decamethonium Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
Description A quaternary ammonium ion that is a depolarising muscle relaxant whose structure comprises a decane-1,10-diamine core in which each amino group carries three methyl substituents. (Chemical Entities of Biological Interest Ontology, CHEBI_41934)
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Genes

643 genes differentially expressed following the decamethonium small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CIAO3 cytosolic iron-sulfur assembly component 3 8.37828
VPREB3 pre-B lymphocyte 3 6.65477
TNC tenascin C 6.03582
SOX11 SRY (sex determining region Y)-box 11 5.99317
COLEC12 collectin sub-family member 12 5.60264
PLCL1 phospholipase C-like 1 5.52775
FXR1 fragile X mental retardation, autosomal homolog 1 5.3532
RAG1 recombination activating gene 1 5.29503
SIRT3 sirtuin 3 5.08629
MYH4 myosin, heavy chain 4, skeletal muscle 5.0787
RGSL1 regulator of G-protein signaling like 1 5.0455
PLAC1 placenta-specific 1 5.02432
GPC3 glypican 3 4.89972
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) 4.8666
PCCA propionyl CoA carboxylase, alpha polypeptide 4.82971
GPC4 glypican 4 4.81446
PDCD1LG2 programmed cell death 1 ligand 2 4.80726
HOXB9 homeobox B9 4.74769
RPS3 ribosomal protein S3 4.67166
FOXJ3 forkhead box J3 4.66403
NELFE negative elongation factor complex member E 4.64296
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 4.6429
CCNE2 cyclin E2 4.62774
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 4.61681
PLEKHO1 pleckstrin homology domain containing, family O member 1 4.57358
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 4.55603
EMC3 ER membrane protein complex subunit 3 4.55099
SELENOP selenoprotein P 4.54899
ASTN2 astrotactin 2 4.54408
IL17B interleukin 17B 4.51917
VSNL1 visinin-like 1 4.51507
METTL25B methyltransferase like 25B 4.49232
BMI1 BMI1 proto-oncogene, polycomb ring finger 4.48057
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 4.47981
MPPED2 metallophosphoesterase domain containing 2 4.47241
FST follistatin 4.44986
LPAR3 lysophosphatidic acid receptor 3 4.43086
SNAP25 synaptosomal-associated protein, 25kDa 4.37119
EMC7 ER membrane protein complex subunit 7 4.35088
ELP1 elongator acetyltransferase complex subunit 1 4.34111
SLC35A5 solute carrier family 35, member A5 4.33657
KCNK2 potassium channel, two pore domain subfamily K, member 2 4.28579
MRPS16 mitochondrial ribosomal protein S16 4.27563
COPZ2 coatomer protein complex, subunit zeta 2 4.26982
HABP4 hyaluronan binding protein 4 4.24691
ERGIC2 ERGIC and golgi 2 4.23399
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 4.23159
CSNK1G1 casein kinase 1, gamma 1 4.22899
PCOLCE procollagen C-endopeptidase enhancer 4.21482
MAGED2 melanoma antigen family D2 4.21321
HYAL4 hyaluronoglucosaminidase 4 4.1643
ACKR2 atypical chemokine receptor 2 4.1546
AUH AU RNA binding protein/enoyl-CoA hydratase 4.14233
NRIP3 nuclear receptor interacting protein 3 4.10439
RABGAP1 RAB GTPase activating protein 1 4.10174
CNTNAP2 contactin associated protein-like 2 4.09757
GBAP1 glucosidase, beta, acid pseudogene 1 4.08724
FCRL2 Fc receptor-like 2 4.06844
UBA7 ubiquitin-like modifier activating enzyme 7 4.06563
ARHGAP24 Rho GTPase activating protein 24 4.05843
ALX1 ALX homeobox 1 4.0581
STK3 serine/threonine kinase 3 4.04713
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 4.03111
RPS5 ribosomal protein S5 4.02919
WDR6 WD repeat domain 6 4.01648
SDC3 syndecan 3 4.00758
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 3.99362
WBP1L WW domain binding protein 1-like 3.98838
BDKRB1 bradykinin receptor B1 3.98561
PSG2 pregnancy specific beta-1-glycoprotein 2 3.96354
PLEKHA8P1 pleckstrin homology domain containing, family A member 8 pseudogene 1 3.95344
IRF1 interferon regulatory factor 1 3.94621
ARID5B AT rich interactive domain 5B (MRF1-like) 3.94433
NACA4P NACA family member 4, pseudogene 3.92723
