debrisoquin Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

690 genes differentially expressed following the debrisoquin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TNIK TRAF2 and NCK interacting kinase 5.60482
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 5.57015
HLA-DOA major histocompatibility complex, class II, DO alpha 5.5597
SHTN1 shootin 1 5.43458
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 5.43439
TUBA1C tubulin, alpha 1c 5.33589
TEX15 testis expressed 15 5.2843
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 5.21883
TUBA1B tubulin, alpha 1b 5.18357
PRC1 protein regulator of cytokinesis 1 5.11527
FGF23 fibroblast growth factor 23 5.11357
NUSAP1 nucleolar and spindle associated protein 1 5.02786
LRP6 low density lipoprotein receptor-related protein 6 4.99181
CASP10 caspase 10, apoptosis-related cysteine peptidase 4.98972
KAT6B K(lysine) acetyltransferase 6B 4.97722
WHRN whirlin 4.90946
RPL8 ribosomal protein L8 4.82426
PMFBP1 polyamine modulated factor 1 binding protein 1 4.81253
IQCG IQ motif containing G 4.77694
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 4.76654
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 4.76501
ADAM19 ADAM metallopeptidase domain 19 4.74434
GSTM4 glutathione S-transferase mu 4 4.71327
MT2A metallothionein 2A 4.66207
AXIN1 axin 1 4.64686
SOX11 SRY (sex determining region Y)-box 11 4.60568
NCF4 neutrophil cytosolic factor 4, 40kDa 4.6022
RASA3 RAS p21 protein activator 3 4.60162
PDZRN3 PDZ domain containing ring finger 3 4.60094
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 4.5682
KCTD14 potassium channel tetramerization domain containing 14 4.5388
ZNF710 zinc finger protein 710 4.53735
HEATR6 HEAT repeat containing 6 4.53385
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 4.52491
PDK3 pyruvate dehydrogenase kinase, isozyme 3 4.51527
PLAT plasminogen activator, tissue 4.50827
STK26 serine/threonine protein kinase 26 4.49042
RPL28 ribosomal protein L28 4.47771
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 4.44997
UGT8 UDP glycosyltransferase 8 4.43427
TUBBP5 tubulin, beta pseudogene 5 4.43199
TRIM66 tripartite motif containing 66 4.39767
EFR3B EFR3 homolog B (S. cerevisiae) 4.38761
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 4.37974
WWTR1 WW domain containing transcription regulator 1 4.36567
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 4.35178
RPS14 ribosomal protein S14 4.34735
DYNLT3 dynein, light chain, Tctex-type 3 4.34137
SAA4 serum amyloid A4, constitutive 4.31589
PPP1R10 protein phosphatase 1, regulatory subunit 10 4.27639
WASHC4 WASH complex subunit 4 4.2745
RPS5 ribosomal protein S5 4.2745
DUSP22 dual specificity phosphatase 22 4.27013
AMOT angiomotin 4.24444
ADRB2 adrenoceptor beta 2, surface 4.23036
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 4.19764
CCNT1 cyclin T1 4.1774
ARMC9 armadillo repeat containing 9 4.15521
SHROOM2 shroom family member 2 4.14719
PEX2 peroxisomal biogenesis factor 2 4.1314
ANKRD17 ankyrin repeat domain 17 4.13011
CTNND1 catenin (cadherin-associated protein), delta 1 4.10324
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 4.10226
WLS wntless Wnt ligand secretion mediator 4.09267
CRISP1 cysteine-rich secretory protein 1 4.08231
COL11A2 collagen, type XI, alpha 2 4.07686
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 4.06016
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 4.04258
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 4.04011
GPX5 glutathione peroxidase 5 4.0345
MINDY1 MINDY lysine 48 deubiquitinase 1 4.02389
FGFR2 fibroblast growth factor receptor 2 4.02377
IRX5 iroquois homeobox 5 4.01739
STAT5B signal transducer and activator of transcription 5B 4.01627
UBA6 ubiquitin-like modifier activating enzyme 6 4.01371
LRRC17 leucine rich repeat containing 17 4.00069
CDCA4 cell division cycle associated 4 3.97691
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 3.95964
BCL7B B-cell CLL/lymphoma 7B 3.95858
CAPN6 calpain 6 3.94615
ZCCHC4 zinc finger, CCHC domain containing 4 3.93786
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 3.93743
SELPLG selectin P ligand 3.92258
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 3.92196
KLHL28 kelch-like family member 28 3.92032
LOC100130331 POTE ankyrin domain family, member F pseudogene 3.90892
