dapsone-5498 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the dapsone-5498 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTL8 actin-like 8
ADGRL1 adhesion G protein-coupled receptor L1
AFF2 AF4/FMR2 family, member 2
AGMAT agmatine ureohydrolase (agmatinase)
AIF1 allograft inflammatory factor 1
ALS2CL ALS2 C-terminal like
ANP32A-IT1 ANP32A intronic transcript 1
APC adenomatous polyposis coli
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ASIC1 acid sensing (proton gated) ion channel 1
BCR breakpoint cluster region
BHLHE41 basic helix-loop-helix family, member e41
C2 complement component 2
C8ORF44 chromosome 8 open reading frame 44
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC93 coiled-coil domain containing 93
CD44 CD44 molecule (Indian blood group)
CDK14 cyclin-dependent kinase 14
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CEP41 centrosomal protein 41kDa
CHN2 chimerin 2
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CLCA1 chloride channel accessory 1
CNN2 calponin 2
COBLL1 cordon-bleu WH2 repeat protein-like 1
CPED1 cadherin-like and PC-esterase domain containing 1
CTBP2 C-terminal binding protein 2
CYB561 cytochrome b561
DAPK3 death-associated protein kinase 3
DTNA dystrobrevin, alpha
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EDAR ectodysplasin A receptor
EGFR epidermal growth factor receptor
EPOR erythropoietin receptor
EVI5 ecotropic viral integration site 5
FAM110B family with sequence similarity 110, member B
FDPS farnesyl diphosphate synthase
FGFR1 fibroblast growth factor receptor 1
FOXE1 forkhead box E1
HBEGF heparin-binding EGF-like growth factor
HP1BP3 heterochromatin protein 1, binding protein 3
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGHA1 immunoglobulin heavy constant alpha 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
ING2 inhibitor of growth family, member 2
INPP5K inositol polyphosphate-5-phosphatase K
IPO8 importin 8
ISL1 ISL LIM homeobox 1
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KLF12 Kruppel-like factor 12
LMOD1 leiomodin 1 (smooth muscle)
LOC257152 uncharacterized LOC257152
LRP6 low density lipoprotein receptor-related protein 6
LRRC17 leucine rich repeat containing 17
MAP2K2 mitogen-activated protein kinase kinase 2
MED31 mediator complex subunit 31
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MTAP methylthioadenosine phosphorylase
MTMR2 myotubularin related protein 2
MYL10 myosin, light chain 10, regulatory
NCAPH2 non-SMC condensin II complex, subunit H2
NF2 neurofibromin 2 (merlin)
OSGIN2 oxidative stress induced growth inhibitor family member 2
OSMR oncostatin M receptor
OTUD4 OTU deubiquitinase 4
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE1B phosphodiesterase 1B, calmodulin-dependent
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PTBP3 polypyrimidine tract binding protein 3
PTCRA pre T-cell antigen receptor alpha
PVR poliovirus receptor
RASL11B RAS-like, family 11, member B
RBM26 RNA binding motif protein 26
RERE arginine-glutamic acid dipeptide (RE) repeats
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RPL35A ribosomal protein L35a
S100A4 S100 calcium binding protein A4
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SH3BP2 SH3-domain binding protein 2
SKA1 spindle and kinetochore associated complex subunit 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SNX13 sorting nexin 13
SOGA1 suppressor of glucose, autophagy associated 1
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SREBF2 sterol regulatory element binding transcription factor 2
STAT5B signal transducer and activator of transcription 5B
STX5 syntaxin 5
STXBP5L syntaxin binding protein 5-like
TGFBR3 transforming growth factor, beta receptor III
TMEM209 transmembrane protein 209
TMEM259 transmembrane protein 259
TMPRSS3 transmembrane protease, serine 3
TSPAN32 tetraspanin 32
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZBTB22 zinc finger and BTB domain containing 22
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF286A zinc finger protein 286A
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
AFF4 AF4/FMR2 family, member 4
ALPK1 alpha-kinase 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA1 annexin A1
ARMC4 armadillo repeat containing 4
ARSB arylsulfatase B
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCL2L2 BCL2-like 2
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC85C coiled-coil domain containing 85C
CDK9 cyclin-dependent kinase 9
CENPO centromere protein O
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CRELD1 cysteine-rich with EGF-like domains 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAL4 dynein, axonemal, light chain 4
ERN2 endoplasmic reticulum to nucleus signaling 2
EVPL envoplakin
FAM155A family with sequence similarity 155, member A
FAM186A family with sequence similarity 186, member A
FAM204A family with sequence similarity 204, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
GPR19 G protein-coupled receptor 19
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HOXC8 homeobox C8
IDI2-AS1 IDI2 antisense RNA 1
INO80D INO80 complex subunit D
ITPKB inositol-trisphosphate 3-kinase B
ITPKC inositol-trisphosphate 3-kinase C
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KRT13 keratin 13, type I
KRT24 keratin 24, type I
KRT31 keratin 31, type I
LHFPL2 lipoma HMGIC fusion partner-like 2
LMNB1 lamin B1
LOC100286895 cell division cycle 27 homolog pseudogene
LRRTM2 leucine rich repeat transmembrane neuronal 2
LYPLA2P1 lysophospholipase II pseudogene 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MED9 mediator complex subunit 9
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MUC3A mucin 3A, cell surface associated
MXD3 MAX dimerization protein 3
MYOZ3 myozenin 3
NHEJ1 nonhomologous end-joining factor 1
NIPAL2 NIPA-like domain containing 2
NKAIN1 Na+/K+ transporting ATPase interacting 1
PADI1 peptidyl arginine deiminase, type I
PCDHB3 protocadherin beta 3
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLSCR4 phospholipid scramblase 4
POLH polymerase (DNA directed), eta
POLL polymerase (DNA directed), lambda
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRF1 perforin 1 (pore forming protein)
PRSS16 protease, serine, 16 (thymus)
PRSS22 protease, serine, 22
RASA2 RAS p21 protein activator 2
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF122 ring finger protein 122
ROM1 retinal outer segment membrane protein 1
RPAP1 RNA polymerase II associated protein 1
SH3BGR SH3 domain binding glutamate-rich protein
SIRT2 sirtuin 2
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SNAI2 snail family zinc finger 2
SPIDR scaffolding protein involved in DNA repair
SPINK4 serine peptidase inhibitor, Kazal type 4
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STIM1 stromal interaction molecule 1
STX1A syntaxin 1A (brain)
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
THAP7 THAP domain containing 7
TMEM57 transmembrane protein 57
TRAPPC11 trafficking protein particle complex 11
TUBA3D tubulin, alpha 3d
UBQLN4 ubiquilin 4
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
UPK3B uroplakin 3B
USB1 U6 snRNA biogenesis 1
VGF VGF nerve growth factor inducible
WDR91 WD repeat domain 91
WLS wntless Wnt ligand secretion mediator
ZNF442 zinc finger protein 442
ZNF492 zinc finger protein 492
ZNF516 zinc finger protein 516
ZNF767P zinc finger family member 767, pseudogene