death receptor binding Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with any member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD). (Gene Ontology, GO_0005123)
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16 genes performing the death receptor binding molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
BID BH3 interacting domain death agonist
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP8AP2 caspase 8 associated protein 2
CFLAR CASP8 and FADD-like apoptosis regulator
DAB2IP DAB2 interacting protein
FADD Fas (TNFRSF6)-associated via death domain
FASLG Fas ligand (TNF superfamily, member 6)
FEM1B fem-1 homolog b (C. elegans)
MADD MAP-kinase activating death domain
MYD88 myeloid differentiation primary response 88
NGF nerve growth factor (beta polypeptide)
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PIDD1 p53-induced death domain protein 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
TMBIM1 transmembrane BAX inhibitor motif containing 1
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15