NEFH neurofilament, heavy polypeptide 3.92579
TMSB10 thymosin beta 10 3.91899
SMCP sperm mitochondria-associated cysteine-rich protein 3.91638
RPS25 ribosomal protein S25 3.91403
KYAT1 kynurenine aminotransferase 1 3.89034
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 3.88901
NTS neurotensin 3.88565
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 3.87651
GPR17 G protein-coupled receptor 17 3.87517
AAR2 AAR2 splicing factor homolog (S. cerevisiae) 3.86045
CLCN7 chloride channel, voltage-sensitive 7 3.85724
SCRG1 stimulator of chondrogenesis 1 3.85666
RPL32 ribosomal protein L32 3.83776
SCN1A sodium channel, voltage gated, type I alpha subunit 3.82674
OSBPL9 oxysterol binding protein-like 9 3.80495
CHEK2 checkpoint kinase 2 3.78954
HOXC6 homeobox C6 3.78606
PTPRG protein tyrosine phosphatase, receptor type, G 3.78207
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 3.7791
FSD1 fibronectin type III and SPRY domain containing 1 3.77343
RXRG retinoid X receptor, gamma 3.77296
COL9A1 collagen, type IX, alpha 1 3.77045
OSBPL10 oxysterol binding protein-like 10 3.76958
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 3.76387
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 3.76365
ART1 ADP-ribosyltransferase 1 3.76356
SOX2 SRY (sex determining region Y)-box 2 3.76194
MICU1 mitochondrial calcium uptake 1 3.7605
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 3.75588
FSCN3 fascin actin-bundling protein 3, testicular 3.74942
GPX7 glutathione peroxidase 7 3.74668
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 3.74405
VSTM4 V-set and transmembrane domain containing 4 3.74183
KCTD7 potassium channel tetramerization domain containing 7 3.72846
AP2B1 adaptor-related protein complex 2, beta 1 subunit 3.72736
ATG10 autophagy related 10 3.72736
DPEP1 dipeptidase 1 (renal) 3.7226
ZNF423 zinc finger protein 423 3.71347
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 3.7101
CRAT carnitine O-acetyltransferase 3.70391
CCR4 chemokine (C-C motif) receptor 4 3.70089
LAMA4 laminin, alpha 4 3.7006
DRD2 dopamine receptor D2 3.69151
TUBB2B tubulin, beta 2B class IIb 3.6866
BCL2 B-cell CLL/lymphoma 2 3.6842
ACTL6A actin-like 6A 3.68037
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 3.67957
TCL1A T-cell leukemia/lymphoma 1A 3.67409
RAB30 RAB30, member RAS oncogene family 3.6713
ACVR2B-AS1 ACVR2B antisense RNA 1 3.66875
MYH15 myosin, heavy chain 15 3.6676
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 3.66471
GAP43 growth associated protein 43 3.66435
PEX2 peroxisomal biogenesis factor 2 3.65915
MAB21L2 mab-21-like 2 (C. elegans) 3.63942
PTDSS1 phosphatidylserine synthase 1 3.63433
STMN2 stathmin 2 3.62038
RNF13 ring finger protein 13 3.61917
CHEK1 checkpoint kinase 1 3.61377
EMILIN1 elastin microfibril interfacer 1 3.61259
GNPAT glyceronephosphate O-acyltransferase 3.6076
PLEKHJ1 pleckstrin homology domain containing, family J member 1 3.60081
INE1 inactivation escape 1 (non-protein coding) 3.59113
SEC62 SEC62 homolog (S. cerevisiae) 3.58989
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 3.58832
INTS13 integrator complex subunit 13 3.58188
HAX1 HCLS1 associated protein X-1 3.58113
BMP7 bone morphogenetic protein 7 3.57909
ITFG1 integrin alpha FG-GAP repeat containing 1 3.57537
STAT1 signal transducer and activator of transcription 1, 91kDa 3.56648
STC2 stanniocalcin 2 3.5663
HOXD9 homeobox D9 3.56199
TMBIM4 transmembrane BAX inhibitor motif containing 4 3.56113
OR1F1 olfactory receptor, family 1, subfamily F, member 1 3.55549
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 3.55385
PHOX2B paired-like homeobox 2b 3.55378
ARL4D ADP-ribosylation factor-like 4D 3.54799
SEPTIN10 septin 10 3.54789
TAGLN3 transgelin 3 3.54327
GOLM1 golgi membrane protein 1 3.53785
INHA inhibin, alpha 3.5301
TAS2R3 taste receptor, type 2, member 3 3.52799
HEXA hexosaminidase A (alpha polypeptide) 3.52743
CCR3 chemokine (C-C motif) receptor 3 3.51726
TCL1B T-cell leukemia/lymphoma 1B 3.51562
