubulin, alpha 3c |
| UTRN | utrophin |
| VEGFA | vascular endothelial growth factor A |
| WDR60 | WD repeat domain 60 |
| WWOX | WW domain containing oxidoreductase |
| ZFHX3 | zinc finger homeobox 3 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF286A | zinc finger protein 286A |
| ZNF358 | zinc finger protein 358 |
| ZNF580 | zinc finger protein 580 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALPK1 | alpha-kinase 1 |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CARD8 | caspase recruitment domain family, member 8 |
| CCNT1 | cyclin T1 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CFD | complement factor D (adipsin) |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHMP6 | charged multivesicular body protein 6 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN15 | claudin 15 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DCLRE1B | DNA cross-link repair 1B |
| DEAF1 | DEAF1 transcription factor |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| EDN1 | endothelin 1 |
| EFNA3 | ephrin-A3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM53B | family with sequence similarity 53, member B |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FZD8 | frizzled class receptor 8 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GALK1 | galactokinase 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMIP | GEM interacting protein |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPX2 | glutathione peroxidase 2 |
| GTPBP3 | GTP binding protein 3 (mitochondrial) |
| HIST1H2AG | histone cluster 1, H2ag |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| HYI | hydroxypyruvate isomerase (putative) |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| JAM3 | junctional adhesion molecule 3 |
| KCNJ12 | potassium channel, inwardly rectifying subfamily J, member 12 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIFC3 | kinesin family member C3 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MACROD1 | MACRO domain containing 1 |
| MAL | mal, T-cell differentiation protein |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MUC3A | mucin 3A, cell surface associated |
| MXRA8 | matrix-remodelling associated 8 |
| NCS1 | neuronal calcium sensor 1 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NPR3 | natriuretic peptide receptor 3 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PLD3 | phospholipase D family, member 3 |
| PMCH | pro-melanin-concentrating hormone |
| POLH | polymerase (DNA directed), eta |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RIN1 | Ras and Rab interactor 1 |
| RNF2 | ring finger protein 2 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SHPK | sedoheptulokinase |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC44A4 | solute carrier family 44, member 4 |
| SMA4 | glucuronidase, beta pseudogene |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPATA2L | spermatogenesis associated 2-like |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| TAGLN3 | transgelin 3 |
| TMEM132A | transmembrane protein 132A |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UNKL | unkempt family zinc finger-like |
| ZNF574 | zinc finger protein 574 |