| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the debrisoquine-1591 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADD2 | adducin 2 (beta) |
| ALOXE3 | arachidonate lipoxygenase 3 |
| ALS2CL | ALS2 C-terminal like |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| BCAN | brevican |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BPI | bactericidal/permeability-increasing protein |
| C2CD2L | C2CD2-like |
| C4BPA | complement component 4 binding protein, alpha |
| CA7 | carbonic anhydrase VII |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAMK1G | calcium/calmodulin-dependent protein kinase IG |
| CANT1 | calcium activated nucleotidase 1 |
| CASD1 | CAS1 domain containing 1 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDK16 | cyclin-dependent kinase 16 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 |
| CKB | creatine kinase, brain |
| CRYM | crystallin, mu |
| CTRC | chymotrypsin C (caldecrin) |
| CYB561 | cytochrome b561 |
| DHFR | dihydrofolate reductase |
| DOK2 | docking protein 2, 56kDa |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| DRG2 | developmentally regulated GTP binding protein 2 |
| ECE1 | endothelin converting enzyme 1 |
| EDA | ectodysplasin A |
| EDAR | ectodysplasin A receptor |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| EMC1 | ER membrane protein complex subunit 1 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GRK6 | G protein-coupled receptor kinase 6 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSTM5 | glutathione S-transferase mu 5 |
| HFE | hemochromatosis |
| HIST1H2BE | histone cluster 1, H2be |
| HOXC11 | homeobox C11 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| KDM2A | lysine (K)-specific demethylase 2A |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| KRT6B | keratin 6B, type II |
| KRT8 | keratin 8, type II |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MISP | mitotic spindle positioning |
| MLYCD | malonyl-CoA decarboxylase |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MXD4 | MAX dimerization protein 4 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| PADI1 | peptidyl arginine deiminase, type I |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PAX1 | paired box 1 |
| PIAS4 | protein inhibitor of activated STAT, 4 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PSG6 | pregnancy specific beta-1-glycoprotein 6 |
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 |
| PVR | poliovirus receptor |
| RAB6B | RAB6B, member RAS oncogene family |
| RABEPK | Rab9 effector protein with kelch motifs |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RIOK3 | RIO kinase 3 |
| RORC | RAR-related orphan receptor C |
| RRBP1 | ribosome binding protein 1 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SEC31B | SEC31 homolog B (S. cerevisiae) |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SP140L | SP140 nuclear body protein-like |
| SPATS2 | spermatogenesis associated, serine-rich 2 |
| SPN | sialophorin |
| SPON2 | spondin 2, extracellular matrix protein |
| STK19 | serine/threonine kinase 19 |
| TBXA2R | thromboxane A2 receptor |
| TCF3 | transcription factor 3 |
| TMCO1 | transmembrane and coiled-coil domains 1 |
| TMEM63A | transmembrane protein 63A |
| TNS1 | tensin 1 |
| TPBG | trophoblast glycoprotein |
| TRIM45 | tripartite motif containing 45 |
| TSPAN32 | tetraspanin 32 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| YY2 | YY2 transcription factor |
| ZDHHC24 | zinc finger, DHHC-type containing 24 |
| Symbol | Name |
|---|---|
| ABCB7 | ATP-binding cassette, sub-family B (MDR/TAP), member 7 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase |
| ABT1 | activator of basal transcription 1 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| AHCTF1 | AT hook containing transcription factor 1 |
| ANKRD40 | ankyrin repeat domain 40 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ATXN2 | ataxin 2 |
| BCL10 | B-cell CLL/lymphoma 10 |
| BCL7B | B-cell CLL/lymphoma 7B |
| BCOR | BCL6 corepressor |
| BTK | Bruton agammaglobulinemia tyrosine kinase |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CD82 | CD82 molecule |
| CDK5 | cyclin-dependent kinase 5 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 |
| CDK9 | cyclin-dependent kinase 9 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CPOX | coproporphyrinogen oxidase |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
| DPP3 | dipeptidyl-peptidase 3 |
| DSN1 | DSN1, MIS12 kinetochore complex component |
| DYSF | dysferlin |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
| FHOD1 | formin homology 2 domain containing 1 |
| GPATCH2 | G patch domain containing 2 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HOOK2 | hook microtubule-tethering protein 2 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HYOU1 | hypoxia up-regulated 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA1551 | KIAA1551 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LIAS | lipoic acid synthetase |
| MED17 | mediator complex subunit 17 |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MNT | MAX network transcriptional repressor |
| MRPS15 | mitochondrial ribosomal protein S15 |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NHLRC2 | NHL repeat containing 2 |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) |
| ORC1 | origin recognition complex, subunit 1 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PCTP | phosphatidylcholine transfer protein |
| PGRMC2 | progesterone receptor membrane component 2 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PRMT3 | protein arginine methyltransferase 3 |
| PRPSAP2 | phosphoribosyl pyrophosphate synthetase-associated protein 2 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RAB4B | RAB4B, member RAS oncogene family |
| RCOR3 | REST corepressor 3 |
| RPAP3 | RNA polymerase II associated protein 3 |
| RRAGA | Ras-related GTP binding A |
| RUFY2 | RUN and FYVE domain containing 2 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SAR1B | secretion associated, Ras related GTPase 1B |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SECISBP2L | SECIS binding protein 2-like |
| SF3B4 | splicing factor 3b, subunit 4, 49kDa |
| SIRT6 | sirtuin 6 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SNX5 | sorting nexin 5 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAOK1 | TAO kinase 1 |
| THAP7 | THAP domain containing 7 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM135 | transmembrane protein 135 |
| TMEM243 | transmembrane protein 243, mitochondrial |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TTBK2 | tau tubulin kinase 2 |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| UBE3C | ubiquitin protein ligase E3C |
| USP8 | ubiquitin specific peptidase 8 |
| XAF1 | XIAP associated factor 1 |
| XDH | xanthine dehydrogenase |
| YEATS2 | YEATS domain containing 2 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 |
| ZNF106 | zinc finger protein 106 |
| ZNF273 | zinc finger protein 273 |
| ZNF652 | zinc finger protein 652 |
| ZXDC | ZXD family zinc finger C |
| ZZZ3 | zinc finger, ZZ-type containing 3 |
