decreased circulating aspartate transaminase level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less than normal concentration in the blood of this enzyme, which catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid; aids in diagnosis of viral hepatitis and myocardial infarction (Mammalian Phenotype Ontology, MP_0005632)
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17 gene mutations causing the decreased circulating aspartate transaminase level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGO1 argonaute RISC catalytic component 1
ASL argininosuccinate lyase
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CHD7 chromodomain helicase DNA binding protein 7
DBN1 drebrin 1
DLG4 discs, large homolog 4 (Drosophila)
G0S2 G0/G1 switch 2
LDHA lactate dehydrogenase A
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MYD88 myeloid differentiation primary response 88
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NOS2 nitric oxide synthase 2, inducible
NR2C2 nuclear receptor subfamily 2, group C, member 2
PEX3 peroxisomal biogenesis factor 3
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
TRIM27 tripartite motif containing 27
WWOX WW domain containing oxidoreductase