CERS4 ceramide synthase 4 3.9021
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.8821
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 3.86905
EXTL2 exostosin-like glycosyltransferase 2 3.84803
ISOC1 isochorismatase domain containing 1 3.83813
NCF1C neutrophil cytosolic factor 1C pseudogene 3.83635
DLG3 discs, large homolog 3 (Drosophila) 3.83527
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 3.82386
FN3KRP fructosamine 3 kinase related protein 3.8172
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa 3.81564
MAST4 microtubule associated serine/threonine kinase family member 4 3.81527
PMP22 peripheral myelin protein 22 3.81525
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 3.8135
SINHCAF SIN3-HDAC complex associated factor 3.80393
PCDHGA10 protocadherin gamma subfamily A, 10 3.79336
THTPA thiamine triphosphatase 3.79292
AGFG1 ArfGAP with FG repeats 1 3.78532
RPL13 ribosomal protein L13 3.7849
DHDDS dehydrodolichyl diphosphate synthase 3.78239
NELL1 NEL-like 1 (chicken) 3.77975
FRMD4A FERM domain containing 4A 3.77958
GH2 growth hormone 2 3.77248
DDB2 damage-specific DNA binding protein 2, 48kDa 3.77145
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 3.76319
CST3 cystatin C 3.75826
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 3.75441
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 3.75432
PHKA2 phosphorylase kinase, alpha 2 (liver) 3.75389
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 3.75149
MAP3K19 mitogen-activated protein kinase kinase kinase 19 3.74787
PAXBP1 PAX3 and PAX7 binding protein 1 3.73306
SH3TC2 SH3 domain and tetratricopeptide repeats 2 3.72437
SUMO4 small ubiquitin-like modifier 4 3.71709
HDC histidine decarboxylase 3.71299
TAAR2 trace amine associated receptor 2 3.69933
DGKD diacylglycerol kinase, delta 130kDa 3.69538
SETBP1 SET binding protein 1 3.69152
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 3.69047
USP8 ubiquitin specific peptidase 8 3.66744
DMBT1 deleted in malignant brain tumors 1 3.64983
ALOX5 arachidonate 5-lipoxygenase 3.64709
PNMA8A PNMA family member 8A 3.63749
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 3.63644
ANXA2 annexin A2 3.61858
ARID3B AT rich interactive domain 3B (BRIGHT-like) 3.61818
CD22 CD22 molecule 3.6179
PAIP2B poly(A) binding protein interacting protein 2B 3.6113
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 3.60594
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 3.59881
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 3.58052
AMPD1 adenosine monophosphate deaminase 1 3.57968
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 3.5787
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 3.57236
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 3.57147
CXCR6 chemokine (C-X-C motif) receptor 6 3.56615
ZDHHC17 zinc finger, DHHC-type containing 17 3.56144
RPS3 ribosomal protein S3 3.55984
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 3.5517
GOLGA6A golgin A6 family, member A 3.54979
TRAPPC2L trafficking protein particle complex 2-like 3.54843
TFB1M transcription factor B1, mitochondrial 3.54837
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 3.54641
VPREB3 pre-B lymphocyte 3 3.54572
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 3.54167
FXYD6 FXYD domain containing ion transport regulator 6 3.53772
CUEDC1 CUE domain containing 1 3.53066
FAM193B family with sequence similarity 193, member B 3.52706
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 3.50378
EPN2 epsin 2 3.5035
KXD1 KxDL motif containing 1 3.49771
PCGF2 polycomb group ring finger 2 3.49755
ADGRG2 adhesion G protein-coupled receptor G2 3.49201
EPB41L5 erythrocyte membrane protein band 4.1 like 5 3.49169
TBCD tubulin folding cofactor D 3.47715
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 3.47225
IFITM3 interferon induced transmembrane protein 3 3.46933
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 3.46838
TXNIP thioredoxin interacting protein 3.46765
LIN7A lin-7 homolog A (C. elegans) 3.46351
ABHD6 abhydrolase domain containing 6 3.44903
TGFA transforming growth factor, alpha 3.44349
PRUNE1 prune exopolyphosphatase 1 3.44184
MKRN3 makorin ring finger protein 3 3.43988
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 3.43931
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 3.43594