YPEL1 yippee-like 1 (Drosophila) 3.51192
PRDM5 PR domain containing 5 3.50838
TWIST1 twist family bHLH transcription factor 1 3.50812
NCKAP1 NCK-associated protein 1 3.50091
CETN1 centrin, EF-hand protein, 1 3.49806
RPS24 ribosomal protein S24 3.49478
MTERF3 mitochondrial transcription termination factor 3 3.49308
FAM110B family with sequence similarity 110, member B 3.49282
AMBN ameloblastin (enamel matrix protein) 3.47748
BLNK B-cell linker 3.46508
MRPS15 mitochondrial ribosomal protein S15 3.45305
KDM5B lysine (K)-specific demethylase 5B 3.44983
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 3.44957
MAP2 microtubule-associated protein 2 3.4456
EFNB1 ephrin-B1 3.44482
TTC23 tetratricopeptide repeat domain 23 3.44239
OPHN1 oligophrenin 1 3.43364
GRP gastrin-releasing peptide 3.43157
CUEDC2 CUE domain containing 2 3.42917
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 3.42347
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 3.41742
PITPNB phosphatidylinositol transfer protein, beta 3.41397
STMN4 stathmin-like 4 3.407
PRPH peripherin 3.40565
CYTH4 cytohesin 4 3.40407
NEFM neurofilament, medium polypeptide 3.39597
KRT38 keratin 38, type I 3.39421
MMP16 matrix metallopeptidase 16 (membrane-inserted) 3.39344
RASL11B RAS-like, family 11, member B 3.39197
CNPY3 canopy FGF signaling regulator 3 3.39004
WRNIP1 Werner helicase interacting protein 1 3.3893
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 3.38893
ENOPH1 enolase-phosphatase 1 3.38212
CCIN calicin 3.37712
PAIP1 poly(A) binding protein interacting protein 1 3.37014
RETREG3 reticulophagy regulator family member 3 3.36931
GNB5 guanine nucleotide binding protein (G protein), beta 5 3.36503
HDAC11 histone deacetylase 11 3.36472
DOLK dolichol kinase 3.36255
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 3.36168
GHRH growth hormone releasing hormone 3.35473
MPZ myelin protein zero 3.35465
IMPG2 interphotoreceptor matrix proteoglycan 2 3.35386
MAPK13 mitogen-activated protein kinase 13 3.35226
STMN3 stathmin-like 3 3.35132
SCD5 stearoyl-CoA desaturase 5 3.35016
VAMP3 vesicle-associated membrane protein 3 3.34795
LOC730101 uncharacterized LOC730101 3.32924
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 3.32893
TNMD tenomodulin 3.3272
C1ORF105 chromosome 1 open reading frame 105 3.32543
ELAVL4 ELAV like neuron-specific RNA binding protein 4 3.32454
C19ORF53 chromosome 19 open reading frame 53 3.32371
LEPROT leptin receptor overlapping transcript 3.32271
SERHL2 serine hydrolase-like 2 3.32167
YPEL5 yippee-like 5 (Drosophila) 3.31644
RPS2 ribosomal protein S2 3.31288
LEF1 lymphoid enhancer-binding factor 1 3.31025
SOX5 SRY (sex determining region Y)-box 5 3.30716
HEMK1 HemK methyltransferase family member 1 3.30553
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 3.29082
CCDC144A coiled-coil domain containing 144A 3.28809
FBXO38 F-box protein 38 3.28469
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa 3.28246
BRME1 break repair meiotic recombinase recruitment factor 1 3.28219
FANCE Fanconi anemia, complementation group E 3.28083
EIF5B eukaryotic translation initiation factor 5B 3.28066
RPL7A ribosomal protein L7a 3.27972
CDC14B cell division cycle 14B 3.27971
PDE7B phosphodiesterase 7B 3.27926
DLL3 delta-like 3 (Drosophila) 3.27917
MRNIP MRN complex interacting protein 3.27902
RPL30 ribosomal protein L30 3.27825
BEND5 BEN domain containing 5 3.27683
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 3.27532
RPLP1 ribosomal protein, large, P1 3.27315
STK19 serine/threonine kinase 19 3.27252
PSAT1 phosphoserine aminotransferase 1 3.26998
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 3.26991
FBN2 fibrillin 2 3.26928
TMEM80 transmembrane protein 80 3.26456
POMT1 protein-O-mannosyltransferase 1 3.26418
GNG7 guanine nucleotide binding protein (G protein), gamma 7 3.26191
TIAM1 T-cell lymphoma invasion and metastasis 1 3.26182
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 3.25909
