decreased cd4-positive, cd25-positive, alpha-beta regulatory t cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description a reduction in the number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release (Mammalian Phenotype Ontology, MP_0010169)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010169
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Genes

3 gene mutations causing the decreased cd4-positive, cd25-positive, alpha-beta regulatory t cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BATF basic leucine zipper transcription factor, ATF-like
FOXP3 forkhead box P3
IL2 interleukin 2