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 3.42389
COLGALT2 collagen beta(1-O)galactosyltransferase 2 3.41297
AASS aminoadipate-semialdehyde synthase 3.41119
MEIS2 Meis homeobox 2 3.40582
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 3.39918
RAPSN receptor-associated protein of the synapse 3.3881
NPY1R neuropeptide Y receptor Y1 3.38044
SSX3 synovial sarcoma, X breakpoint 3 3.37883
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 3.37646
TRPC1 transient receptor potential cation channel, subfamily C, member 1 3.37516
NOS2 nitric oxide synthase 2, inducible 3.37162
PACC1 proton activated chloride channel 1 3.3697
COG4 component of oligomeric golgi complex 4 3.36622
TTC22 tetratricopeptide repeat domain 22 3.35064
FAM184A family with sequence similarity 184, member A 3.34387
ANG angiogenin, ribonuclease, RNase A family, 5 3.34227
MOB1A MOB kinase activator 1A 3.34031
DCAF13 DDB1 and CUL4 associated factor 13 3.33998
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 3.33762
MARCHF1 membrane associated ring-CH-type finger 1 3.33472
ARHGAP24 Rho GTPase activating protein 24 3.33068
CSNK1A1 casein kinase 1, alpha 1 3.32725
CLDN17 claudin 17 3.32576
NINL ninein-like 3.32439
RNF19B ring finger protein 19B 3.32201
SAV1 salvador family WW domain containing protein 1 3.32133
NR0B1 nuclear receptor subfamily 0, group B, member 1 3.31813
METTL25B methyltransferase like 25B 3.31133
EOLA2-DT EOLA2 divergent transcript 3.30938
RAP2C RAP2C, member of RAS oncogene family 3.2936
RRH retinal pigment epithelium-derived rhodopsin homolog 3.29264
TAS2R14 taste receptor, type 2, member 14 3.29171
SLF2 SMC5-SMC6 complex localization factor 2 3.29138
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 3.28822
SLCO1A2 solute carrier organic anion transporter family, member 1A2 3.28783
NAXD NAD(P)HX dehydratase 3.28573
ENPEP glutamyl aminopeptidase (aminopeptidase A) 3.2723
CPED1 cadherin-like and PC-esterase domain containing 1 3.27119
CAST calpastatin 3.27059
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 3.26727
CTNNBIP1 catenin, beta interacting protein 1 3.26253
ARFIP1 ADP-ribosylation factor interacting protein 1 3.26099
HSPA4L heat shock 70kDa protein 4-like 3.26047
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 3.25889
NT5DC3 5'-nucleotidase domain containing 3 3.25477
FMO1 flavin containing monooxygenase 1 3.24935
KIF3A kinesin family member 3A 3.24479
PAX6 paired box 6 3.24088
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 3.2369
JAM3 junctional adhesion molecule 3 3.23324
MGP matrix Gla protein 3.23132
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 3.22999
ICAM2 intercellular adhesion molecule 2 3.22962
STARD13 StAR-related lipid transfer (START) domain containing 13 3.22907
SUCO SUN domain containing ossification factor 3.22696
SYT11 synaptotagmin XI 3.22683
GRB14 growth factor receptor-bound protein 14 3.22184
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 3.21781
MKS1 Meckel syndrome, type 1 3.21592
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 3.21237
EMILIN2 elastin microfibril interfacer 2 3.20916
TBX6 T-box 6 3.20638
NRBP1 nuclear receptor binding protein 1 3.20551
HLA-DOB major histocompatibility complex, class II, DO beta 3.2035
GRP gastrin-releasing peptide 3.20191
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 3.19765
PKDREJ polycystin (PKD) family receptor for egg jelly 3.19247
MORC4 MORC family CW-type zinc finger 4 3.18808
FMO2 flavin containing monooxygenase 2 (non-functional) 3.18414
SAP30BP SAP30 binding protein 3.18204
TRAFD1 TRAF-type zinc finger domain containing 1 3.17955
MED14 mediator complex subunit 14 3.17922
RPL19 ribosomal protein L19 3.17885
DEFA5 defensin, alpha 5, Paneth cell-specific 3.17736
DET1 de-etiolated homolog 1 (Arabidopsis) 3.17136
NR2F2 nuclear receptor subfamily 2, group F, member 2 3.16836
TARDBP TAR DNA binding protein 3.1673
NCAPH2 non-SMC condensin II complex, subunit H2 3.16577
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 3.16102
KDM6A lysine (K)-specific demethylase 6A 3.16061
TEX14 testis expressed 14 3.15834
KDM5A lysine (K)-specific demethylase 5A 3.15595
WNT16 wingless-type MMTV integration site family, member 16 3.15507
ZNF609 zinc finger protein 609 3.14931
ZNF334 zinc finger protein 334 3.14728