NAP1L1 nucleosome assembly protein 1-like 1 3.25467
KIF26B kinesin family member 26B 3.25449
GFER growth factor, augmenter of liver regeneration 3.25183
IFI6 interferon, alpha-inducible protein 6 3.25165
VCAM1 vascular cell adhesion molecule 1 3.25139
RPL37 ribosomal protein L37 3.24919
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) 3.24535
IGFBP5 insulin-like growth factor binding protein 5 3.23553
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 3.23346
OR7C2 olfactory receptor, family 7, subfamily C, member 2 3.23319
NUP214 nucleoporin 214kDa 3.23273
RPL37A ribosomal protein L37a 3.23023
GP6 glycoprotein VI (platelet) 3.23007
ANGPT1 angiopoietin 1 3.22977
TBL2 transducin (beta)-like 2 3.225
PRM1 protamine 1 3.21909
RACK1 receptor for activated C kinase 1 3.21561
RAB13 RAB13, member RAS oncogene family 3.21011
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 3.20482
TPP2 tripeptidyl peptidase II 3.19929
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene) 3.19735
AQP2 aquaporin 2 (collecting duct) 3.1971
DPEP3 dipeptidase 3 3.19537
GTPBP3 GTP binding protein 3 (mitochondrial) 3.19155
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 3.18965
ITCH itchy E3 ubiquitin protein ligase 3.18297
FAM149B1 family with sequence similarity 149, member B1 3.18214
PHKG2 phosphorylase kinase, gamma 2 (testis) 3.17725
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 3.17724
ZPBP zona pellucida binding protein 3.17507
PDK1 pyruvate dehydrogenase kinase, isozyme 1 3.17433
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 3.17327
TREM2 triggering receptor expressed on myeloid cells 2 3.1715
CNR2 cannabinoid receptor 2 (macrophage) 3.16736
PEX19 peroxisomal biogenesis factor 19 3.16656
JPT2 Jupiter microtubule associated homolog 2 3.16009
STK32B serine/threonine kinase 32B 3.15989
WDR48 WD repeat domain 48 3.15892
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 3.15813
SH2D3C SH2 domain containing 3C 3.15807
EPPIN epididymal peptidase inhibitor 3.1545
PTN pleiotrophin 3.15294
HAPLN1 hyaluronan and proteoglycan link protein 1 3.15226
SCIN scinderin 3.14751
RETREG2 reticulophagy regulator family member 2 3.14682
VAX2 ventral anterior homeobox 2 3.14612
GADD45G growth arrest and DNA-damage-inducible, gamma 3.14345
RIC8A RIC8 guanine nucleotide exchange factor A 3.14311
UNC5C unc-5 homolog C (C. elegans) 3.14154
LPAR1 lysophosphatidic acid receptor 1 3.13978
STOM stomatin 3.13803
IGLL1 immunoglobulin lambda-like polypeptide 1 3.13731
PSG9 pregnancy specific beta-1-glycoprotein 9 3.13061
BMP6 bone morphogenetic protein 6 3.12864
SCMH1 sex comb on midleg homolog 1 (Drosophila) 3.12502
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 3.12309
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 3.11567
TMEM35A transmembrane protein 35A 3.11529
UXS1 UDP-glucuronate decarboxylase 1 3.11416
FKBP14 FK506 binding protein 14, 22 kDa 3.11117
TCF12 transcription factor 12 3.11041
ZNF148 zinc finger protein 148 3.10769
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 3.1028
IZUMO4 IZUMO family member 4 3.10166
GJB4 gap junction protein, beta 4, 30.3kDa 3.10142
DSPP dentin sialophosphoprotein 3.10109
COPS6 COP9 signalosome subunit 6 3.09806
IFNB1 interferon, beta 1, fibroblast 3.09662
PARK7 parkinson protein 7 3.09345
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 3.08807
PRCP prolylcarboxypeptidase (angiotensinase C) 3.08047
PSEN2 presenilin 2 3.07596
PEX11B peroxisomal biogenesis factor 11 beta 3.07203
ALK anaplastic lymphoma receptor tyrosine kinase 3.0688
KIF1A kinesin family member 1A 3.0682
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 3.06812
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 3.06769
SLCO3A1 solute carrier organic anion transporter family, member 3A1 3.06592
NUP155 nucleoporin 155kDa 3.05949
BTN1A1 butyrophilin, subfamily 1, member A1 3.05589
SUMO1 small ubiquitin-like modifier 1 3.0553
FBXO24 F-box protein 24 3.05068
