decreased circulating alanine transaminase level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description decreased concentration in the blood of the enzyme which transfers amino groups from l-alanine to 2 ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction (Mammalian Phenotype Ontology, MP_0002942)
External Link
Similar Terms
Downloads & Tools


27 gene mutations causing the decreased circulating alanine transaminase level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ASL argininosuccinate lyase
C3 complement component 3
CHD7 chromodomain helicase DNA binding protein 7
DBN1 drebrin 1
DLG4 discs, large homolog 4 (Drosophila)
FASLG Fas ligand (TNF superfamily, member 6)
FCMR Fc fragment of IgM receptor
FOXN1 forkhead box N1
G0S2 G0/G1 switch 2
LDHA lactate dehydrogenase A
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LTBP1 latent transforming growth factor beta binding protein 1
MYD88 myeloid differentiation primary response 88
NOS2 nitric oxide synthase 2, inducible
NR2C2 nuclear receptor subfamily 2, group C, member 2
PDE10A phosphodiesterase 10A
PEX3 peroxisomal biogenesis factor 3
PRF1 perforin 1 (pore forming protein)
SIK3 SIK family kinase 3
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
TBC1D10A TBC1 domain family, member 10A
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TRIM27 tripartite motif containing 27