GNB5 guanine nucleotide binding protein (G protein), beta 5 3.14653
MAGEB2 melanoma antigen family B2 3.14423
RPL13A ribosomal protein L13a 3.1425
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 3.13834
RPAP1 RNA polymerase II associated protein 1 3.13723
ZBTB20 zinc finger and BTB domain containing 20 3.13625
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 3.1359
TNS2 tensin 2 3.13378
RFPL2 ret finger protein-like 2 3.12824
CCDC7 coiled-coil domain containing 7 3.12813
DHRS1 dehydrogenase/reductase (SDR family) member 1 3.12549
FLI1 Fli-1 proto-oncogene, ETS transcription factor 3.1214
HMGB2 high mobility group box 2 3.1212
TTC17 tetratricopeptide repeat domain 17 3.11529
L1TD1 LINE-1 type transposase domain containing 1 3.11348
WDR59 WD repeat domain 59 3.10977
CTAGE9 CTAGE family, member 9 3.10662
CLMN calmin (calponin-like, transmembrane) 3.10447
GFPT2 glutamine-fructose-6-phosphate transaminase 2 3.09889
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 3.09769
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 3.0901
RAB11FIP5 RAB11 family interacting protein 5 (class I) 3.08691
SOCS1 suppressor of cytokine signaling 1 3.08416
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 3.08003
RBM12B RNA binding motif protein 12B 3.07525
RPRM reprimo, TP53 dependent G2 arrest mediator candidate 3.07142
WDFY3 WD repeat and FYVE domain containing 3 3.06923
KLK12 kallikrein-related peptidase 12 3.06846
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 3.06827
GDI1 GDP dissociation inhibitor 1 3.06633
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) 3.06612
COL11A1 collagen, type XI, alpha 1 3.0649
CRTAC1 cartilage acidic protein 1 3.06413
FXYD3 FXYD domain containing ion transport regulator 3 3.06062
TRIM38 tripartite motif containing 38 3.05398
OSBPL10 oxysterol binding protein-like 10 3.0535
C2 complement component 2 3.05321
NEK11 NIMA-related kinase 11 3.05071
ANKRD6 ankyrin repeat domain 6 3.0506
RHOB ras homolog family member B 3.05055
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 3.04965
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) 3.04843
PDZK1 PDZ domain containing 1 3.0483
ANXA13 annexin A13 3.0457
TCTN1 tectonic family member 1 3.04517
UBE2N ubiquitin-conjugating enzyme E2N 3.04123
LTBP1 latent transforming growth factor beta binding protein 1 3.04121
BBX bobby sox homolog (Drosophila) 3.04074
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 3.0407
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 3.03887
LGI2 leucine-rich repeat LGI family, member 2 3.0384
MFF mitochondrial fission factor 3.03674
SYNGR2 synaptogyrin 2 3.03655
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3 3.03611
TSPO translocator protein (18kDa) 3.03607
EML4 echinoderm microtubule associated protein like 4 3.03313
NASP nuclear autoantigenic sperm protein (histone-binding) 3.03267
GJA1 gap junction protein, alpha 1, 43kDa 3.03106
MAGEC1 melanoma antigen family C1 3.02972
CHD7 chromodomain helicase DNA binding protein 7 3.02833
RPL34 ribosomal protein L34 3.02688
MAPK10 mitogen-activated protein kinase 10 3.02664
KANSL3 KAT8 regulatory NSL complex subunit 3 3.02412
NPY5R neuropeptide Y receptor Y5 3.01885
ABI3BP ABI family, member 3 (NESH) binding protein 3.01309
LRRC20 leucine rich repeat containing 20 3.01254
CD300C CD300c molecule 3.00984
PPP1R9A protein phosphatase 1, regulatory subunit 9A 3.00805
CCL15 chemokine (C-C motif) ligand 15 3.0075
CLEC16A C-type lectin domain family 16, member A 3.00111
RABGAP1L RAB GTPase activating protein 1-like 3.00107

decreased expression

Symbol Name Standardized Value
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -7.23807
CEP57 centrosomal protein 57kDa -7.0467
BRCA1 breast cancer 1, early onset -6.95046
TICAM1 toll-like receptor adaptor molecule 1 -6.38335
DUSP14 dual specificity phosphatase 14 -5.83056
GLI2 GLI family zinc finger 2 -5.7868
MYCNOS MYCN opposite strand -5.78067
MAP7 microtubule-associated protein 7 -5.40543
JTB jumping translocation breakpoint -5.40351
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) -5.37527
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog -5.35003
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) -5.34811
CPT1A carnitine palmitoyltransferase 1A (liver) -5.33965
OCM2 oncomodulin 2 -5.24649
ARPP21 cAMP-regulated phosphoprotein, 21kDa -5.2271