GGPS1 geranylgeranyl diphosphate synthase 1 3.04733
EPHB2 EPH receptor B2 3.04728
RERE arginine-glutamic acid dipeptide (RE) repeats 3.04281
LRRC17 leucine rich repeat containing 17 3.04227
SIL1 SIL1 nucleotide exchange factor 3.04152
WDR45 WD repeat domain 45 3.03431
FCHSD2 FCH and double SH3 domains 2 3.0318
CNTRL centriolin 3.02785
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 3.02404
BACE2 beta-site APP-cleaving enzyme 2 3.02191
PRRX2 paired related homeobox 2 3.01862
ZNF215 zinc finger protein 215 3.0182
ORAI3 ORAI calcium release-activated calcium modulator 3 3.01543
EIF3H eukaryotic translation initiation factor 3, subunit H 3.01435
SDK2 sidekick cell adhesion molecule 2 3.01368
NAP1L4 nucleosome assembly protein 1-like 4 3.00132

decreased expression

Symbol Name Standardized Value
NOS3 nitric oxide synthase 3 (endothelial cell) -7.4195
ZCCHC2 zinc finger, CCHC domain containing 2 -6.88821
SIK1 salt-inducible kinase 1 -6.77538
GRAMD4 GRAM domain containing 4 -6.72593
RITA1 RBPJ interacting and tubulin associated 1 -6.46598
PFKL phosphofructokinase, liver -6.19324
PRKCH protein kinase C, eta -6.05643
DENND2D DENN/MADD domain containing 2D -5.64072
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -5.48702
POLR1C polymerase (RNA) I polypeptide C, 30kDa -5.4425
OCA2 oculocutaneous albinism II -5.38489
ADNP2 ADNP homeobox 2 -5.3214
H2BC13 H2B clustered histone 13 -5.30114
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 -5.21377
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -5.05115
ADRA1D adrenoceptor alpha 1D -4.99893
GCN1 GCN1 activator of EIF2AK4 -4.98328
SSH1 slingshot protein phosphatase 1 -4.96127
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -4.94896
DAP death-associated protein -4.83529
TOB1 transducer of ERBB2, 1 -4.76774
NPAS2 neuronal PAS domain protein 2 -4.76262
MRPL4 mitochondrial ribosomal protein L4 -4.70335
WDR7 WD repeat domain 7 -4.6909
TASP1 taspase, threonine aspartase, 1 -4.65841
ZBTB33 zinc finger and BTB domain containing 33 -4.65467
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae) -4.64237
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -4.6248
STAP2 signal transducing adaptor family member 2 -4.60369
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 -4.59172
TRAPPC10 trafficking protein particle complex 10 -4.52939
PDK3 pyruvate dehydrogenase kinase, isozyme 3 -4.5184
ACTN1 actinin, alpha 1 -4.49499
TBR1 T-box, brain, 1 -4.42355
PRELP proline/arginine-rich end leucine-rich repeat protein -4.42284
UPK2 uroplakin 2 -4.41243
MYH2 myosin, heavy chain 2, skeletal muscle, adult -4.37823
RUNX3 runt-related transcription factor 3 -4.37307
MAP7 microtubule-associated protein 7 -4.35491
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 -4.32805
KCTD14 potassium channel tetramerization domain containing 14 -4.32506
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 -4.32071
PFN1 profilin 1 -4.29888
PIGB phosphatidylinositol glycan anchor biosynthesis, class B -4.27779
FCHO1 FCH domain only 1 -4.27674
TTC21B tetratricopeptide repeat domain 21B -4.27136
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -4.25774
RAB17 RAB17, member RAS oncogene family -4.23727
CRISP3 cysteine-rich secretory protein 3 -4.21156
MUC5B mucin 5B, oligomeric mucus/gel-forming -4.18389
TYMS thymidylate synthetase -4.17978
PLCH1 phospholipase C, eta 1 -4.14465
TRMT9B tRNA methyltransferase 9B (putative) -4.14004
NISCH nischarin -4.13747
PHF10 PHD finger protein 10 -4.10822
TMPRSS4 transmembrane protease, serine 4 -4.08833
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 -4.06653
FAM124B family with sequence similarity 124B -4.06592
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -4.0554
SOX18 SRY (sex determining region Y)-box 18 -4.04376
PRKX protein kinase, X-linked -4.03299
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 -4.02008
CHKA choline kinase alpha -3.98748
NUAK1 NUAK family, SNF1-like kinase, 1 -3.98591
