death domain binding Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB. (Gene Ontology, GO_0070513)
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8 genes performing the death domain binding molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
DAP death-associated protein
MCL1 myeloid cell leukemia 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
TRADD TNFRSF1A-associated via death domain