dapsone-5078 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the dapsone-5078 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACAN aggrecan
ACSBG2 acyl-CoA synthetase bubblegum family member 2
AGXT alanine-glyoxylate aminotransferase
AMOT angiomotin
BTG2 BTG family, member 2
CARD10 caspase recruitment domain family, member 10
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC181 coiled-coil domain containing 181
CCDC87 coiled-coil domain containing 87
CCL27 chemokine (C-C motif) ligand 27
CD7 CD7 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDY1 chromodomain protein, Y-linked, 1
CELP carboxyl ester lipase pseudogene
CLDN17 claudin 17
CLEC10A C-type lectin domain family 10, member A
COL14A1 collagen, type XIV, alpha 1
COL21A1 collagen, type XXI, alpha 1
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
EMID1 EMI domain containing 1
FABP3 fatty acid binding protein 3, muscle and heart
FAIM2 Fas apoptotic inhibitory molecule 2
FGB fibrinogen beta chain
FGFR2 fibroblast growth factor receptor 2
FOXP3 forkhead box P3
GREM2 gremlin 2, DAN family BMP antagonist
HBS1L HBS1-like translational GTPase
HDC histidine decarboxylase
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXB6 homeobox B6
HOXD13 homeobox D13
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IBSP integrin-binding sialoprotein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL1R1 interleukin 1 receptor, type I
IQCK IQ motif containing K
JAM2 junctional adhesion molecule 2
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KIF25-AS1 KIF25 antisense RNA 1
KLHL22 kelch-like family member 22
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LIME1 Lck interacting transmembrane adaptor 1
LRRTM2 leucine rich repeat transmembrane neuronal 2
MGAM maltase-glucoamylase
MGC2889 uncharacterized protein MGC2889
MMP13 matrix metallopeptidase 13
MOBP myelin-associated oligodendrocyte basic protein
MST1 macrophage stimulating 1
MTSS1L metastasis suppressor 1-like
NAT6 N-acetyltransferase 6 (GCN5-related)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NLGN1 neuroligin 1
NRG1 neuregulin 1
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM4 PDZ and LIM domain 4
PLIN2 perilipin 2
PMFBP1 polyamine modulated factor 1 binding protein 1
PPP1R17 protein phosphatase 1, regulatory subunit 17
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRLR prolactin receptor
PRMT2IP PRMT2 interacting protein
PRR5 proline rich 5 (renal)
PSD4 pleckstrin and Sec7 domain containing 4
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAG2 recombination activating gene 2
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RAPSN receptor-associated protein of the synapse
RETN resistin
SCAI suppressor of cancer cell invasion
SCGB2A1 secretoglobin, family 2A, member 1
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPRR1A small proline-rich protein 1A
SRSF7 serine/arginine-rich splicing factor 7
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TMPRSS2 transmembrane protease, serine 2
TOX thymocyte selection-associated high mobility group box
TPM1 tropomyosin 1 (alpha)
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZCCHC4 zinc finger, CCHC domain containing 4
ZFP2 ZFP2 zinc finger protein

decreased expression

Symbol Name
ADCY6 adenylate cyclase 6
ADGRG2 adhesion G protein-coupled receptor G2
AFAP1 actin filament associated protein 1
AK5 adenylate kinase 5
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOLD1 apolipoprotein L domain containing 1
ARL14 ADP-ribosylation factor-like 14
ASB7 ankyrin repeat and SOCS box containing 7
BCL2L2 BCL2-like 2
C4ORF29 chromosome 4 open reading frame 29
CASZ1 castor zinc finger 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC68 coiled-coil domain containing 68
CFAP44 cilia and flagella associated protein 44
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
CXCL3 chemokine (C-X-C motif) ligand 3
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
EFCAB2 EF-hand calcium binding domain 2
EMD emerin
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GDAP1 ganglioside induced differentiation associated protein 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GMEB1 glucocorticoid modulatory element binding protein 1
GPC3 glypican 3
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
H2AFJ H2A histone family, member J
HIST1H3C histone cluster 1, H3c
HIST1H4C histone cluster 1, H4c
HOOK1 hook microtubule-tethering protein 1
HOXA1 homeobox A1
HOXC10 homeobox C10
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IER3IP1 immediate early response 3 interacting protein 1
IFI6 interferon, alpha-inducible protein 6
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL17RA interleukin 17 receptor A
INF2 inverted formin, FH2 and WH2 domain containing
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0754 KIAA0754
KLF7 Kruppel-like factor 7 (ubiquitous)
LMO7 LIM domain 7
LOC100286895 cell division cycle 27 homolog pseudogene
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LY6G5C lymphocyte antigen 6 complex, locus G5C
LYPD1 LY6/PLAUR domain containing 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MCMBP minichromosome maintenance complex binding protein
MGC12488
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NID2 nidogen 2 (osteonidogen)
NINJ1 ninjurin 1
NOD1 nucleotide-binding oligomerization domain containing 1
OPLAH 5-oxoprolinase (ATP-hydrolysing)
P3H1 prolyl 3-hydroxylase 1
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PCDHGB5 protocadherin gamma subfamily B, 5
PDLIM2 PDZ and LIM domain 2 (mystique)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRKCE protein kinase C, epsilon
PRR4 proline rich 4 (lacrimal)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RIN1 Ras and Rab interactor 1
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SERGEF secretion regulating guanine nucleotide exchange factor
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT2 sirtuin 2
SLC35F6 solute carrier family 35, member F6
SMAD7 SMAD family member 7
SNRK SNF related kinase
SPTBN2 spectrin, beta, non-erythrocytic 2
STAG3 stromal antigen 3
STK4 serine/threonine kinase 4
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TEX40 testis expressed 40
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM2 transmembrane protein 2
TOM1 target of myb1 (chicken)
TSPAN8 tetraspanin 8
WDR76 WD repeat domain 76
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF204P zinc finger protein 204, pseudogene
ZNF264 zinc finger protein 264
ZNF34 zinc finger protein 34
ZNF480 zinc finger protein 480
ZNF668 zinc finger protein 668
ZNF76 zinc finger protein 76
ZNF767P zinc finger family member 767, pseudogene
ZNF83 zinc finger protein 83
ZNF862 zinc finger protein 862