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) -3.97291
PPP1R16B protein phosphatase 1, regulatory subunit 16B -3.97169
KMT5A lysine methyltransferase 5A -3.9423
CD70 CD70 molecule -3.92972
MYL2 myosin, light chain 2, regulatory, cardiac, slow -3.92885
TPCN1 two pore segment channel 1 -3.92221
CAST calpastatin -3.91138
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 -3.91107
CPB1 carboxypeptidase B1 (tissue) -3.90367
ADAM8 ADAM metallopeptidase domain 8 -3.88847
DCC DCC netrin 1 receptor -3.88473
TCIM transcriptional and immune response regulator -3.88471
NR2E1 nuclear receptor subfamily 2, group E, member 1 -3.87884
MYOT myotilin -3.87523
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 -3.86925
CAMKMT calmodulin-lysine N-methyltransferase -3.86345
SNRPF small nuclear ribonucleoprotein polypeptide F -3.86236
PIEZO1 piezo-type mechanosensitive ion channel component 1 -3.86146
PCNT pericentrin -3.85528
GPR135 G protein-coupled receptor 135 -3.85261
CSN3 casein kappa -3.84028
CDH9 cadherin 9, type 2 (T1-cadherin) -3.82713
KHSRP KH-type splicing regulatory protein -3.81858
FXYD1 FXYD domain containing ion transport regulator 1 -3.79761
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -3.79316
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 -3.79116
SLC43A3 solute carrier family 43, member 3 -3.78599
CD300C CD300c molecule -3.77827
TRIAP1 TP53 regulated inhibitor of apoptosis 1 -3.77687
GSTM5 glutathione S-transferase mu 5 -3.7741
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -3.76946
KISS1 KiSS-1 metastasis-suppressor -3.76588
LGALS2 lectin, galactoside-binding, soluble, 2 -3.76581
IQCA1 IQ motif containing with AAA domain 1 -3.76435
OSBPL3 oxysterol binding protein-like 3 -3.74337
COG4 component of oligomeric golgi complex 4 -3.74251
IL18 interleukin 18 -3.73464
TLK2 tousled-like kinase 2 -3.72973
PCNA proliferating cell nuclear antigen -3.71375
CNR1 cannabinoid receptor 1 (brain) -3.71211
GALC galactosylceramidase -3.7118
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 -3.70479
PELO pelota homolog (Drosophila) -3.69727
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha -3.69492
ITM2A integral membrane protein 2A -3.69421
FHOD1 formin homology 2 domain containing 1 -3.69251
AHI1 Abelson helper integration site 1 -3.68363
N4BP2L1 NEDD4 binding protein 2-like 1 -3.68184
VAV1 vav 1 guanine nucleotide exchange factor -3.68176
HELZ helicase with zinc finger -3.68077
PRSS1 protease, serine, 1 (trypsin 1) -3.67788
MAVS mitochondrial antiviral signaling protein -3.67466
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa -3.66548
KLKB1 kallikrein B, plasma (Fletcher factor) 1 -3.6541
CSNK2A1 casein kinase 2, alpha 1 polypeptide -3.63143
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -3.62875
PODXL podocalyxin-like -3.62052
TPI1 triosephosphate isomerase 1 -3.62049
FANCA Fanconi anemia, complementation group A -3.61546
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -3.60833
TSPAN14 tetraspanin 14 -3.60665
MECP2 methyl CpG binding protein 2 -3.59602
TRAPPC14 trafficking protein particle complex subunit 14 -3.59546
CHN2 chimerin 2 -3.59208
CENPB centromere protein B, 80kDa -3.58611
ABHD6 abhydrolase domain containing 6 -3.58584
MAP7D3 MAP7 domain containing 3 -3.58549
SH2B3 SH2B adaptor protein 3 -3.58379
BHLHE40 basic helix-loop-helix family, member e40 -3.55615
POU3F1 POU class 3 homeobox 1 -3.55564
HDAC6 histone deacetylase 6 -3.55217
GPRC5C G protein-coupled receptor, class C, group 5, member C -3.53949
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -3.53554
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -3.53519
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) -3.53196
TESK1 testis-specific kinase 1 -3.52862
RHOF ras homolog family member F (in filopodia) -3.52226
RASL10A RAS-like, family 10, member A -3.50909
CA8 carbonic anhydrase VIII -3.50794
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 -3.50619
