dapsone-1868 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the dapsone-1868 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALS2CL ALS2 C-terminal like
APP amyloid beta (A4) precursor protein
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATP9B ATPase, class II, type 9B
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCAP29 B-cell receptor-associated protein 29
BPI bactericidal/permeability-increasing protein
BTG2 BTG family, member 2
C5ORF45 chromosome 5 open reading frame 45
C6ORF47 chromosome 6 open reading frame 47
CAPN15 calpain 15
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC106 coiled-coil domain containing 106
CCDC57 coiled-coil domain containing 57
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CECR1 cat eye syndrome chromosome region, candidate 1
CEP164 centrosomal protein 164kDa
CLEC4A C-type lectin domain family 4, member A
CSF1 colony stimulating factor 1 (macrophage)
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CTDNEP1 CTD nuclear envelope phosphatase 1
DAPK3 death-associated protein kinase 3
DBT dihydrolipoamide branched chain transacylase E2
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56
DHODH dihydroorotate dehydrogenase (quinone)
DLG4 discs, large homolog 4 (Drosophila)
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ELOVL5 ELOVL fatty acid elongase 5
EMILIN2 elastin microfibril interfacer 2
FAM102A family with sequence similarity 102, member A
FAM160B2 family with sequence similarity 160, member B2
FAS Fas cell surface death receptor
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FSCN1 fascin actin-bundling protein 1
FUZ fuzzy planar cell polarity protein
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GLP1R glucagon-like peptide 1 receptor
GRIP2 glutamate receptor interacting protein 2
HEXIM1 hexamethylene bis-acetamide inducible 1
HIST1H2AM histone cluster 1, H2am
ICAM2 intercellular adhesion molecule 2
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IQCK IQ motif containing K
KIAA0894 KIAA0894 protein
KIAA1024 KIAA1024
KMT2A lysine (K)-specific methyltransferase 2A
KRIT1 KRIT1, ankyrin repeat containing
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMP1 lysosomal-associated membrane protein 1
LDLR low density lipoprotein receptor
LIG4 ligase IV, DNA, ATP-dependent
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRRC37A2 leucine rich repeat containing 37, member A2
MAPK7 mitogen-activated protein kinase 7
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MED28 mediator complex subunit 28
MYH14 myosin, heavy chain 14, non-muscle
MZT2B mitotic spindle organizing protein 2B
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NIPAL2 NIPA-like domain containing 2
OGFR opioid growth factor receptor
PDLIM7 PDZ and LIM domain 7 (enigma)
PHTF2 putative homeodomain transcription factor 2
PIAS4 protein inhibitor of activated STAT, 4
PICALM phosphatidylinositol binding clathrin assembly protein
POFUT1 protein O-fucosyltransferase 1
PRUNE prune exopolyphosphatase
RAB2A RAB2A, member RAS oncogene family
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RDX radixin
RNGTT RNA guanylyltransferase and 5'-phosphatase
S100A12 S100 calcium binding protein A12
SC5D sterol-C5-desaturase
SELPLG selectin P ligand
SGSM3 small G protein signaling modulator 3
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SMG7 SMG7 nonsense mediated mRNA decay factor
SNX13 sorting nexin 13
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
SUGP1 SURP and G patch domain containing 1
SYNGR1 synaptogyrin 1
SYNJ1 synaptojanin 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAOK2 TAO kinase 2
TET3 tet methylcytosine dioxygenase 3
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TOB2 transducer of ERBB2, 2
TTLL1 tubulin tyrosine ligase-like family member 1
ZEB1 zinc finger E-box binding homeobox 1
ZFX zinc finger protein, X-linked
ZNF589 zinc finger protein 589
ZNF710 zinc finger protein 710
ZNF816 zinc finger protein 816

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AGO2 argonaute RISC catalytic component 2
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALPK1 alpha-kinase 1
ANKRD40 ankyrin repeat domain 40
ARRB1 arrestin, beta 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BCORL1 BCL6 corepressor-like 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTBD2 BTB (POZ) domain containing 2
C17ORF70 chromosome 17 open reading frame 70
C17ORF75 chromosome 17 open reading frame 75
C21ORF91 chromosome 21 open reading frame 91
C4ORF29 chromosome 4 open reading frame 29
CALCOCO1 calcium binding and coiled-coil domain 1
CARM1 coactivator-associated arginine methyltransferase 1
COL15A1 collagen, type XV, alpha 1
DBF4B DBF4 zinc finger B
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DHRS9 dehydrogenase/reductase (SDR family) member 9
DTX4 deltex 4, E3 ubiquitin ligase
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGR2 early growth response 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERO1LB ERO1-like beta (S. cerevisiae)
FAM114A1 family with sequence similarity 114, member A1
FAM188A family with sequence similarity 188, member A
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FICD FIC domain containing
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR85 G protein-coupled receptor 85
GUSBP3 glucuronidase, beta pseudogene 3
HPSE heparanase
HSPA4L heat shock 70kDa protein 4-like
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KIAA0319L KIAA0319-like
KIF13B kinesin family member 13B
KLK5 kallikrein-related peptidase 5
KPTN kaptin (actin binding protein)
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LINC00260 long intergenic non-protein coding RNA 260
LMAN2L lectin, mannose-binding 2-like
LPPR3 lipid phosphate phosphatase-related protein type 3
LRRC37A3 leucine rich repeat containing 37, member A3
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MBOAT2 membrane bound O-acyltransferase domain containing 2
MINPP1 multiple inositol-polyphosphate phosphatase 1
MOCS3 molybdenum cofactor synthesis 3
MRPL44 mitochondrial ribosomal protein L44
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NINJ2 ninjurin 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCSK7 proprotein convertase subtilisin/kexin type 7
PDCL phosducin-like
PIR pirin (iron-binding nuclear protein)
PYGB phosphorylase, glycogen; brain
QTRT1 queuine tRNA-ribosyltransferase 1
RAB23 RAB23, member RAS oncogene family
RARS arginyl-tRNA synthetase
RNF126P1 ring finger protein 126 pseudogene 1
RNF141 ring finger protein 141
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPS21 ribosomal protein S21
SNHG20 small nucleolar RNA host gene 20
SPATS2 spermatogenesis associated, serine-rich 2
SRD5A3 steroid 5 alpha-reductase 3
STBD1 starch binding domain 1
STXBP1 syntaxin binding protein 1
SURF2 surfeit 2
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TASP1 taspase, threonine aspartase, 1
TCTN2 tectonic family member 2
TGFBR3 transforming growth factor, beta receptor III
TMEM156 transmembrane protein 156
TNNT1 troponin T type 1 (skeletal, slow)
TRAF1 TNF receptor-associated factor 1
TTPAL tocopherol (alpha) transfer protein-like
TUFT1 tuftelin 1
TWIST1 twist family bHLH transcription factor 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UEVLD UEV and lactate/malate dehyrogenase domains
URGCP upregulator of cell proliferation
USB1 U6 snRNA biogenesis 1
USP6 ubiquitin specific peptidase 6
WT1-AS WT1 antisense RNA
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862