FOXE1 forkhead box E1 -5.22084
GREM2 gremlin 2, DAN family BMP antagonist -5.19913
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -5.18756
TRIM58 tripartite motif containing 58 -5.13693
PRKCH protein kinase C, eta -5.04801
CD2AP CD2-associated protein -4.99546
STAT1 signal transducer and activator of transcription 1, 91kDa -4.98545
CLDN14 claudin 14 -4.94001
FOXN1 forkhead box N1 -4.91819
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) -4.89209
RUNX3 runt-related transcription factor 3 -4.89121
ACTR8 ARP8 actin-related protein 8 homolog (yeast) -4.8797
TRPM1 transient receptor potential cation channel, subfamily M, member 1 -4.87732
GNAT3 guanine nucleotide binding protein, alpha transducing 3 -4.81692
TLX2 T-cell leukemia homeobox 2 -4.79252
GUCA1A guanylate cyclase activator 1A (retina) -4.79031
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 -4.78698
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa -4.78237
DEDD death effector domain containing -4.75446
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -4.68399
GPR68 G protein-coupled receptor 68 -4.6781
CDH13 cadherin 13 -4.60661
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -4.59786
EPHB6 EPH receptor B6 -4.58688
GPR37L1 G protein-coupled receptor 37 like 1 -4.56697
XPA xeroderma pigmentosum, complementation group A -4.55756
MSI1 musashi RNA-binding protein 1 -4.55679
PNPO pyridoxamine 5'-phosphate oxidase -4.55307
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 -4.54322
PKP3 plakophilin 3 -4.52901
MYO7B myosin VIIB -4.51132
TMEM204 transmembrane protein 204 -4.50174
KCNK7 potassium channel, two pore domain subfamily K, member 7 -4.48013
IL23A interleukin 23, alpha subunit p19 -4.47669
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.45325
PLPPR4 phospholipid phosphatase related 4 -4.45008
TLE4 transducin-like enhancer of split 4 -4.42885
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 -4.40824
ZBTB7C zinc finger and BTB domain containing 7C -4.40729
CELA3B chymotrypsin-like elastase family, member 3B -4.39819
GLUD1 glutamate dehydrogenase 1 -4.38627
CD8B CD8b molecule -4.3644
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.36298
SDCBP syndecan binding protein (syntenin) -4.35738
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) -4.35425
TSHR thyroid stimulating hormone receptor -4.31467
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 -4.29481
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein -4.29092
IKZF1 IKAROS family zinc finger 1 (Ikaros) -4.27222
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -4.27177
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -4.27027
LIMS2 LIM and senescent cell antigen-like domains 2 -4.26881
NEUROG3 neurogenin 3 -4.25067
ZNF764 zinc finger protein 764 -4.24849
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain -4.24763
IRAK4 interleukin-1 receptor-associated kinase 4 -4.24633
AKAP5 A kinase (PRKA) anchor protein 5 -4.24511
DLD dihydrolipoamide dehydrogenase -4.22674
ADCY3 adenylate cyclase 3 -4.22132
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit -4.22017
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae) -4.21841
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -4.18823
GALR2 galanin receptor 2 -4.1678
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -4.16592
GCGR glucagon receptor -4.11613
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa -4.10652
AANAT aralkylamine N-acetyltransferase -4.1032
INPP5J inositol polyphosphate-5-phosphatase J -4.10188
UBXN6 UBX domain protein 6 -4.08533
BTF3P11 basic transcription factor 3 pseudogene 11 -4.07206
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 -4.07034
SORBS3 sorbin and SH3 domain containing 3 -4.06418
HIRA histone cell cycle regulator -4.04357
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 -4.03701
RAB11FIP1 RAB11 family interacting protein 1 (class I) -4.03
CCDC106 coiled-coil domain containing 106 -4.00781
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.99698
KRT9 keratin 9, type I -3.98799
ADM adrenomedullin -3.98123
CRK v-crk avian sarcoma virus CT10 oncogene homolog -3.97929
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 -3.96915
SCN3B sodium channel, voltage gated, type III beta subunit -3.93473
STC2 stanniocalcin 2 -3.93121