LY6H lymphocyte antigen 6 complex, locus H -3.50151
KRT19 keratin 19, type I -3.49764
BTBD1 BTB (POZ) domain containing 1 -3.49482
CARD9 caspase recruitment domain family, member 9 -3.49432
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -3.49153
USB1 U6 snRNA biogenesis 1 -3.49002
MCTP1 multiple C2 domains, transmembrane 1 -3.48363
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 -3.48243
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit -3.47598
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.46462
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 -3.4594
NOP56 NOP56 ribonucleoprotein -3.45926
ZNF185 zinc finger protein 185 (LIM domain) -3.45895
RIPK4 receptor-interacting serine-threonine kinase 4 -3.45337
CELF3 CUGBP, Elav-like family member 3 -3.45094
CRYBA2 crystallin, beta A2 -3.44326
OGFRL1 opioid growth factor receptor-like 1 -3.4412
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -3.43336
SAE1 SUMO1 activating enzyme subunit 1 -3.43016
DAZL deleted in azoospermia-like -3.42649
DAAM2 dishevelled associated activator of morphogenesis 2 -3.42007
SALL2 spalt-like transcription factor 2 -3.41427
BID BH3 interacting domain death agonist -3.41341
SART3 squamous cell carcinoma antigen recognized by T cells 3 -3.41141
PTPRB protein tyrosine phosphatase, receptor type, B -3.40505
FAS Fas cell surface death receptor -3.4047
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -3.40333
RCL1 RNA terminal phosphate cyclase-like 1 -3.39471
PARVB parvin, beta -3.39337
RCOR3 REST corepressor 3 -3.39307
SIRPA signal-regulatory protein alpha -3.38708
DOP1A DOP1 leucine zipper like protein A -3.38668
MYRF myelin regulatory factor -3.38516
PITPNA phosphatidylinositol transfer protein, alpha -3.37869
SUMO3 small ubiquitin-like modifier 3 -3.37264
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 -3.359
ADGRE1 adhesion G protein-coupled receptor E1 -3.35716
ZDHHC13 zinc finger, DHHC-type containing 13 -3.34779
BMP15 bone morphogenetic protein 15 -3.34262
FOXA2 forkhead box A2 -3.34262
ELF5 E74-like factor 5 (ets domain transcription factor) -3.34217
POLG polymerase (DNA directed), gamma -3.33584
TEX2 testis expressed 2 -3.33137
RASIP1 Ras interacting protein 1 -3.32997
ST20 suppressor of tumorigenicity 20 -3.32797
NEUROD1 neuronal differentiation 1 -3.32243
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase -3.32162
CYCS cytochrome c, somatic -3.3181
DENND1A DENN/MADD domain containing 1A -3.3127
TRPV5 transient receptor potential cation channel, subfamily V, member 5 -3.30885
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 -3.30475
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -3.29805
CHPT1 choline phosphotransferase 1 -3.29452
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -3.29072
HSPA8 heat shock 70kDa protein 8 -3.28763
FBXO21 F-box protein 21 -3.28688
DUSP2 dual specificity phosphatase 2 -3.27991
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta -3.27357
SLCO1C1 solute carrier organic anion transporter family, member 1C1 -3.26691
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -3.26622
RBM19 RNA binding motif protein 19 -3.26412
FOS FBJ murine osteosarcoma viral oncogene homolog -3.25928
G6PC2 glucose-6-phosphatase, catalytic, 2 -3.25394
PRODH proline dehydrogenase (oxidase) 1 -3.25043
BMAL1 basic helix-loop-helix ARNT like 1 -3.25036
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -3.24855
PVT1 Pvt1 oncogene (non-protein coding) -3.23464
SHROOM2 shroom family member 2 -3.22586
NPC1L1 NPC1-like 1 -3.21613
MREG melanoregulin -3.21603
PUS1 pseudouridylate synthase 1 -3.21543
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 -3.21439
CHI3L2 chitinase 3-like 2 -3.2129
LZTS3 leucine zipper, putative tumor suppressor family member 3 -3.21148
BATF basic leucine zipper transcription factor, ATF-like -3.20709
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 -3.20673
EVI5 ecotropic viral integration site 5 -3.20101
