decreased circulating glucagon level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the blood concentration of the peptide hormone secreted by the alpha cells of the pancreas that normally plays an important role in regulation of blood glucose concentration, ketone metabolism, and several other biochemical and physiological processes (Mammalian Phenotype Ontology, MP_0002696)
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17 gene mutations causing the decreased circulating glucagon level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CHRM3 cholinergic receptor, muscarinic 3
CREBBP CREB binding protein
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
FFAR1 free fatty acid receptor 1
FOXA1 forkhead box A1
GHR growth hormone receptor
GNAS GNAS complex locus
GPER1 G protein-coupled estrogen receptor 1
GPR68 G protein-coupled receptor 68
NCOA3 nuclear receptor coactivator 3
ONECUT1 one cut homeobox 1
PCSK1 proprotein convertase subtilisin/kexin type 1
PDYN prodynorphin
PITPNA phosphatidylinositol transfer protein, alpha
SCG5 secretogranin V