ENTREP3 endosomal transmembrane epsin interactor 3 -3.92607
GPR39 G protein-coupled receptor 39 -3.91171
TBX1 T-box 1 -3.90837
KRTAP5-9 keratin associated protein 5-9 -3.9055
RTCA RNA 3'-terminal phosphate cyclase -3.8883
CDR1 cerebellar degeneration-related protein 1, 34kDa -3.88155
HBQ1 hemoglobin, theta 1 -3.87845
FBXO9 F-box protein 9 -3.8764
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha -3.87477
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein -3.86381
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -3.85855
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 -3.85427
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -3.8441
LRRN3 leucine rich repeat neuronal 3 -3.83849
PRKN parkin RBR E3 ubiquitin protein ligase -3.83839
BEX3 brain expressed X-linked 3 -3.83519
CD248 CD248 molecule, endosialin -3.83475
OR7A17 olfactory receptor, family 7, subfamily A, member 17 -3.82956
KATNB1 katanin p80 (WD repeat containing) subunit B 1 -3.82428
MLNR motilin receptor -3.82248
NRXN2 neurexin 2 -3.82128
WBP4 WW domain binding protein 4 -3.81757
HRH3 histamine receptor H3 -3.81558
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -3.81024
ELN elastin -3.80352
TG thyroglobulin -3.80106
MRPL3 mitochondrial ribosomal protein L3 -3.80034
PDCD2 programmed cell death 2 -3.78404
STRAP serine/threonine kinase receptor associated protein -3.7795
IL6R interleukin 6 receptor -3.7778
RASA4 RAS p21 protein activator 4 -3.77041
IMPG1 interphotoreceptor matrix proteoglycan 1 -3.76466
DOT1L DOT1-like histone H3K79 methyltransferase -3.76105
H1-5 H1.5 linker histone, cluster member -3.75211
RIMS1 regulating synaptic membrane exocytosis 1 -3.74336
CARM1 coactivator-associated arginine methyltransferase 1 -3.74121
MGAT4C MGAT4 family, member C -3.74067
RAB9BP1 RAB9B, member RAS oncogene family pseudogene 1 -3.7349
QTRT1 queuine tRNA-ribosyltransferase 1 -3.73483
CTNNA2 catenin (cadherin-associated protein), alpha 2 -3.72777
CLDN7 claudin 7 -3.72185
H1-3 H1.3 linker histone, cluster member -3.72166
SYT5 synaptotagmin V -3.70446
CCDC90B coiled-coil domain containing 90B -3.69498
PRSS50 protease, serine, 50 -3.68502
WNT7A wingless-type MMTV integration site family, member 7A -3.68354
FOLR3 folate receptor 3 (gamma) -3.67713
CXCL5 chemokine (C-X-C motif) ligand 5 -3.67064
RFK riboflavin kinase -3.66918
CELF3 CUGBP, Elav-like family member 3 -3.63012
DIRAS2 DIRAS family, GTP-binding RAS-like 2 -3.62962
DTX3 deltex 3, E3 ubiquitin ligase -3.62786
STAU1 staufen double-stranded RNA binding protein 1 -3.62273
KRT8 keratin 8, type II -3.61675
BCL2 B-cell CLL/lymphoma 2 -3.61596
GRIA4 glutamate receptor, ionotropic, AMPA 4 -3.61081
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase -3.59882
SV2A synaptic vesicle glycoprotein 2A -3.59591
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -3.57104
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled -3.57015
RAVER2 ribonucleoprotein, PTB-binding 2 -3.56704
SLC35E1 solute carrier family 35, member E1 -3.56418
ALCAM activated leukocyte cell adhesion molecule -3.56268
CLEC4M C-type lectin domain family 4, member M -3.55606
GCG glucagon -3.55379
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -3.5525
METTL9 methyltransferase like 9 -3.55103
CNGB1 cyclic nucleotide gated channel beta 1 -3.5501
SLA Src-like-adaptor -3.54989
AKAP8L A kinase (PRKA) anchor protein 8-like -3.54653
TWF1 twinfilin actin binding protein 1 -3.54556
BMAL1 basic helix-loop-helix ARNT like 1 -3.54313
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -3.54292
NSG2 neuronal vesicle trafficking associated 2 -3.53573
MAPK1 mitogen-activated protein kinase 1 -3.53541
RAB11FIP2 RAB11 family interacting protein 2 (class I) -3.53116
GREM1 gremlin 1, DAN family BMP antagonist -3.53102
MPPED2 metallophosphoesterase domain containing 2 -3.531
RAG2 recombination activating gene 2 -3.5269
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase -3.52687
ZNF749 zinc finger protein 749 -3.52652
FBXO4 F-box protein 4 -3.5137
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -3.50941
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -3.50472
MYT1L myelin transcription factor 1-like -3.49912
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 -3.49681
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 -3.4918
LRP5L low density lipoprotein receptor-related protein 5-like -3.48816