PAX6 paired box 6 -3.19999
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -3.19856
OPTN optineurin -3.19733
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -3.19261
ATP2A3 ATPase, Ca++ transporting, ubiquitous -3.19216
EHD4 EH-domain containing 4 -3.19081
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -3.19053
ANXA13 annexin A13 -3.18788
LYST lysosomal trafficking regulator -3.18089
PIH1D1 PIH1 domain containing 1 -3.16647
ANKMY1 ankyrin repeat and MYND domain containing 1 -3.16512
GARRE1 granule associated Rac and RHOG effector 1 -3.16494
HIGD1B HIG1 hypoxia inducible domain family, member 1B -3.15444
SPINT3 serine peptidase inhibitor, Kunitz type, 3 -3.15437
THAP11 THAP domain containing 11 -3.1529
MOCS1 molybdenum cofactor synthesis 1 -3.14514
GPHN gephyrin -3.14415
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -3.14188
NR2F1 nuclear receptor subfamily 2, group F, member 1 -3.13904
MYH7 myosin, heavy chain 7, cardiac muscle, beta -3.13847
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -3.13752
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -3.12678
S100A14 S100 calcium binding protein A14 -3.12313
WASHC4 WASH complex subunit 4 -3.12081
GNA12 guanine nucleotide binding protein (G protein) alpha 12 -3.11932
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -3.11923
FGFR3 fibroblast growth factor receptor 3 -3.11656
CLTB clathrin, light chain B -3.11511
GGCT gamma-glutamylcyclotransferase -3.11491
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) -3.11367
DPYD dihydropyrimidine dehydrogenase -3.11236
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 -3.10881
ZHX3 zinc fingers and homeoboxes 3 -3.10708
FBXO41 F-box protein 41 -3.10433
PCNX4 pecanex 4 -3.10431
SAFB scaffold attachment factor B -3.10241
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -3.10181
MLXIPL MLX interacting protein-like -3.10024
HCCS holocytochrome c synthase -3.09845
TMX1 thioredoxin-related transmembrane protein 1 -3.0966
CA3 carbonic anhydrase III -3.0872
RANBP10 RAN binding protein 10 -3.08587
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 -3.08452
CTNND1 catenin (cadherin-associated protein), delta 1 -3.08033
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -3.07963
ADORA1 adenosine A1 receptor -3.07941
INS insulin -3.079
EPHB6 EPH receptor B6 -3.07718
SEC23B Sec23 homolog B (S. cerevisiae) -3.06973
SEC24A SEC24 family member A -3.0686
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) -3.0662
ALOX5AP arachidonate 5-lipoxygenase-activating protein -3.06316
DDO D-aspartate oxidase -3.05982
MGST2 microsomal glutathione S-transferase 2 -3.0595
OR7C1 olfactory receptor, family 7, subfamily C, member 1 -3.05931
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -3.05789
MCTP2 multiple C2 domains, transmembrane 2 -3.05708
MYH1 myosin, heavy chain 1, skeletal muscle, adult -3.05665
FASN fatty acid synthase -3.05528
VANGL1 VANGL planar cell polarity protein 1 -3.05447
GDAP1 ganglioside induced differentiation associated protein 1 -3.052
RANBP3 RAN binding protein 3 -3.04744
TMEM74B transmembrane protein 74B -3.04669
RIC8B RIC8 guanine nucleotide exchange factor B -3.04515
LPA lipoprotein, Lp(a) -3.04458
IFNG interferon, gamma -3.04399
TBC1D2B TBC1 domain family, member 2B -3.04369
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -3.04343
RTL8A retrotransposon Gag like 8A -3.03853
KCNK5 potassium channel, two pore domain subfamily K, member 5 -3.03564
TNIP1 TNFAIP3 interacting protein 1 -3.03307
TNNC2 troponin C type 2 (fast) -3.03
PKP1 plakophilin 1 -3.02731
PHACTR2 phosphatase and actin regulator 2 -3.02381
ELF1 E74-like factor 1 (ets domain transcription factor) -3.01716
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) -3.01447
LARP4 La ribonucleoprotein domain family, member 4 -3.00959
CA5A carbonic anhydrase VA, mitochondrial -3.00488
ALX3 ALX homeobox 3 -3.00274
DAPK1 death-associated protein kinase 1 -3.00072