PCDHB8 protocadherin beta 8 -3.48788
TESPA1 thymocyte expressed, positive selection associated 1 -3.48528
RHD Rh blood group, D antigen -3.47966
OR7A10 olfactory receptor, family 7, subfamily A, member 10 -3.47772
PODNL1 podocan-like 1 -3.47478
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -3.4707
ADAM9 ADAM metallopeptidase domain 9 -3.46707
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.46355
GAPVD1 GTPase activating protein and VPS9 domains 1 -3.46339
COLEC11 collectin sub-family member 11 -3.46023
ASB8 ankyrin repeat and SOCS box containing 8 -3.45932
GRAP GRB2-related adaptor protein -3.45764
RIT1 Ras-like without CAAX 1 -3.44717
WNT5A wingless-type MMTV integration site family, member 5A -3.44558
PPA1 pyrophosphatase (inorganic) 1 -3.44393
CD247 CD247 molecule -3.44024
SCNM1 sodium channel modifier 1 -3.43799
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -3.43764
KDM4A lysine (K)-specific demethylase 4A -3.42507
CCNA2 cyclin A2 -3.42301
JAKMIP2 janus kinase and microtubule interacting protein 2 -3.42147
SMNDC1 survival motor neuron domain containing 1 -3.41965
DOC2A double C2-like domains, alpha -3.41876
OSBP2 oxysterol binding protein 2 -3.41699
PTK2B protein tyrosine kinase 2 beta -3.4157
H2BC17 H2B clustered histone 17 -3.41027
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 -3.40057
PHF24 PHD finger protein 24 -3.39644
PRSS22 protease, serine, 22 -3.39173
KLF7 Kruppel-like factor 7 (ubiquitous) -3.39073
FOCAD focadhesin -3.388
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome -3.38768
AKAP7 A kinase (PRKA) anchor protein 7 -3.38092
SIRT3 sirtuin 3 -3.3804
ZNF205-AS1 ZNF205 antisense RNA 1 -3.37612
GPR173 G protein-coupled receptor 173 -3.37285
RNF121 ring finger protein 121 -3.37221
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 -3.3722
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 -3.37042
IL32 interleukin 32 -3.36988
BAG1 BCL2-associated athanogene -3.365
MGMT O-6-methylguanine-DNA methyltransferase -3.36358
RFPL1S RFPL1 antisense RNA 1 -3.36346
ATP5PB ATP synthase peripheral stalk-membrane subunit b -3.35998
BBOF1 basal body orientation factor 1 -3.35896
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 -3.35699
VENTX VENT homeobox -3.35498
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase -3.35215
GPR176 G protein-coupled receptor 176 -3.35135
RIMBP2 RIMS binding protein 2 -3.34655
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 -3.34319
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 -3.338
EFCC1 EF-hand and coiled-coil domain containing 1 -3.33675
ALLC allantoicase -3.33268
CPA1 carboxypeptidase A1 (pancreatic) -3.33106
GBAP1 glucosidase, beta, acid pseudogene 1 -3.32807
ZNF512B zinc finger protein 512B -3.32186
SHOX short stature homeobox -3.31792
DLX5 distal-less homeobox 5 -3.31673
EIF2D eukaryotic translation initiation factor 2D -3.31664
PHACTR1 phosphatase and actin regulator 1 -3.31643
GLA galactosidase, alpha -3.29242
TBX3 T-box 3 -3.28785
ANKRD12 ankyrin repeat domain 12 -3.2858
ADCY10 adenylate cyclase 10 (soluble) -3.27598
GOLT1B golgi transport 1B -3.27498
KMT5A lysine methyltransferase 5A -3.27129
ZNF83 zinc finger protein 83 -3.26994
MAPRE3 microtubule-associated protein, RP/EB family, member 3 -3.26948
PAQR5 progestin and adipoQ receptor family member V -3.26
RAD23B RAD23 homolog B (S. cerevisiae) -3.25875
STMN2 stathmin 2 -3.25598
TBXA2R thromboxane A2 receptor -3.25408
MMP17 matrix metallopeptidase 17 (membrane-inserted) -3.2506
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -3.24711
RUNDC3A RUN domain containing 3A -3.24253
H4C1 H4 clustered histone 1 -3.24077
FOXL1 forkhead box L1 -3.23518
DENND1B DENN/MADD domain containing 1B -3.23299
MTMR10 myotubularin related protein 10 -3.22084
MTMR2 myotubularin related protein 2 -3.22012
OCA2 oculocutaneous albinism II -3.21987
RNF2 ring finger protein 2 -3.21147
DOCK10 dedicator of cytokinesis 10 -3.21049
PNMA1 paraneoplastic Ma antigen 1 -3.20535
SPTBN4 spectrin, beta, non-erythrocytic 4 -3.20162
GPR6 G protein-coupled receptor 6 -3.20124
DCTN2 dynactin 2 (p50) -3.19702
GPR88 G protein-coupled receptor 88 -3.19401
ZNF550 zinc finger protein 550 -3.17904
MSL3 male-specific lethal 3 homolog (Drosophila) -3.17694
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) -3.17294
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial -3.1709
XPOT exportin, tRNA -3.16734
PFDN6 prefoldin subunit 6 -3.16641
CHIT1 chitinase 1 (chitotriosidase) -3.16307
PDPK1 3-phosphoinositide dependent protein kinase 1 -3.16219
PLSCR1 phospholipid scramblase 1 -3.1621
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -3.16049
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -3.15989
UNC45A unc-45 homolog A (C. elegans) -3.15732
CPNE1 copine I -3.15347
GRK3 G protein-coupled receptor kinase 3 -3.15013
ANTXR1 anthrax toxin receptor 1 -3.14956
C1ORF116 chromosome 1 open reading frame 116 -3.14717
ZNF8 zinc finger protein 8 -3.14224
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 -3.1418
SIGLEC8 sialic acid binding Ig-like lectin 8 -3.14097
TSPAN7 tetraspanin 7 -3.13946
SH2D3C SH2 domain containing 3C -3.13861
MYH13 myosin, heavy chain 13, skeletal muscle -3.13699
EPHA7 EPH receptor A7 -3.13496
PNLIPRP1 pancreatic lipase-related protein 1 -3.13488
STX18 syntaxin 18 -3.13448
CEP63 centrosomal protein 63kDa -3.13086
DMTN dematin actin binding protein -3.12915
OPRK1 opioid receptor, kappa 1 -3.12187
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) -3.1216
ST14 suppression of tumorigenicity 14 (colon carcinoma) -3.11871
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) -3.115
ARID3A AT rich interactive domain 3A (BRIGHT-like) -3.1138
OR3A1 olfactory receptor, family 3, subfamily A, member 1 -3.11235
SIT1 signaling threshold regulating transmembrane adaptor 1 -3.10633
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 -3.10536
KDM8 lysine (K)-specific demethylase 8 -3.10375
TUFM Tu translation elongation factor, mitochondrial -3.09903
H2BC11 H2B clustered histone 11 -3.09885
HEXB hexosaminidase B (beta polypeptide) -3.09742
ATXN3 ataxin 3 -3.08747
DNASE2B deoxyribonuclease II beta -3.08658
ITGA8 integrin, alpha 8 -3.08576
BMP7 bone morphogenetic protein 7 -3.08437
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -3.07705
DNASE1 deoxyribonuclease I -3.07629
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 -3.07527
LSG1 large 60S subunit nuclear export GTPase 1 -3.07396
AMIGO2 adhesion molecule with Ig-like domain 2 -3.07271
IFRD2 interferon-related developmental regulator 2 -3.06925
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -3.06741
OR2W1 olfactory receptor, family 2, subfamily W, member 1 -3.06606
MSH3 mutS homolog 3 -3.06436
TRAF3 TNF receptor-associated factor 3 -3.06275
SERGEF secretion regulating guanine nucleotide exchange factor -3.06061
GS1-600G8.3 unknown transcript -3.06021
TMEM161A transmembrane protein 161A -3.058
TACC1 transforming, acidic coiled-coil containing protein 1 -3.05264
RNF170 ring finger protein 170 -3.05112
ATP9A ATPase, class II, type 9A -3.05093
ENG endoglin -3.04716
JPH3 junctophilin 3 -3.04632
TREM1 triggering receptor expressed on myeloid cells 1 -3.04498
WFDC1 WAP four-disulfide core domain 1 -3.04468
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 -3.04061
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 -3.03749
UQCRC2 ubiquinol-cytochrome c reductase core protein II -3.03723
TARBP2 TAR (HIV-1) RNA binding protein 2 -3.03332
PHACTR4 phosphatase and actin regulator 4 -3.0328
VAV3 vav 3 guanine nucleotide exchange factor -3.03163
PAGE1 P antigen family, member 1 (prostate associated) -3.03131
HROB homologous recombination factor with OB-fold -3.03079
OXT oxytocin/neurophysin I prepropeptide -3.02805
BTN3A2 butyrophilin, subfamily 3, member A2 -3.02685
GALK1 galactokinase 1 -3.02567
LZTS1 leucine zipper, putative tumor suppressor 1 -3.02539
GPR135 G protein-coupled receptor 135 -3.02256
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -3.02109
B9D2 B9 protein domain 2 -3.01903
ADNP activity-dependent neuroprotector homeobox -3.0172
CREBZF CREB/ATF bZIP transcription factor -3.01633
MMD monocyte to macrophage differentiation-associated -3.01268
ALG8 ALG8, alpha-1,3-glucosyltransferase -3.01255
NAGLU N-acetylglucosaminidase, alpha -3.0121
RSRC1 arginine/serine-rich coiled-coil 1 -3.01152
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I -3.01072
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 -3.01061
NSD3 nuclear receptor binding SET domain protein 3 -3.01025
MFSD12 major facilitator superfamily domain containing 12 -3.00017